A5072912292- Sepsis Diagnosis and Treatment
- Acute Kidney Injury Research
- Hyperglycemia and glycemic control in critically ill and hospitalized patients
- Diabetes Management and Research
- Trauma, Hemostasis, Coagulopathy, Resuscitation
- Hemodynamic Monitoring and Therapy
- COVID-19 Clinical Research Studies
- Cardiac, Anesthesia and Surgical Outcomes
- Intensive Care Unit Cognitive Disorders
- Cardiac Arrest and Resuscitation
- Long-Term Effects of COVID-19
- Chronic Kidney Disease and Diabetes
- Sulfur Compounds in Biology
- Traumatic Brain Injury and Neurovascular Disturbances
- Renal function and acid-base balance
- Diabetes and associated disorders
- Dialysis and Renal Disease Management
- Respiratory Support and Mechanisms
- Metabolism, Diabetes, and Cancer
- COVID-19 and healthcare impacts
- Trauma and Emergency Care Studies
- Electrolyte and hormonal disorders
- Folate and B Vitamins Research
- Metabolism and Genetic Disorders
- Liver Disease Diagnosis and Treatment
Karolinska Institutet
2016-2025
Karolinska University Hospital
2016-2025
Åbo Akademi University
2024
Oslo University Hospital
2024
University of Brighton
2022-2023
Uppsala University
1985-2022
Austin Hospital
2014-2020
Austin Health
2017-2020
Heidelberg Repatriation Hospital
2017
St Vincent’s Private Hospital Sydney
2017
MAIT cell activation and decline in blood are associated with COVID-19 severity, features that dynamically recover convalescence.
Dendritic cells (DCs) and monocytes are crucial mediators of innate adaptive immune responses during viral infection, but misdirected by these may contribute to immunopathology. Here, we performed high-dimensional flow cytometry-analysis focusing on mononuclear phagocyte (MNP) lineages in SARS-CoV-2-infected patients with moderate severe COVID-19. We provide a deep comprehensive map the MNP landscape A redistribution monocyte subsets toward intermediate general decrease circulating DCs was...
Hypercoagulability and thromboembolism are prominent features of severe COVID-19, ongoing anticoagulant use might be protective.We conducted a nationwide register-based cohort study in Sweden, February through May, 2020, to assess whether direct oral (DOAC) was associated with reduced risk hospital admission for laboratory-confirmed or composite intensive care unit (ICU) death due COVID-19.DOAC (n = 103 703) not COVID-19 (adjusted hazard ratio [aHR] [95% confidence interval] 1.00 [0.75-1.33]...
The trauma patient sustains numerous potentially harmful insults that may contribute to a notable risk of acute kidney injury (AKI). aim this study was investigate the incidence and identify factors for AKI in severely injured patients admitted intensive care unit (ICU). were followed up 1 year with respect survival end-stage renal disease.Trauma ICU more than 24 hours at Level I center included. outcome measure diagnosed Days 2 7 treatment. Regression analysis performed associated...
Acute Kidney Injury (AKI) is common in critical ill populations and its association with high short-term mortality well established. However, long-term risks of death renal dysfunction are poorly understood few studies exclude patients pre-existing disease, meaning outcome for de novo AKI has been difficult to elicit. We aimed compare the risk Chronic Disease (CKD), End Stage Renal (ESRD) critically without severe AKI.This cohort study was conducted between 2005 2011 Swedish intensive care...
Background: Cardiac patients may experience problems with sexual activity as a result of their disease, medications or anxiety and nurses play an important role in counselling. We studied the practice, responsibility confidence cardiac counselling these patients.
The study was designed to evaluate nitrogen needs in severely injured patients during the first week after trauma. Thirty-nine aged from 18 65 years with a burn or fractures of more than two long bones were studied. Energy requirements given parenterally as fat and glucose isocaloric amounts. randomized into five groups receiving different amounts zero 0.3 g kg body-weight-1 24 h-1. Daily cumulative balance, urinary 3-methylhistidine excretion retention calculated on days 2-8 With no...
We describe simple and precise methods for the determination of inorganic sulfate, ester total sulfur in urine. The are based on turbidimetry sulfate as barium presence a small amount preformed with polyethylene glycol stabilizing agent. Inorganic is directly determined, whereas measured after removal followed by acid hydrolysis. Total determined wet oxidation sample nitric perchloric vanadate catalyst. also report excretion values healthy persons self-selected diet. Men excrete...
We describe a method for rapid and specific measurement of thiocyanate in serum or urine. separate from interfering compounds by adsorbing it on an anion-exchange resin that has special affinity thiocyanate, then eluting with sodium perchlorate. The eluted is quantified modified König reaction, hypochlorite being used as the chlorinating reagent. Analytical recovery added to urine was quantitative; coefficient variation 2.3% both within-day between-day precision. Cyanide certain antibiotics...