A5100454354- Air Quality and Health Impacts
- Climate Change and Health Impacts
- Pituitary Gland Disorders and Treatments
- Glioma Diagnosis and Treatment
- Global Health Care Issues
- Heart Failure Treatment and Management
- Aquaculture disease management and microbiota
- Cardiovascular Function and Risk Factors
- Aquaculture Nutrition and Growth
- Diabetes Treatment and Management
- Renal Diseases and Glomerulopathies
- Liver Disease Diagnosis and Treatment
- Adrenal and Paraganglionic Tumors
- Energy, Environment, Economic Growth
- Obesity, Physical Activity, Diet
- Hearing, Cochlea, Tinnitus, Genetics
- Nutritional Studies and Diet
- Physiological and biochemical adaptations
- Health Systems, Economic Evaluations, Quality of Life
- Plant Molecular Biology Research
- Genetic Mapping and Diversity in Plants and Animals
- Aquatic Ecosystems and Phytoplankton Dynamics
- Ferroptosis and cancer prognosis
- Air Quality Monitoring and Forecasting
- Constructed Wetlands for Wastewater Treatment
Shanxi Agricultural University
2025
Beijing Academy of Agricultural and Forestry Sciences
2022-2025
Qingdao University
2019-2025
Nanjing University of Chinese Medicine
2024-2025
Zunyi Medical University
2022-2025
Tianjin University of Traditional Chinese Medicine
2025
Soochow University
2025
First Affiliated Hospital of Soochow University
2025
Nantong University
2025
Taizhou People's Hospital
2025
Background Evidence of the short-term effects ambient air pollution on risk ischemic stroke in low- and middle-income countries is limited inconsistent. We aimed to examine associations between daily hospital admissions for China. Methods findings identified 2014–2016 from national database covering up 0.28 billion people who received Urban Employee Basic Medical Insurance (UEBMI) examined admission using a two-stage method. Poisson time-series regression models were firstly fitted estimate...
The authors previously described a graded approach to skull base repair following endonasal microscopic or endoscope-assisted tumor surgery. In this paper they review their experience with reconstruction in the endoscopic era.
Abstract Objective To estimate the risks of daily hospital admissions for cause specific major cardiovascular diseases associated with short term exposure to ambient fine particulate matter (aerodynamic diameter ≤2.5 μm; PM 2.5 ) pollution in China. Design National time series study. Setting 184 cities Population 8 834 533 causes Chinese recorded by national database Urban Employee Basic Medical Insurance from 1 January 2014 31 December 2017. Main outcome measures Daily counts city primary...
Abstract Background Polypharmacy is one of the most important health issues for its potential impacts on disease burden and healthcare costs. The aim this study was to update a comprehensive picture prevalence trends in polypharmacy over 20 years U.S. adults. Methods Participants included 55,081 adults aged ≥ from National Health Nutrition Examination Survey, January 1, 1999, through December 31, 2018. simultaneously use 5 drugs individual defined as polypharmacy. were evaluated among within...
Background Epidemiological studies have provided compelling evidence of associations between ambient temperature and cardiovascular disease. However, effects daily variability on disease is scarce mixed. We aimed to examine short-term hospital admissions for cause-specific in urban China. Methods findings conducted a national time-series analysis 184 cities China 2014 2017. Data ischemic heart disease, failure, rhythm disturbances, stroke were obtained from the database Urban Employee Basic...
Abstract Purpose: Pituitary adenomas are one of the most common benign neoplasms central nervous system. Although emerging evidence suggests roles for both genetic and epigenetic factors in tumorigenesis, degree to which these contribute disease remains poorly understood. Experimental Design: A multiplatform analysis was performed identify genomic epigenomic underpinnings among three major subtypes surgically resected pituitary 48 patients: growth hormone (GH)–secreting (n = 17),...
Background The effects of ambient particulate matter (PM) pollution on pneumonia in adults are inconclusive, and few scientific data a national scale have been generated low- or middle-income countries, despite their much higher PM concentrations. We aimed to examine the association between levels hospital admissions for Chinese adults. Methods findings A nationwide time series study was conducted China 2014 2017. Information daily 2014–2017 collected from database Urban Employee Basic...
To more fully assess the far-reaching effects of fossil fuel combustion on humanity, it is necessary to gain an in-depth understanding full impact fuels human health and lifetime potential. However, current knowledge long-term consequences use damage in early life, such as capital impacts adulthood, still insufficient. This paper aims summarize evidence fuel-driven air pollution climate change children consequent effect stemming from these damages. Evidence indicates that not only...
The photolysis of tetrabromobisphenol A (TBBPA) in aqueous solution under simulated solar light irradiation was studied different conditions to find out mechanisms and pathways that control the transformation TBBPA during photoreaction. Particular attention paid identification intermediates elucidation mechanism by UPLC, LC/MS, FT-ICR-MS, NMR, ESR, stable isotope techniques (13C 18O). results showed could occur both aerated deaerated conditions. magnetic effect (MIE)-hydrolysis proposed as...
Abstract Background Thyroid hormone receptor interactor 13 (TRIP13) is an AAA + ATPase that plays important role in the mitotic checkpoint. TRIP13 highly expressed various human tumours and promotes tumorigenesis. However, biological effect of GBM cells remains unclear. Methods We generated cell models with overexpressed or silenced via lentivirus-mediated overexpression RNAi methods. The proliferation, migration invasion has been further explored. Results Our research indicated was tissues...
Few large multicity studies have assessed acute effect of tropospheric ozone pollution on pneumonia risk. We aimed to examine the relation between day-to-day changes in concentrations and hospital admissions for China. conducted a national time-series study 184 major Chinese cities from 2014 2017. City-specific was evaluated using an over-dispersed generalized additive model. Random-effects meta-analysis pool city-specific estimates. Two-pollutant models were fitted test robustness...
To explore the approaches and diagnostic yield of genetic testing for renal disease in children, we describe genotype phenotype national cohort children with from 13 different regions China recruited 2014 to 2018 by building up multicenter registration system (Chinese Children Genetic Kidney Disease Database, CCGKDD). diagnosis was confirmed 42.1% our 1001 pediatric patients clinical suspicion a disease. Of 106 distinct monogenetic disorders detected, 15 accounted 60.7% diagnoses. The 29.1%...
Acute kidney injury (AKI) is a common complication of critically ill adult patients with COVID-19. However, currently, no studies investigate impairment in children We investigated incidence and treatment AKI pediatric COVID-19 Wuhan Children's Hospital during the early stages pandemic discuss possible mechanisms related to SARS-CoV-2 infection.
Abstract Background Tropical stenothermal fish exhibit special tolerance and response to cold stress. However current knowledge of the molecular mechanisms stress in aquatic ectotherms is largely drawn from eurythermal or extreme species. The tiger barb Puntius tetrazona a tropical fish, with great popularity aquarium trade research. Results To investigate mechanism P. low temperature, were exposed increasing levels acute Histopathological analysis showed that brain, gill, liver muscle...
Background: Knee osteoarthritis (KOA) provides many challenges on the healthcare system. However, few studies have reported epidemiology, particularly in a large population. Our study aimed to estimate prevalence, incidence, trends, and patterns of diagnosed KOA China. Methods: This was longitudinal study. We used health insurance claims 17.7 million adults from 2008–2017 identify people with KOA. Trends prevalence incidence were analyzed using joinpoint regression. Results: identified...
The CACHE challenges are a series of prospective benchmarking exercises to evaluate progress in the field computational hit-finding. Here we report results inaugural challenge which 23 teams each selected up 100 commercially available compounds that they predicted would bind WDR domain Parkinson's disease target LRRK2, with no known ligand and only an apo structure PDB. lack binding data presumably low druggability is hit finding methods. Of 1955 molecules by participants Round 1 challenge,...
Aficamten, a next-in-class cardiac myosin inhibitor, improved peak oxygen uptake (pVO2) and lowered resting Valsalva left ventricular outflow (LVOT) gradients in adults with symptomatic obstructive hypertrophic cardiomyopathy (oHCM) SEQUOIA-HCM (Phase 3 Trial to Evaluate the Efficacy Safety of Aficamten Compared Placebo Adults With Symptomatic oHCM), phase 3, multicenter, randomized, double-blinded, placebo-controlled study. The authors sought evaluate effect aficamten on echocardiographic...