A5022713744- Parasite Biology and Host Interactions
- Parasites and Host Interactions
- Parasitic infections in humans and animals
- Helminth infection and control
- Invertebrate Immune Response Mechanisms
- Aquaculture disease management and microbiota
- Bird parasitology and diseases
- Coccidia and coccidiosis research
- Zebrafish Biomedical Research Applications
- Numerical methods for differential equations
- Antimicrobial Peptides and Activities
- Fish Biology and Ecology Studies
- Identification and Quantification in Food
- Mathematical and Theoretical Epidemiology and Ecology Models
- Differential Equations and Numerical Methods
- Ion Transport and Channel Regulation
- Neuroinflammation and Neurodegeneration Mechanisms
- Electrolyte and hormonal disorders
- Marine Ecology and Invasive Species
University of Copenhagen
2014-2021
The anisakid nematodes Anisakis simplex (Rudolphi, 1809), Pseudoterranova decipiens (Krabbe, 1878) and Contracaecum osculatum 1802) occur as third-stage larvae in marine fish products may infect consumers ingesting raw or under-cooked products. Clinical symptoms associated with the infection, termed anisakidosis, vary from irritation of oesophagus stomach, via nausea, vomiting diarrhoea to severe epigastric abdominal pain. Third-stage A. are found body cavity, musculature various organs, P....
Abstract Populations of grey seals ( Halichoerus grypus ), sprats Sprattus sprattus ) and cod Gadus morhua in the Baltic Sea are relatively stationary. The present work, applying classical molecular helminthological techniques, documents that also share a common parasite, anisakid nematode Contracaecum osculatum , which uses as final host fish transport hosts. Sequencing mitochondrial genes COX1 COX2 adult worms from third-stage larvae livers (sprats cod), showed all gene variants occur both...
Abstract Ornamental fish, Xiphophorus maculatus, were imported from Singapore to Denmark for distribution local aquarists. Importers observed lethargic and erratic swimming patterns among fish forwarded a total of 30 pathological examination university diagnostic service. All diagnosed infected with encysted Centrocestus sp. metacercariae in gills (prevalence 100% mean intensity 454.5 ± 161.9 parasites per fish). Metacercariae identified by morphological molecular methods. Cysts (mean length...
Immersion-vaccines (bacterins) are routinely used for aquacultured rainbow trout to protect against Yersinia ruckeri (Yr). During immersion vaccination, take up and process the antigens, which induce protection. The zebrafish was as a model organism study uptake mechanisms subsequent antigen transport in fish. A genetically modified Yr developed constitutively express green fluorescent protein (GFP) bacterin production. Larval, juvenile adult transparent (tra:nac mutant) received bath 30...
Excretory/secretory (ES) compounds isolated from third-stage larvae of the anisakid nematode Contracaecum osculatum parasitizing liver Baltic cod were investigated for effects on immune gene expression in a zebrafish LPS-induced inflammation model. ES products containing series proteins, which some had enzymatic activity, injected solely or with LPS. proteins alone induced up-regulation number immune-related genes, but generally to lower degree compared When co-injected LPS, worm exacerbated...
The antimicrobial peptide CAP18 has been demonstrated to have a strong in vitro bactericidal effect on Yersinia ruckeri, but its activity vivo not described. In this work, we investigated whether protects rainbow trout Oncorhynchus mykiss (Walbaum) against enteric red mouth disease caused by pathogen either following i.p. injection or oral administration (in feed). It was found that of into juvenile before exposure Y. ruckeri associated with lowered mortality compared non-medicated fish...
Milk secretion involves significant flux of water, driven largely by synthesis lactose within the Golgi apparatus. It has not been determined whether this is simply a passive consequence osmotic potential between cytosol and Golgi, or it regulated flow. Aquaporins (AQPs) are membrane water channels that regulate flux. AQP1, AQP3 AQP5 have previously detected in mammary tissue, but evidence developmental regulation (altered expression according to physiological state gland) lacking their...
Abstract A parasitological investigation was performed on a total of 5380 Atlantic cod larvae, post-larvae and small juveniles sampled from the North Sea during period five years. The copepod Caligus elongatus (Von Nordmann, 1832) nematode Hysterothylacium aduncum (Rudolphi, 1802) were found at relatively high prevalence infection (4.6% 5.2%, respectively). by both parasites showed annual spatial variability. C. higher in 1992 compared to following years, whereas H. increased 2001.We...
Fish consumers may develop allergic reactions following the ingestion of fish products containing nematode larvae within genus Anisakis. Sensitized patients cross-react with proteins from insects, mites and mollusks, leading to even in absence offending food. Potential cross-reactivity Anisakis-allergic larval other zoonotic parasites present freshwater sea should be investigated due an increasing occurrence certain stocks, particularly Contracaecum osculatum. In this work, we evaluated...