A5065052372- Mobile Crowdsensing and Crowdsourcing
- Dementia and Cognitive Impairment Research
- Acute Myocardial Infarction Research
- Visual Attention and Saliency Detection
- Coronary Interventions and Diagnostics
- Antiplatelet Therapy and Cardiovascular Diseases
- Alzheimer's disease research and treatments
- Video Surveillance and Tracking Methods
- Chronic Disease Management Strategies
- Adipokines, Inflammation, and Metabolic Diseases
- Remote-Sensing Image Classification
- Cardiac Imaging and Diagnostics
- Genetic Neurodegenerative Diseases
- Medical Imaging and Pathology Studies
- Muscle Physiology and Disorders
- Cerebrovascular and genetic disorders
- Intracerebral and Subarachnoid Hemorrhage Research
- Human Mobility and Location-Based Analysis
- Anomaly Detection Techniques and Applications
- Blood properties and coagulation
- Retinal Diseases and Treatments
- Pharmaceutical Practices and Patient Outcomes
- Family and Patient Care in Intensive Care Units
- Diphtheria, Corynebacterium, and Tetanus
- Data-Driven Disease Surveillance
Austin Health
2015-2025
The University of Melbourne
2011-2025
Florey Institute of Neuroscience and Mental Health
2024
University of California, San Diego
2012-2021
Smith-Kettlewell Eye Research Institute
2021
Polytechnique Montréal
2007
Abstract Purpose Denosumab‐associated hypocalcaemia (DAH) has been reported in patients with osteoporosis or metastatic bone disease and is associated stages 4 5 chronic kidney (CKD, estimated glomerular filtration rate <30 mL/min/1.73m 2 ). Other risk factors for have not fully elucidated. We aimed to investigate the incidence of amongst receiving denosumab identify clinical features this adverse event. Methods Retrospective cohort study between June 2013 2014 administered (60/120 mg) at...
Inflammatory myofibroblastic tumors (IMTs) are characterized by myofibroblast proliferation and an inflammatory cell infiltrate. Little is known about the molecular pathways that precipitate IMT formation. Here, we report identification of somatic mutations in UPF1, a gene encodes essential component nonsense-mediated RNA decay (NMD) pathway, 13 15 pulmonary samples. The majority occurred specific region UPF1 triggered alternative splicing. Several mRNA targets NMD pathway were upregulated...
Massively parallel collaboration and emergent knowledge generation is described through a large scale survey for archaeological anomalies within ultra-high resolution earth-sensing satellite imagery. Over 10K online volunteers contributed 30K hours (3.4 years), examined 6,000 km2, generated 2.3 million feature categorizations. Motivated by the search Genghis Khan's tomb, participants were tasked with finding an enigma that lacks any historical description of its potential visual appearance....
Abstract Objectives Residential aged care respite clients are vulnerable and prone to poor health‐care outcomes. Improvements in the quality of for this cohort urgently needed. However, before proposing changes models, a nuanced understanding relevant issues affecting consumers professionals is required. We aimed explore perspectives consumers, carers, workers involved residential (RRC). Methods used purposive sampling recruit their family members, staff across metropolitan Melbourne...
Cerebral amyloid angiopathy (CAA) increases the risk of amyloid-related imaging abnormalities in Alzheimer's disease (AD) patients receiving anti-amyloid-beta therapies, emphasizing need to identify its factors. Data were collected from three cohort studies, and a machine learning model was developed predict CAA occurrence using selected The AD neuropathologic changes (ADNC)-CAA association significantly positive cross-sectional analysis. When stratified by factors, this generally stronger...
Patients with inherited retinal dystrophies (IRDs) were recruited from two understudied populations: Mexico and Pakistan as well a third well-studied population of European Americans to define the genetic architecture IRD by performing whole-genome sequencing (WGS). Whole-genome analysis was performed on 409 individuals 108 unrelated pedigrees IRDs. All patients underwent an ophthalmic evaluation establish phenotype. Although in this study had previously been examined for mutations known...
Background: Observational Alzheimer’s disease (AD) cohorts including the Australian, Biomarkers, Imaging and Lifestyle (AIBL) Study have enhanced our understanding of AD. The generalizability findings from AIBL to general population has yet be studied. Objective: We aimed compare characteristics people with AD dementia in 1) older Australians using pharmacological treatment for dementia, 2) who self-reported a diagnosis dementia. Methods: Descriptive study comparing aged 65 years over (1)...
A 34-year-old man presented with a 6-day history of diarrhoea, abdominal cramps and fever. Blood cultures were initially reported as positive for Escherichia coli using matrix-assisted laser desorption/ionisation time flight (MALDI-TOF) mass spectrometry. Contrast CT the abdomen pelvis revealed pancolitis terminal ileal thickening. The patient was treated empirically ampicillin, ciprofloxacin metronidazole. Stool Shigella sonnei . Subsequent testing on initial blood culture correctly...
The combination of crowdsourcing and high-resolution aerial satellite imagery have recently been explored in applications post-disaster damage assessment analytics. large scale distributed nature these tasks produce overwhelming amounts information that can be used to quickly assess damage. While provides fast, scalable analysis a disaster area, the accuracy or usefulness data collected is not well understood. This paper investigates variability limitations user as observed by standard...
The increasing prevalence of distributed human microtasking, crowdsourcing, has followed the exponential increase in data collection capabilities. large scale and nature these microtasks produce overwhelming amounts information that is inherently noisy due to input. Furthermore, inputs create a constantly changing dataset with additional added on daily basis. Methods quickly visualize, filter, understand this over temporal geospatial constraints key success crowdsourcing. This paper present...
The increasing power and decreasing size of mobile devices tablets provide a compelling new platform for field geographic information system (GIS) operations with geospatial datasets. As these data sets become increasingly larger more dynamic, it introduces the need real time analysis collection in field. Successful research digital age requires computing power, functionality, mobility. Location aware enable methods knowledge synthesis by merging physical virtual layers. dataset this study...
Left ventricular tissue Doppler imaging (TDI) velocities are used to monitor systolic and diastolic function, but it is not known how these may change in a hyperdynamic circulation, as often occurs anesthesia critical care medicine. Twenty-six healthy young volunteers were recruited left measured at rest, light exercise, strenuous recovery (10 minutes after exercise). At TDI significantly decreased from base apex (). Within basal, mid, apical sections, peak differed between segments (),...