- Air Quality and Health Impacts
- Climate Change and Health Impacts
- Noise Effects and Management
- Indoor Air Quality and Microbial Exposure
- Air Quality Monitoring and Forecasting
- Lower Extremity Biomechanics and Pathologies
- Sports Performance and Training
- Chronic Obstructive Pulmonary Disease (COPD) Research
- Occupational exposure and asthma
- Allergic Rhinitis and Sensitization
- Sports injuries and prevention
- Asthma and respiratory diseases
- Occupational and environmental lung diseases
- Cardiac Health and Mental Health
- Effects and risks of endocrine disrupting chemicals
- Medical Imaging Techniques and Applications
- Rheumatoid Arthritis Research and Therapies
- Cardiac Imaging and Diagnostics
- Pediatric health and respiratory diseases
- Transplantation: Methods and Outcomes
- Heart Rate Variability and Autonomic Control
- Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
- Workplace Health and Well-being
- 3D Shape Modeling and Analysis
- Employment and Welfare Studies
National Taiwan University Hospital
2014-2024
National Taiwan University
2014-2024
University of Taipei
2020-2023
Ten Chen Hospital
2017
Lee University
2017
State Administration of Foreign Experts Affairs
2017
Taipei Medical University
2006-2013
Changhua Christian Hospital
2013
Wan Fang Hospital
2006-2011
Tzu Chi University
2010
Background The World Health Organization has projected that by 2030, chronic obstructive pulmonary disease (COPD) will be the third-leading cause of mortality and seventh-leading morbidity worldwide. Acute exacerbations (AECOPD) are associated with an accelerated decline in lung function, diminished quality life, higher mortality. Accurate early detection acute enable management reduce Objective aim this study was to develop a prediction system using lifestyle data, environmental factors,...
Abstract Impaired lung function is associated with morbidity and mortality in the elderly. However, there a paucity of data regarding long-term effects particulate matter (PM) on among This study evaluated exposure-response relationship between ambient PM different indices elderly Taiwan. A cross-sectional survey individuals aged ≥65 years was conducted Taiwan from October 2015 to September 2016. Those who attended annual health examination for five hospitals varying background...
Objective: To investigate a new style of resistance exercise using elastic bands and explore its therapeutic effect on the lower-extremity function female patients with osteoarthritis (OA) knee. Design: A randomized, controlled clinical trial. Setting: University-affiliated medical center. Participants: Forty-one women mild-to-moderate knee OA were randomly assigned to one two groups, an group (n = 24; age: 65.0 ± 8.4 years), control 17; 70.8 years). Interventions: The performed supervised...
Abstract Loss of skeletal muscle mass is common with aging and can cause morbidity mortality in the elderly. The effects particulate air pollution on not known. study aims to assess chronic ambient fine particulates (PM 2.5 ) body composition From October 2015 November 2016, a cross-sectional survey 530 elderly (age > = 65 years) was conducted Taipei Basin, Taiwan. measured by bioelectrical impedance analysis (InBody 120). One year exposure estimated using Kriging method at participant’s...
Abstract Background Some evidences have shown the association between air pollution exposure and development of interstitial lung diseases. However, effect on progression restrictive ventilatory impairment diffusion capacity reduction is unknown. This study aimed to evaluate effects long-term ambient change rates total capacity, residual volume, among elderly. Methods From 2016 2018, single-breath helium dilution with carbon monoxide was performed once per year 543 elderly individuals....
<h3>Rationale and objectives</h3> Obliterative bronchiolitis (OB) is a rare disease with small number of established occupational aetiologies. We describe case series severe OB in workers making glass-reinforced plastics. <h3>Methods</h3> Workplace exposures were the likely cause after independent diagnosis two laying up fibreglass hulls yachts; second worker took over job first he left following lung transplant. Presentation these cases at international meetings led to others identifying...
Background Left atrial ( LA ) dysfunction, expressed as impaired deformation using two‐dimensional (2D) strain imaging, has been observed in association with rheumatic mitral stenosis MS ). However, the clinical role of speckle tracking echocardiography STE )‐derived rarely studied . Aim This study aimed to identify determinants New York Heart Association NYHA functional class patients and investigate relationship between left measured by ‐derived heart failure symptoms. Methods Sixty‐nine...
Abstract Background Childhood asthma is a common disease whose prevalence changing. Shift in environmental exposure was one of the plausible explanations. This study investigated changes association between childhood and ambient air pollution occurring over time. Method A nationwide questionnaire survey concerning respiratory illness symptoms administered to Taiwanese elementary middle school students 2011 repeatedly 2016‐2017. During period, concentrations pollutants were obtained from...
Background Evidence suggests differences in clinical characteristics, causes, and prognoses between heart failure with reduced ejection fraction ( HF r EF ) preserved (HFpEF). Most studies have failed to support the prognostic relevance of anxiety or unclassified mean left ventricular <40%. Meanwhile, association p remains unexamined. This study compared value . Methods Results A total 158 patients (left fraction=28.51±7.53%) 108 HFpEF fraction=64.53±9.67%) were recruited May 2012 December...
Scatter and spatial resolution effects degrade the accuracy of radioactivity concentration estimates obtained from positron emission tomography (PET) data. We present evaluate a methodology for region quantification which accounts these degradations. The method is based on analysis sinogram data does not require dynamic sequences to be reconstructed. Moreover, variance are also produced may used define weights model analyses that use weighted least squares minimization in order obtain...
Chen, Chi-Hsien, Yuh-Feng Liu, Shin-Da Lee, Wen-Chih Ying-Lan Tsai, Chien-Wen Hou, Chih-Yang Huang, and Chia-Hua Kuo. Altitude hypoxia increases glucose uptake in human heart. High Alt. Med Biol. 10:83–86, 2009.—Cardiac muscle is a highly oxygenated tissue that produces ATP mainly from fat oxidation. However, when the rate of oxygen demand exceeds supply, energy reliance on carbohydrate substrate becomes crucial for sustaining normal cardiac function. In this study, effect acute altitude...
The validity and reliability of the Optojump system were investigated for jumping height flight time in vertical jump tests. Conversely, purpose present study was to investigate measuring contact lateral displacement change direction Thirty basketball collegiate athletes tested on two 10 m sprints with a 60° (COD60) or 180° (COD180) direction, controlled (CLRJ) maximal (MLRJ) rebound jump, countermovement (LCMJ) squat (LSJ) concomitant use force plates measurement COD60, COD180, CLRJ, MLRJ,...
Abstract Background Occupational exposure to artificial stone, a popular material used for countertops, can cause accelerated silicosis, but the precise relationship between silica dose and disease development is unclear. Objectives This study evaluated impact of on lung function chest imaging in stone manufacturing workers. Methods Questionnaire spirometry assessments were administered workers two plants. A high-exposure subset underwent further evaluation, including CT DLco. Weighting...
We conducted a pilot study of the feasibility an Internet-based weight loss programme using videoconferencing to emulate face-to-face situations and Web service support self-monitoring. A pre–post test design was used compare changes in bodyweight, metabolic variables attendance rate. Nine subjects lost on average 5.9 kg (6.0% body weight, P<0.001) over course 12-week programme. Waist circumference reduced significantly (10.2 cm, P=0.03). Total cholesterol, aspartate transferase (AST)...