- Air Quality and Health Impacts
- Air Quality Monitoring and Forecasting
- Particle Dynamics in Fluid Flows
- Nanoparticles: synthesis and applications
- Aerosol Filtration and Electrostatic Precipitation
- Occupational Health and Safety Research
- Coagulation and Flocculation Studies
- Vehicle emissions and performance
- Inhalation and Respiratory Drug Delivery
- Wind and Air Flow Studies
- Chemical Safety and Risk Management
- Healthcare and Environmental Waste Management
- Pigment Synthesis and Properties
- Atmospheric chemistry and aerosols
- Occupational exposure and asthma
- Microplastics and Plastic Pollution
- Indoor Air Quality and Microbial Exposure
- Noise Effects and Management
- Cyclone Separators and Fluid Dynamics
- Quality and Safety in Healthcare
- Radioactivity and Radon Measurements
- Ergonomics and Human Factors
- Risk and Safety Analysis
- X-ray Diffraction in Crystallography
- Nuclear and radioactivity studies
Institut National de Recherche et de Sécurité
2012-2023
Délégation Centre-Est
2014-2020
Institut de Veille Sanitaire
2011
Commissariat à l'Énergie Atomique et aux Énergies Alternatives
1997-2001
Institut de Radioprotection et de Sûreté Nucléaire
1998-2001
CEA Paris-Saclay
1997-2001
University of Cincinnati
1997-1998
Direction des énergies
1997
Université Paris Cité
1997
Université Paris-Est Créteil
1997
Potential differences in the toxicological properties of nanosized and non-nanosized particles have been notably pointed out for titanium dioxide (TiO(2)) particles, which are currently widely produced used many industrial areas. Nanoparticles iron oxides magnetite (Fe(3)O(4)) hematite (Fe(2)O(3)) also applications but their less documented than those TiO(2). In present study, vitro cytotoxicity genotoxicity commercially available microsized anatase TiO(2), rutile Fe(3)O(4), Fe(2)O(3) were...
Assessment of inhalable dust exposure requires reliable sampling methods in order to measure airborne particles’ concentrations. Many aerosol samplers can be used but their performances widely vary and remain unknown some cases. The performance is strongly dependent on particle size ambient air velocity. Five have been studied two laboratory wind tunnels using polydisperse glass-beads’ test aerosol. Samplers tested were IOM sampler (UK), versions CIP 10-I sampler, v1 v2 (F), 37-mm closed...
Comparison of DiSCmini data to reference for polydisperse test aerosols in terms diameter, number concentration and alv-LDSA.
High concentrations of bioaerosols containing bacterial, fungal and biotoxinic matter are encountered in many workplaces, e.g. solid waste treatment plants, water plants sewage networks. A personal bioaerosol sampler, the CIP 10-M (M-microbiologic), has been developed to measure worker exposure airborne biological agents. This sampler is battery operated; it light easy wear offers full work shift autonomy. It can sample much higher than impactors limits mechanical stress on microorganisms....
While personal aerosol samplers have been characterized primarily based on wind tunnel tests conducted at relatively high speeds, modern indoor occupational environments are usually represented by very slow moving air. Recent surveys suggest that elevated levels of exposure to inhalable airborne particles typically observed when the worker, operating in vicinity dust source, faces source. Thus, first objective this study was design and test a new, low cost experimental protocol for measuring...
A comparison between various methods for real-time measurements of lung deposited surface area (LDSA) using spherical particles and powder dust with specific ranging from 0.03 to 112 m2 g–1 was conducted. LDSA concentrations measured directly Nanoparticle Surface Area Monitor (NSAM) Aerotrak were compared recalculated size distribution Electrical Low Pressure Impactor (ELPI) Fast Mobility Particle Sizer (FMPS). FMPS ELPI also estimated gravimetrical filter areas. Measurement showed very good...
Concern has been raised about the potential impact of nanomaterials exposure on human health, and France decided to implement a timely epidemiological surveillance tool workers likely be exposed engineered that could accompany development nanotechnologies.A comprehensive review toxicological literature conducted together with an exploratory study among French companies producing or handling nanoobjects.A double system is proposed consisting prospective cohort survey repeated cross-sectional...
The number of workers potentially exposed to nanoparticles (NPs) in industrial processes is constantly increasing, even though the toxicological effects these compounds have not yet been fully characterized. hazards associated with this exposure can be assessed most relevantly by toxicology studies involving inhalation nanoaerosols animals. In paper, we describe and characterize an aerosol generated a nose-only system used study respiratory NPs rat; was designed meet stringent requirements...
We demonstrate the relevance of Volume Specific Surface Area (VSSA) parameter to identify nanoparticulate character powder mixes based on either spherical constituent particles with bimodal size distributions (TiO
Several samplers (IOM, CIP 10-I v1, ACCU-CAP, and Button) were evaluated at various wood industry companies using the CALTOOL system. The results obtained show that compared to mouth, which can be considered representative of exposure a person placed same location under experimental conditions, concentrations measured by IOM, ACCU-CAP are not significantly different (respectively, 1.12, 0.94, 0.80 1.00), Button sampler (0.86) being close sampler. Comparisons dust both closed-face cassette...
This work aims at presenting a nanoparticle generation non-transportable facility in aerosol phase called "CAIMAN" (acronym for Characterization of Instruments Measuring Aerosols Nanoparticles) and its performances. delivers primary nanoaerosols from electrodes made C, Al, Cu (and mixtures containing Be), Ag, Constantane (a mixture Cu-55wt% Ni-45wt%) particles known concentrations, sizes, shapes mean charge levels. It is also capable to deliver well-known particle combinations the "primary"...
Cascade impactors are widely used to provide particle size distributions for the study of aerosols in workplaces and ambient air. In frame exposure assessment airborne particles, one their main advantages is possibility perform further off-line analysis (e.g. electron microscopy, physical-chemical characterization by XRD, ICP-MS, etc.) on collected samples according size. However, large channel width makes not enough size-resolved. Furthermore, spite sharpness collection efficiency curves,...
Nanoparticulate powders are increasingly found in the workplace. Inhalation exposure to airborne nanoparticles (NPs) is possible throughout life-cycle of powders. As toxicity NPs has never been demonstrated, it remains essential evaluate risks associated with order propose preventative measures. The first step a risk assessment strategy consists identification 'nano' nature material, which suffers from lack an operational methodology. Here, we present simplified and relying on volume...
The relatively recent development of industries working with nanomaterials has created challenges for exposure assessment. In this article, we propose a simple approach to assessing nanomaterial exposures the purposes epidemiological studies workers in these industries. This method consists an onsite industrial hygiene visit facilities carried out individually and description workstations where nano-objects their agglomerates aggregates (NOAA) are present using standardized tool, Onsite...
This work shows that the volume specific surface area could be a reliable criterion for nanomaterial identification.