A5062688559- Advanced Sensor and Energy Harvesting Materials
- Textile materials and evaluations
- Natural Fiber Reinforced Composites
- Immune Cell Function and Interaction
- Retinal Diseases and Treatments
- Retinal and Macular Surgery
- Interactive and Immersive Displays
- Liver Diseases and Immunity
- biodegradable polymer synthesis and properties
- Non-Invasive Vital Sign Monitoring
- Glaucoma and retinal disorders
- Bone Tissue Engineering Materials
- COVID-19 Clinical Research Studies
- Additive Manufacturing and 3D Printing Technologies
- EEG and Brain-Computer Interfaces
- Muscle activation and electromyography studies
- Architecture and Computational Design
- Retinal and Optic Conditions
- Long-Term Effects of COVID-19
- SARS-CoV-2 and COVID-19 Research
- Tactile and Sensory Interactions
- Cholangiocarcinoma and Gallbladder Cancer Studies
- IL-33, ST2, and ILC Pathways
- Blind Source Separation Techniques
- ECG Monitoring and Analysis
Karolinska University Hospital
2013-2024
Karolinska Institutet
2007-2024
University of Borås
2009-2024
University of Gothenburg
2019
Chalmers University of Technology
2007-2014
Integrated Cardio Metabolic Centre
2013
S:t Eriks Ögonsjukhus
2006-2007
Emory Eye Center
2006
Emory Healthcare
2006
Karolinska Development (Sweden)
2006
MAIT cell activation and decline in blood are associated with COVID-19 severity, features that dynamically recover convalescence.
Dendritic cells (DCs) and monocytes are crucial mediators of innate adaptive immune responses during viral infection, but misdirected by these may contribute to immunopathology. Here, we performed high-dimensional flow cytometry-analysis focusing on mononuclear phagocyte (MNP) lineages in SARS-CoV-2-infected patients with moderate severe COVID-19. We provide a deep comprehensive map the MNP landscape A redistribution monocyte subsets toward intermediate general decrease circulating DCs was...
The human fetal immune system is naturally exposed to maternal allogeneic cells, antibodies, and pathogens. As such, it faced with a considerable challenge respect the balance between reactivity tolerance. Here, we show that natural killer (NK) cells differentiate early in utero are highly responsive cytokines antibody-mediated stimulation but respond poorly HLA class I–negative target cells. Strikingly, expression of killer-cell immunoglobulin-like receptors (KIRs) did not educate NK...
Abstract Fiber-based scaffolds produced by textile manufacturing technology offer versatile materials for tissue engineering applications since a wide range of crucial scaffold parameters, including porosity, pore size and interconnectivity, can be accurately controlled using 3D weaving. In this study, we developed weavable, bioactive biodegradable composite fiber from poly (lactic acid) (PLA) hydroxyapatite powder melt spinning. Subsequently, these fibers were fabricated The differentiation...
Human innate lymphoid cells have been described to exist in different organs, with functional deregulation of these contributing several disease states. Here, we performed the first detailed characterization phenotype, tissue‐residency properties, and functionality ILC1s, ILC2s, ILC3s human adult fetal liver. In addition, investigated changes ILC compartment liver fibrosis. A unique composition tissue‐resident ILCs was observed nonfibrotic livers as compared that mucosal tissues, NKp44 −...
Bile ducts from patients with PSC are enriched in neutrophils and biliary-resident CD8 + T cells differ composition liver tissue.
The long-term monitoring of biophysiological signals requires new types sensor systems that are wearable and at the same time convenient for users. This paper describes design a novel garment-based sensing system breathing rhythm. concept was realized in prototype garment, integrated with coated piezoresistive sensors. garment tested by five subjects, compared standard piezoelectric respiratory belt. Each signal quantitatively qualitatively evaluated frequency domain to make sure no medical...
Fabric-based strain sensors have been developed using different technologies, among which flat knitting is one of the most effective and economical methods. However, knitted are not often used in practical applications because usually exhibit large elastic hysteresis when they deformed subjected to stress during application. One possible approach overcome these shortcomings introduce properties at yarn level by combining conductive materials with materials. In this paper, we demostrate a...
Abstract Background and Aims Cholangiocarcinoma (CCA) is a malignancy arising from biliary epithelial cells of intra‐ extrahepatic bile ducts with dismal prognosis few nonsurgical treatments available. Despite recent success in the immunotherapy‐based treatment many tumor types, this has not been successfully translated to CCA. Mucosal‐associated invariant T (MAIT) are cytotoxic innate‐like highly enriched human liver, where they located close proximity epithelium. Here, we aimed...
Textile based sensors were developed and used for remote monitoring of breathing. The breathing is simulated by using a new cyclic tester device. In the force applied along length textile sensor. However due to morphology human body, in real situation sensor not only under stretching but also certain degree bending. A prototype garment with situated on chest area was made. worn 10 persons, recorded as persons sitting still, walking jogging. Deep supine position method called athletic...
Liver-infiltrating T cells have been implicated in the pathogenesis of primary sclerosing cholangitis (PSC), however little information is available about changes other cellular compartments liver during PSC. This study aimed to characterize non-parenchymal intrahepatic PSC livers and find associations between phenotypes disease severity. Using immunohistochemistry, followed by automated image analysis quantification a principal component analysis, we studied PSC-patient (n = 17) controls...
Infection with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) can lead to disease increased morbidity and mortality among certain risk groups. The presence of autoantibodies against type I interferons (aIFN-Abs) is one mechanism that contributes 2019 (COVID-19).