- Aquaculture disease management and microbiota
- Parasite Biology and Host Interactions
- Aquaculture Nutrition and Growth
- Genetic and phenotypic traits in livestock
- Parasites and Host Interactions
- Myxozoan Parasites in Aquatic Species
- Fish Biology and Ecology Studies
- Viral Infections and Vectors
- Fish Ecology and Management Studies
- Helminth infection and control
- Environmental Toxicology and Ecotoxicology
- Heavy metals in environment
- Parasitic infections in humans and animals
- Gut microbiota and health
- Animal Virus Infections Studies
- Mercury impact and mitigation studies
- Advanced Materials and Mechanics
- Leptospirosis research and findings
- MicroRNA in disease regulation
- Microbial Metabolism and Applications
- Genetic diversity and population structure
- Microbial infections and disease research
- Allergic Rhinitis and Sensitization
- Cancer-related molecular mechanisms research
- Structural Analysis and Optimization
University of Copenhagen
2020-2024
University of Guilan
2018
Tarbiat Modares University
2014-2016
Fully developed teleosts possess a highly immune system comprising both innate and adaptive elements, but when hatching from the egg, yolksac larva is still at an ontogenetically incomplete stage with regard to physiological, including immunological, functions. The in these young fish stages far less compared youngs appearing reptile avian eggs most mammals parturition. In those vertebrate groups early ontogenetic development of fetus protected. lack fully larvae critical, because this...
Genetic selection of disease resistant fish is a major strategy to improve health, welfare and sustainability in aquaculture. Mapping single nucleotide polymorphisms (SNP) the genome may be fruitful tool define relevant quantitative trait loci (QTL) we here show its use for characterization Vibrio anguillarum rainbow trout ( Oncorhynchus mykiss ). Fingerlings were exposed pathogen V. serotype O1 solution 1.5 × 10 7 cfu/ml observed 14 days. Disease signs appeared 3 days post exposure (dpe)...
The parasitic ciliate Ichthyophthirius multifiliis has a low host specificity eliciting white spot disease (WSD) in wide range of freshwater fishes worldwide. parasite multiplies rapidly whereby the infection may reach problematic levels population within few days. targets both wild and cultured fish but huge economic impact protozoan is associated with mortality, morbidity treatment aquacultural enterprises. We have investigated potential for genetic selection WSD-resistant strains rainbow...
Abstract The protective effects of autogenous and commercial ERM immersion vaccines (bacterins based on Yersinia ruckeri, serotype O1, biotypes 1 2) for rainbow trout ( Oncorhynchus mykiss ) were compared in order to evaluate whether the use local pathogen strains immunization can improve protection. In addition, effect bacterin concentration was established product. Following sublethal challenge vaccinated non‐vaccinated control fish with live bacteria, we followed bacterial count (gills,...
Abstract Aeromonas salmonicid a subsp. salmonicida , the causative agent of furunculosis, has extensive negative effects on wild and farmed salmonids worldwide. Vaccination induces some protection under certain conditions but disease outbreaks occur even in vaccinated fish. Therefore, alternative control approaches are required to ensure sustainable expansion rainbow trout aquaculture. Selective breeding can be applied enhance host resistance pathogens. The present work used genome-wide...
Abstract Gill parasitic infections challenge farming of rainbow trout ( Oncorhynchus mykiss, Walbaum) in freshwater facilities. Apart from flagellates Ichthyobodo, (Pinto) and ciliates Ichthyophthirius (Fouquet) , Ambiphrya (Raabe), Apiosoma (Blanchard), Trichodinella (Sramek‐Husek) Trichodina (Ehrenberg)), we have shown that amoebae are prevalent Danish farms. Gills were isolated farmed six fish farms (conventional organic earth pond recirculated systems) placed on non‐nutrient agar (NNA)...
Single nucleotide polymorphisms (SNPs) on rainbow trout chromosomes Omy16 and Omy17 are associated with a lower parasitic load delayed-time-to-death following exposure to the ciliate Ichthyophthirius multifiliis causing white spot disease (WSD). We have evaluated application of two quantitative trait loci (QTL) represented by these SNPs for practical breeding purposes. Homozygous males served as parent fish securing offspring at least one allele (heterozygous homozygous fish) higher...
Flavobacterium psychrophilum is the causative agent of Bacterial Cold Water Disease (BCWD)/ Rainbow Trout Fry Syndrome (RTFS) in rainbow trout Oncorhynchus mykiss. The disease associated with significant mortality farms and thereby responsible for severe economical losses this part aquaculture industry. Vaccination very young life cycle stages not successful due to immature development adaptive immunity yolksac larvae early fry. This explains extensive usage antibiotics control BCWD/RTFS....
Abstract Vibriosis is a bacterial disease in fish caused by the Gram negative bacterium Vibrio anguillarum with severe impact on rainbow trout ( Oncorhynchus mykiss ) farming. Sustainable control methods should be developed and we here show that marker assisted selective breeding of naturally resistant to feasible. We have validated use single nucleotide polymorphism (SNP) SNP AX-89,945,921 (QTL chromosome 21). The QTL was previously found associated resistance vibriosis described following...
Pseudoterranoviasis is a zoonotic disease caused by nematode larvae of species within the genus Pseudoterranova (seal worm, cod worm). Most infections are gastrointestinal, oesophageal or pharyngeal, but here we report nasal infection. A 33-year-old patient suffering from rhinitis for 1.5 years recovered worm larva nose. Diagnosis was performed morphological and molecular characterization, showing causative agent to be third-stage decipiens (sensu stricto). Various infection routes discussed.
Eye flukes in fish are common freshwater lakes. Fish become infected by the penetration of cercariae released from snails, and high infection pressures may be associated with mortalities a Danish lake. Examination two other lakes, combined laboratory study, supported notion. We investigated 77 lakes level suggested occurrence cercarial pressure Dominant genera were Tylodelphys Diplostomum covering range species identified PCR sequencing 18S (partial)-ITS1-5.8S-ITS2-28S (partial) rDNA....
A parasitological investigation of Danish farmed freshwater (180 fish) and marine rainbow trout (170 fish), Oncorhynchus mykiss, was performed with an emphasis on the occurrence zoonotic parasites. Reliability methods applied assessed by examining fish from a stock wild Atlantic cod Gadus morhua caught in Sound (Øresund). While carried number parasites, we found that fish, both fresh environment, were free these Non-zoonotic parasites eye-flukes Diplostomum paracaudum, D. pseudospathaceum...
Caspian trout Salmo trutta caspius is an endangered subspecies of brown which native to the Sea. Restocking programmes have been established, but recent introduction rhabdovirus viral haemorrhagic septicaemia virus (VHSV) into Iranian rainbow farms connected waterbodies supporting wild may represent additional threat declining stock. The susceptibility and cultured populations this endemic was demonstrated by performing controlled VHSV infection experiments (both bath injection challenges)....
Marker-assisted selective breeding of fish with higher levels resistance towards specific pathogens may improve health, but the impact host genotype on susceptibility to multiple pathogen infections is still poorly investigated. This study examined in rainbow trout Oncorhynchus mykiss infection eye fluke Diplostomum pseudospathaceum. We used genetically selected trout, carrying SNPs associated parasitic ciliate Ichthyophthirius multifiliis, and exposed cercariae. showed that partly resistant...
Shell mechanisms are patterned surface-like structures with compliant deformation modes that allow them to change shape drastically. Examples include many origami and kirigami tessellations as well other periodic truss mechanisms. The deployment paths of a shell mechanism greatly constrained by the inextensibility constitutive material locally, compatibility requirements surface geometry globally. With notable exceptions (e.g., Miura-ori), often couples in-plane stretching out-of-plane...