A5076357376- Acute Ischemic Stroke Management
- Venous Thromboembolism Diagnosis and Management
- Cerebrovascular and Carotid Artery Diseases
- Traumatic Brain Injury and Neurovascular Disturbances
- Stroke Rehabilitation and Recovery
- Antiplatelet Therapy and Cardiovascular Diseases
- Lipoproteins and Cardiovascular Health
- Medical Case Reports and Studies
- Syphilis Diagnosis and Treatment
- Atrial Fibrillation Management and Outcomes
- Intracerebral and Subarachnoid Hemorrhage Research
North Estonia Medical Centre
2015-2025
Karolinska University Hospital
2015
Karolinska Institutet
2015
St. Anne's University Hospital Brno
2015
University Hospital Brno
2015
University of Glasgow
2015
Sapienza University of Rome
2015
Watford General Hospital
2015
Background and Purpose- A large infarct expanding cerebral edema (CED) due to a middle artery occlusion confers 70% mortality unless treated surgically. Reperfusion may cause blood-brain barrier disruption risk for secondary parenchymal hemorrhage (PH). We aimed investigate the effect of recanalization on development early CED PH after therapy. Methods- From SITS-International Stroke Treatment Registry, we selected patients with signs at baseline (either Hyperdense Artery Sign or computed...
The best reperfusion treatment for patients with mild acute ischaemic stroke harbouring proximal anterior circulation large vessel occlusion (LVO) is unknown. aim was to compare the safety and efficacy of intravenous thrombolysis (IVT) plus endovascular thrombectomy (EVT) versus IVT alone in LVO symptoms.From Safe Implementation Treatment Stroke-International Stroke Thrombolysis Thrombectomy Register (SITS-ISTR), were included: (i) consecutive patients, (ii) treated within 4.5 h from...
Objectives Intravenous thrombolysis (IVT) is contraindicated for acute ischemic stroke (AIS) patients taking direct oral anticoagulants (DOACs) within 48 hours before index stroke. Limited data exist on off‐label use of IVT these patients. We compared the safety and outcomes in AIS with DOAC treatment no OAC Methods analyzed from Safe Implementations Treatments Stroke (SITS) International Thrombolysis Registry during 2013–2024. Outcomes were symptomatic intracerebral hemorrhage (SICH) by...
Introduction: Data is limited on the safety of early initiation direct oral anticoagulation (DOAC) treatment after acute ischemic stroke (AIS) receiving reperfusion therapy in patients with atrial fibrillation (AF). We investigated timing DOAC and its association outcomes. Materials methods: included AIS AF diagnosis (prevalent or new) registered Safe Implementation Treatments Stroke international registry during 2013–2024. Safety outcomes were hemorrhage death. Secondary recurrent AIS, any...
<h3>Objective:</h3> To study the safety of off-label IV thrombolysis in patients with very severe stroke (NIH Stroke Scale [NIHSS] scores >25) compared (NIHSS 15–25), where treatment is within European regulations. <h3>Methods:</h3> Data were analyzed from 57,247 acute ischemic receiving tissue plasminogen activator 793 hospitals participating Safe Implementation Thrombolysis (SITS) International Registry (2002–2013). Eight hundred sixty-eight (1.5%) had NIHSS >25 and 19,995 (34.9%)...
Background and Purpose The influence of stroke etiology on outcomes after endovascular thrombectomy (EVT) is not well understood. We aimed to investigate whether subgrouped as large artery atherosclerosis (LAA) cardiac embolism (CE) influences in occlusion (LAO) treated by EVT.Methods included EVT LAO patients registered the Safe Implementation Treatment Stroke (SITS) register between January 1, 2014 September 3, 2019. Primary outcome was successful reperfusion (modified Cerebral Infarction...
Cerebral edema (CED) in ischemic stroke can worsen prognosis and about 70% of patients who develop severe CED die if treated conservatively. We aimed to describe incidence, risk factors outcomes with extensive ischemia. Oservational study based on Safe Implementation Treatments Stroke-International Stroke Treatment Registry (2003-2019). Severe hemispheric syndrome (SHS) at baseline persistent SHS (pSHS) 24 hours were defined as National Institutes Health Score (NIHSS) >15. Outcomes...
Statins have an important role in stroke prevention, especially high-risk populations and may also affect the initial severity outcomes patients taking them before ischemic stroke.Our aim was to evaluate association of statin pre-treatment with acute (AIS).We analyzed AIS received intravenous thrombolysis (IVT) and/or endovascular thrombectomy (EVT) recorded SITS International Thrombolysis Thrombectomy Registry from 2011 2017. We identified information at baseline. The primary outcome...
Seoses linnastumise ja HIV-nakkuse levikuga sageneb suufilisse haigestumine, tuues kaasa ka neurosuufilise esinemissageduse kasvu. Viimast soodustab suufilise varaste vormide diagnoosimata jaamine voi ebapiisav ravi. Haiguse sumptomid voivad olla neuroloogilised psuhhiaatrilised, sarnanedes teiste sageli esinevate haigustega nagu meningiit, transitoorne ajuisheemia, ajuinfarkt, Alzheimeri tobi jt. Artiklis on tutvustatud kuut juhtu, mida raviti aastatel 2001–2004 Pohja-Eesti...