Dahai Gu

ORCID: 0000-0001-8103-7697
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Research Areas
  • Animal Nutrition and Physiology
  • Genetic and phenotypic traits in livestock
  • Meat and Animal Product Quality
  • Biochemical Analysis and Sensing Techniques
  • Cancer-related molecular mechanisms research
  • Livestock and Poultry Management
  • Genomics and Phylogenetic Studies
  • Biochemical effects in animals
  • RNA and protein synthesis mechanisms
  • Protein Hydrolysis and Bioactive Peptides
  • Advanced Chemical Sensor Technologies
  • melanin and skin pigmentation
  • Muscle Physiology and Disorders
  • Chromosomal and Genetic Variations
  • Invertebrate Immune Response Mechanisms
  • Food Quality and Safety Studies
  • Antimicrobial Peptides and Activities
  • Adipose Tissue and Metabolism
  • Animal Genetics and Reproduction
  • Microbial Metabolism and Applications
  • Aquaculture Nutrition and Growth
  • Olfactory and Sensory Function Studies
  • Reproductive biology and impacts on aquatic species
  • Bee Products Chemical Analysis
  • Genetic Mapping and Diversity in Plants and Animals

Yunnan Agricultural University
2013-2024

The growth hormone / insulin-like factor-1 (GH/IGF-1) pathway of the somatotropic axis is major controller for rate and body size in vertebrates, but effect selection on expression GH/IGF-1 genes their association with performance farm animals not fully understood. We analyzed a time series profiles two chicken breeds, Daweishan mini chickens Wuding chickens, commercial Avian broilers hybrid exhibiting markedly different sizes rates. found that feed conversion efficiency were significantly...

10.1371/journal.pone.0195378 article EN cc-by PLoS ONE 2018-04-09

Melanin is an important antioxidant in food and has been used medicine cosmetology. Chicken meat with high melanin content from black-boned chickens have considered a nutritious potential medicinal properties. The molecular mechanism of melanogenesis skeletal muscle remain poorly understood. This study investigated the biological gene-metabolite associations regulating pathways Wuliangshan two normal boned chicken breeds as control.We identified 25 differentially expressed genes 11...

10.1186/s12864-022-08388-w article EN cc-by BMC Genomics 2022-03-02

Abstract Many lines of evidence indicate that red jungle fowl (RJF) is the primary ancestor domestic chickens. Although multiple versions RJF (galgal2-galgal5 and GRCg6a) commercial chickens (GRCg7b/w Huxu) genomes have been assembled since 2004, no high-quality indigenous chicken assembled, hampering understanding domestication evolution. To fill gap, we sequenced four with distinct morphological traits in southwest China, using a combination short, long Hi-C reads. We each genome (~1.0 Gb)...

10.1038/s41597-024-03126-1 article EN cc-by Scientific Data 2024-03-15

Myostatin is a negative regulator of skeletal muscle growth. Muscle tissue the largest in body and influences Commercial Avian broiler chickens are selected for high growth rate muscularity. Daweishan mini slow growing small-sized chicken breed. We investigated relations between (breast leg) myostatin mRNA expression Twenty per breed were slaughtered at 0, 30, 60, 90, 120, 150 days age. Body weights higher all times chickens. Breast was than day 30. peaked 60 remained breast muscle....

10.1007/s11033-018-4187-7 article EN cc-by Molecular Biology Reports 2018-05-08

Chicken soup is popular among consumers because of its delicious taste, strong flavor, and abundant nutritional value. Twenty-four Yunnan local hens were stewed by adding different amounts NaCl [1.5, 2, 2.5, 3%, m/m, calculated based on chicken carcass weight; chicken: water = 1:2 (m/m)] to study the effect salt addition taste- flavor-related compounds in soup. Sensory evaluation results showed that 2 2.5% treatment groups had higher scores. Water-soluble small molecule detected LC-Q/TOF-MS...

10.3389/fnut.2024.1368789 article EN cc-by Frontiers in Nutrition 2024-03-13

Although many studies have been done to reveal artificial selection signatures in commercial and indigenous chickens, a limited number of genes linked specific traits. To identify more trait-related genes, we re-sequenced total 85 individuals five chicken breeds with distinct traits from Yunnan Province, China.

10.1186/s12864-024-10291-5 article EN cc-by BMC Genomics 2024-04-30

Myostatin (MSTN) is expressed in the myotome and developing skeletal muscles, acts to regulate number of muscle fibers.Wuding chicken large body, developed muscle, high disease resistance, tender, delicious meat, are not selected for fast growth.Broiler chickens (Avian broiler) growth have a body size mass.Here, 240 one-dayold (120 Wuding 120 broilers) were examined.Twenty from each breed sacrificed at days 1, 30, 60, 90, L.X. Liu et al.Genetics Molecular Research 15 (4): gmr15048967 120,...

10.4238/gmr15048967 article EN Genetics and Molecular Research 2016-01-01

Intensive selection has resulted in increased growth rates and muscularity broiler chickens, addition to adverse effects, including delayed organ development, sudden death syndrome, altered metabolic rates. The biological mechanisms underlying responses remain largely unknown. Non-artificially-selected indigenous Chinese chicken breeds display a wide variety of phenotypes, differential rate, body weight, muscularity. Wuding breed is fast growing large breed, the Daweishan mini slow small...

10.1186/s12864-017-3845-9 article EN cc-by BMC Genomics 2017-06-20

Summary The chicken broth was pre‐treated with ultrasound at 0, 480, 600, 720 and 840 W for 30 min before stewing, the changes of free fatty acids, small molecular compounds, volatile flavour umami polypeptides in were determined by GC–MS, UPLC‐Q‐Exactive‐MS, GC–IMS LC–MS/MS, respectively. 600 ultrasonic treatment group outperformed other groups terms sensory evaluation ( P < 0.05). Palmitic acid stearic chief acids broth. 530 236 molecule metabolites found. 36 compounds identified broth,...

10.1111/ijfs.16560 article EN International Journal of Food Science & Technology 2023-06-20

Although multiple chicken genomes have been assembled and annotated, the numbers of protein-coding genes in their variation among breeds are still uncertain due to low quality these genome assemblies limited resources used gene annotations. To fill gaps, we recently four indigenous with distinct traits at chromosome-level. In this study, annotated each using a combination RNA-seq- homology-based approaches.

10.1186/s12864-024-10316-z article EN cc-by BMC Genomics 2024-05-01

Abstract Arginine (Arg) is an important essential amino acid required for optimum fish growth. However, its role in plant‐rich diets on growth and the level juvenile Hemibagrus wyckioides are currently unknown. This study evaluated effects of Arg supplementation growth, feed utilization, whole body composition, blood biochemical indicators gene expressions target rapamycin (TOR) signaling pathway H. . A total 450 (6.40 ± 0.06 g) were randomized into six equal groups fed with graded levels: 0...

10.1111/jwas.12748 article EN cc-by Journal of the World Aquaculture Society 2020-10-12

Chicken skeletal muscle satellite cells are located between the basement membrane and sarcolemma of mature fibers.Avian broilers have been genetically selected based on their high growth velocity large mass.The Wuding chicken is a famous local in Yunnan Province that undergoes non-selection breeding slow growing.In this study, we aimed to explore differences proliferation differentiation properties isolated from two breeds.Using immunofluorescence, Genetics Molecular Research 15 (4):...

10.4238/gmr.15048815 article EN Genetics and Molecular Research 2016-01-01

Host defense peptides (HDPs) are an important first line of with antimicrobial and immunomodulatory properties. Selection for increased body weight is hypothesized to be related reduced immune response. We studied the relationships among weight, age, HDP expression patterns in intestine organs. used chickens marked differences sizes. The non-selected Daweishan mini showed highest indexes organs lowest concentrations plasma parameters C3, C4, IgA, IgY, while commercial Avian broiler opposite...

10.1371/journal.pone.0238675 article EN public-domain PLoS ONE 2020-12-28

Abstract Background Although multiple chicken genomes have been assembled and annotated, the number of protein-coding genes in is still uncertain due to low quality these genome assemblies limited resources used gene annotations. Results To fill gap, we annotated our four recently high-quality indigenous chickens with distinct traits using a combination RNA-seq- homology-based approach. Our recovered 51 274 “missing” birds general 36 174 particular. Intriguingly, based on deeply sequenced...

10.1101/2024.01.08.574549 preprint EN cc-by-nc bioRxiv (Cold Spring Harbor Laboratory) 2024-01-09
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