A5001854472- Obstructive Sleep Apnea Research
- Neuroscience of respiration and sleep
- Neonatal Respiratory Health Research
- Tracheal and airway disorders
- Sleep and related disorders
- Cleft Lip and Palate Research
- Craniofacial Disorders and Treatments
- Child Nutrition and Feeding Issues
- Restless Legs Syndrome Research
- Sleep and Wakefulness Research
- Cystic Fibrosis Research Advances
- Children's Physical and Motor Development
- Antibiotic Resistance in Bacteria
- Inhalation and Respiratory Drug Delivery
- Medical Imaging and Pathology Studies
- Congenital Diaphragmatic Hernia Studies
- Respiratory Support and Mechanisms
- Oral and Craniofacial Lesions
- Diversity and Career in Medicine
- Healthcare professionals’ stress and burnout
- Pediatric health and respiratory diseases
- Cardiovascular and Diving-Related Complications
- Congenital Heart Disease Studies
- Genetics and Neurodevelopmental Disorders
- Airway Management and Intubation Techniques
University of Tehran
2025
Children's Mercy Hospital
2016-2024
University of Missouri–Kansas City
2018-2024
United States University
2023
In-Q-Tel
2023
GTx (United States)
2023
Mercy Hospital
2017-2021
Cincinnati Children's Hospital Medical Center
2014-2020
Children's Medical Center
2017
University of Cincinnati
2014-2015
Rationale: The vast majority of children around the world undergoing adenotonsillectomy for obstructive sleep apnea–hypopnea syndrome (OSA) are not objectively diagnosed by nocturnal polysomnography because access availability and cost issues. Automated analysis oximetry (nSpO2), which is readily globally available, could potentially provide a reliable convenient diagnostic approach pediatric OSA.Methods: Deidentified nSpO2 recordings from total 4,191 originating 13 laboratories were...
The COVID-19 pandemic led to widespread use of telemedicine and highlighted its importance in improving access sleep care advocating for health. This update incorporates the lessons learned from such utilization telehealth build on American Academy Sleep Medicine's 2015 position paper diagnosing treating disorders. Important key factors this include an emphasis quality value, privacy safety, health advocacy through telemedicine, future directions.
Abstract Objective To develop an expert consensus statement regarding persistent pediatric obstructive sleep apnea (OSA) focused on quality improvement and clarification of controversies. Persistent OSA was defined as after adenotonsillectomy or tonsillectomy when adenoids are not enlarged. Methods An panel clinicians, nominated by stakeholder organizations, used the published methodology from American Academy Otolaryngology‐Head Neck Surgery to statements for a target population children...
Culture and sequencing have produced divergent hypotheses about cystic fibrosis (CF) lung infections. Culturing suggests that CF lungs are uninfected before colonization by a limited group of pathogens. Sequencing diverse communities mostly oral bacteria inhabit early on diversity decreases as disease progresses. We studied the microbiota children using bronchoscopy sequencing, with measures to reduce contamination. found no evidence for bacterial in lavages lacked Lavage microbial varied...
Pierre Robin sequence (PRS)-related airway obstruction is often treated surgically; however, objective measures predicting the need for surgery are poorly defined.A retrospective chart review was performed on 171 neonates with PRS. Infants were grouped based upon intervention modality: nonsurgical (conservative) or surgical [mandibular distraction osteogenesis (MDO) tracheostomy]. Demographic data, physical examination findings, and study results compared between groups to determine risk...
Summary Objective The prevalence of obstructive sleep apnea (OSA) is higher in children with poorly controlled asthma. We aimed to determine the validity Pediatric Sleep Questionnaire (PSQ) screen for OSA Methods This retrospective review encompassed studies and medical records asthmatic evaluated center at CCHMC over 13 years. Measures were calculated using various cut‐off values apnea‐hypopnea index (OI; >1, >2, >5) PSQ scores (>0.33, >0.5). Correlation between OI,...
Obstructive sleep apnea (OSA) is the most common sleep-related breathing disorder. Although adenotonsillectomy first-line management for pediatric OSA, up to 40% of children may have persistent OSA. This document provides an evidence-based clinical practice guideline on with The target audience clinicians, including physicians, dentists, and allied health professionals, caring
Although Pierre Robin sequence (PRS) is a major cause of neonatal obstructive sleep apnea (OSA), longitudinal studies reporting evolution with age are lacking. This study aimed to describe changes in sleep-related respiratory parameters and architecture neonates PRS treated conservatively (defined for this paper as treatment without tracheostomy or mandibular distraction).A retrospective, 14-year, single-institution who underwent diagnostic polysomnography (PSG) at least one follow-up PSG....
Background: Robin sequence is a common cause of upper airway obstruction in newborns. Herein, we report sleep outcomes neonates undergoing external mandibular distraction osteogenesis. Methods: In this retrospective, 14-year, single-institution study with osteogenesis, compare respiratory parameters and architecture before versus after surgery. Results: Thirty-one were included; age was 13 days (interquartile range, 5 to 34 days) at preoperative polysomnography 80 50 98 postoperative...
Abstract Pulmonary interstitial glycogenosis (PIG) is an idiopathic lung disease of infants. The underlying pulmonary pathophysiology PIG has not been well characterized. Herein we report a term‐gestatation infant who presented with persistent tachypnea and hypoxia. A chest CT scan demonstrated diffuse ground glass appearance biopsy increased alveolar septae cellularity glycogen‐containing cells, consistent diagnosis PIG. At 3 months age, function testing included: pre‐ post‐bronchodilator...
There is limited evidence on the accuracy of oximetry in evaluation infant obstructive sleep apnea (OSA). We aimed to determine utility overnight stratify infants at risk for OSA, urgency definitive screening with an in-laboratory polysomnogram (PSG).Retrospective single-institution cohort study undergoing PSG and a separate over 8-year period. Correlations, using both in-hospital (attended) or at-home (unattended) settings, ODI410 (decrease oxygen saturation ≥ 4% from baseline, duration 10...