A5056976214- Spinal Cord Injury Research
- Child Abuse and Trauma
- Stroke Rehabilitation and Recovery
- Cerebral Palsy and Movement Disorders
- Child Abuse and Related Trauma
- Emergency and Acute Care Studies
- Homicide, Infanticide, and Child Abuse
- Pneumonia and Respiratory Infections
- Respiratory viral infections research
- Statistical Methods and Bayesian Inference
- Statistical Methods and Inference
- Sepsis Diagnosis and Treatment
- Pelvic floor disorders treatments
- Bayesian Methods and Mixture Models
- Intimate Partner and Family Violence
- Trauma and Emergency Care Studies
- Injury Epidemiology and Prevention
- Restraint-Related Deaths
- Data-Driven Disease Surveillance
- Anesthesia and Sedative Agents
- Pancreatic and Hepatic Oncology Research
- Silymarin and Mushroom Poisoning
- Liver Disease and Transplantation
- Opioid Use Disorder Treatment
- Biliary and Gastrointestinal Fistulas
University of Louisville
2016-2025
Lurie Children's Hospital
2019-2021
Springer Nature (Germany)
2010-2020
Weatherford College
2016
Universitätsklinikum des Saarlandes
2016
University Ucinf
2016
University of Louisville Hospital
2007-2015
Washington Poison Center
2009
Johannes Gutenberg University Mainz
2004-2008
Helios Dr. Horst Schmidt Kliniken Wiesbaden
2008
OBJECTIVE: Our objective was to conduct a pilot study identify discriminating bruising characteristics and model those findings into decision tool for screening children at high risk abuse. METHODS: A case-control of 0 48 months age who were admitted PICU because trauma performed. Case subjects (N = 42) victims physical abuse, control 53) accidental during the same time period. Bruising (total number body region) patient compared with abusive versus trauma. The development rule predicting...
<h3>Importance</h3> Bruising caused by physical abuse is the most common antecedent injury to be overlooked or misdiagnosed as nonabusive before an abuse-related fatality near-fatality in a young child. occurs from both nonabuse and abuse, but differences identified clinical decision rule may allow improved earlier recognition of abused <h3>Objective</h3> To refine validate previously derived bruising (BCDR), TEN-4 (bruising torso, ear, neck any on infant <4.99 months age), for...
OBJECTIVES The TEN-4-FACESp bruising clinical decision rule (BCDR) is a validated screening tool utilizing information about child’s body region bruised, age, and pattern of to predict abuse in children younger than 4 years age. Our objectives were (1) evaluate the accuracy BCDR predicting when only 1 bruise was present (2) identify other characteristics differentiating abusive from accidental injury young with single bruise. METHODS Patients included this secondary analysis those validation...
Objectives: Abusive head trauma is a leading cause of traumatic death and disability during infancy early childhood. Evidence-based screening tools for abusive do not exist. Our research objectives were 1) to measure the predictive relationships between isolated, discriminating, reliable clinical variables 2) derive reliable, sensitive, prediction rule that—if validated—can inform pediatric intensivists' decisions launch (or forego) an evaluation abuse. Design: Prospective, multicenter,...
Objective To evaluate the relationship and redundancy between gait speeds measured by 10 Meter Walk Test (10MWT) 6 Minute (6MWT) after motor incomplete spinal cord injury (iSCI). identify speed thresholds supporting functional ambulation as with Spinal Cord Injury Functional Ambulation Inventory (SCI-FAI). Design Prospective observational cohort. Setting Seven outpatient rehabilitation centers from Christopher Dana Reeve Foundation NeuroRecovery Network (NRN). Participants 249 NRN patients...
Lifetime occurrence of intimate partner violence (IPV) in women has been associated with increased prevalence aging-related chronic diseases, including those a pathophysiology involving inflammation. To begin to identify potential biologic mediators this relationship, cross-sectional study examined associations between past IPV and circulating levels C-reactive protein (CRP) interleukin-6 (IL-6)-measures linked emergence diseases-along vitro IL-6 production by peripheral blood mononuclear...
The authors evaluated trends between social, geographic, and demographic factors cases of select scheduled drugs (buprenorphine, fentanyl, hydrocodone, hydromorphone, morphine, methadone, oxycodone) using the Researched Abuse, Diversion Addiction-Related Surveillance System poison center data census data. Spontaneous calls from public healthcare professionals are recorded by centers a standardized, electronic collection system. We compared annual incidence total prescription opioid drug to...
Abstract Background Although community-acquired pneumonia (CAP) is one of the most common infections in children, no tools exist to risk stratify children with suspected CAP. We developed and validated a prediction model inform hospitalization decisions Methods performed prospective cohort study aged 3 months 18 years CAP pediatric emergency department. Primary outcome was disease severity, defined as mild (discharge home or for &lt;24 hours oxygen intravenous [IV] fluids), moderate...
BACKGROUND There is insufficient evidence to guide the initial evaluation of hypothermic infants. We aimed evaluate risk factors for serious bacterial infections (SBI) among infants presenting emergency department (ED). METHODS conducted a multicenter case-control study (rectal temperature &lt;36.5°C) ≤90 days ED who had blood culture collected. Our outcome was SBI (bacteremia, meningitis, and/or urinary tract infection). performed 1:2 matching. Historical, physical examination and...
The use of correlation coefficients in measuring the association between two continuous variables is common, but regular methods calculating correlations have not been extended to clustered data framework. For which observations within a cluster may be correlated, inferential procedures for marginal can biased. This particularly true number given informative being measured. In this paper, we apply principle inverse size reweighting develop estimators that remain valid framework when These...
Objective: We sought to determine the use and results of urine toxicology screens (UTS) in psychiatric patients undergoing a UTS test for medical clearance pediatric emergency department. Methods: A structured retrospective study was conducted over 6-month period. All department (ED) charts were reviewed 8 17 years who had UTS. Urine identified as medically indicated or routine-driven. Medically presented with seizures, syncope, headache, altered mental status, ingestion, chest...
Following a single oral administration of 140 mg Silymarin (Legalon® sugar-coated tablets) the components silybin and silychristin were determined in bile 9 cholecystectomized patients with T-drainage. Both isomers excreted form sulphate glucuronide conjugates. Silydianin, third component Silymarin, could not be detected an unchanged form.