Takeshi Okuda

ORCID: 0000-0001-8055-9434
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About
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Research Areas
  • Brain Metastases and Treatment
  • Glioma Diagnosis and Treatment
  • Gastric Cancer Management and Outcomes
  • Gastrointestinal Tumor Research and Treatment
  • Lung Cancer Research Studies
  • Lung Cancer Treatments and Mutations
  • Head and Neck Surgical Oncology
  • Metastasis and carcinoma case studies
  • Meningioma and schwannoma management
  • CNS Lymphoma Diagnosis and Treatment
  • Lymphoma Diagnosis and Treatment
  • Gastrointestinal disorders and treatments
  • Helicobacter pylori-related gastroenterology studies
  • Neuroscience and Neuropharmacology Research
  • Nanoplatforms for cancer theranostics
  • Cancer, Hypoxia, and Metabolism
  • Receptor Mechanisms and Signaling
  • Chronic Lymphocytic Leukemia Research
  • Sarcoma Diagnosis and Treatment
  • Eosinophilic Esophagitis
  • Clinical Nutrition and Gastroenterology
  • Glycosylation and Glycoproteins Research
  • Esophageal and GI Pathology
  • Microscopic Colitis
  • Gastroesophageal reflux and treatments

Kindai University
2015-2025

Kanazawa University
2021-2024

Osaka University
2023

Social Welfare Department
2021

Kansai Rosai Hospital
2019

Hyogo Medical University
2018

Kyoto University Hospital
2018

Osaka Prefecture University
2008

Nippon Medical School
1992-2007

Osaka Medical Center for Cancer and Cardiovascular Diseases
2005

Background/Aim: Excessive extracellular glutamate activates AMPA-type receptors (AMPA receptors) and induces seizures. Antagonistic activation of AMPA inhibits epilepsy glioma growth in vitro vivo studies. This study was conducted to evaluate the clinical impacts perampanel (PER), a novel receptor antagonist, on seizures tumor progression patients with uncontrollable epilepsy. Patients Methods: Twelve were treated PER. Seizure response, PER concentration, volume assessed. Results: Obvious...

10.21873/anticanres.12737 article EN Anticancer Research 2018-07-01

Background: Dementia is one the major problems of aging societies, and, novel and effective non-drug therapies are required as interventions in oldest-old to prevent cognitive decline. Objective: This study aims examine efficacy safety reminiscence using immersive virtual reality (iVR reminiscence) focusing on anxiety that often appears with The secondary objective reveal preference for VR image types reminiscence: live-action (LA) or computer graphics (CG). Methods: was a pilot, open-label,...

10.3389/fnhum.2020.598161 article EN cc-by Frontiers in Human Neuroscience 2021-01-18

To prevent cognitive decline, non-pharmacological therapies such as reminiscence for mild impairment (MCI) are required, however, the use of nursing homes was limited due to coronavirus disease 2019 (COVID-19). Therefore, demand remote-care is increasing. We hypothesized that immersive virtual reality (iVR) could be used more effectively than conventional anxiety. first examined effectiveness and safety using iVR (iVR session) in patients with MCI. After COVID-19 imposed restriction on...

10.1248/bpb.b21-00052 article EN Biological and Pharmaceutical Bulletin 2021-06-30

As for the surgical treatment of glioma, recent employment fluorescence-guided resection using 5-aminolevulinic acid (5-ALA) or high-dose fluorescein sodium has increased rate radical tumor resection. On other hand, there is no specific technique metastatic brain surgery. We have used a procedure with aid in surgery tumor. Fluorescein been 13 cases, and achieved effective stainability all cases. inexpensive, highly safe, comparatively easy to use, does not require any special equipment....

10.1055/s-2007-993200 article EN min - Minimally Invasive Neurosurgery 2007-12-01

Patients with malignant brain tumors are possibly at increased risk for surgical site infections (SSIs) considering the various medical situations associated disease. However, actual rate of SSI after tumor resection has not been well established, despite potential impact on patient outcome. To investigate incidence following surgery, we performed a retrospective study in 3 neurosurgical units. Subsequently, aiming reduction SSI, prospective using care bundle technique same The (n = 161) and...

10.2176/nmc.oa.2017-0034 article EN cc-by-nc-nd Neurologia medico-chirurgica 2017-01-01

✓ The authors report a case of hemichorea—hemiballism (HC-HB) that was successfully treated using deep brain stimulation (DBS). A 65-year-old right-handed man exhibited sudden onset right HC-HB without diabetic coma. At admission T 1 -weighted magnetic resonance (MR) images revealed high-intensity signal in the left striatum, contralateral to patient's involuntary movements. continued for 5 months after condition despite medical treatment and decreased intensity on MR images. patient...

10.3171/jns.2005.102.6.1137 article EN Journal of neurosurgery 2005-06-01

Glioblastoma multiforme (GBM) is a malignant brain tumor with an extremely poor prognosis. GBM tissues frequently express mesenchymal-epithelial transition factor (MET), which induces cell division, growth and migration. In addition, angiogenesis significant feature of GBM, attributable to the overexpression vascular endothelial (VEGF). Although VEGF inhibitor bevacizumab was recently highlighted as second-line drug for treatment, GBMs often recur even therapy. Based on these findings, we...

10.21873/anticanres.11767 article EN Anticancer Research 2017-07-05

In traditional practice patterns, physicians take care of all clinical decisions, such as diagnosis, treatment, and recovery. the Nippon Medical School Hospital a pathway for distal gastrectomy patients, recorded post-operative map, was introduced in August 2000. January 2001 management analyzed standardization carried out with printed order sets, drugs infusion solutions. The aim this study to evaluate significance patients by employing standardized postoperative sets. Patients methods:...

10.1272/jnms.70.263 article EN Journal of Nippon Medical School 2003-01-01

Calcifications within primary gastrointestinal tumors are rare. Gastrointestinal stromal tumor (GIST) is an unusual nonepithelial that develops in the tract. In this paper we describe a case of spurt bleeding from calcificated GIST stomach successfully treated by partial gastric resection. A 77-year-old man was admitted for chest discomfort and loss consciousness. Endoscopic examination revealed top submucosal tumor. No other lesions or points were found stomach. Emergency gastrectomy...

10.1272/jnms.72.304 article EN Journal of Nippon Medical School 2005-01-01

Chronic atrophic gastritis (CAG) is closely correlated with gastric cancer and predominant in Japan. Epidemiologically, food habits are the primary factor both CAG cancer. Two potential serum markers for have recently been investigated, i.e., concentration of pepsinogen (PG) presence antibodies against Helicobacter pylori. Serum PG I II I:PG ratio reported to be useful as indicators recurrent peptic ulcer screening patients at risk from In this study, we examined 483 by RIA (DAINABOT),...

10.1097/00004836-199312001-00026 article EN Journal of Clinical Gastroenterology 1993-12-01
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