A5100594470- Immunotherapy and Immune Responses
- Aquaculture disease management and microbiota
- T-cell and B-cell Immunology
- Immune Cell Function and Interaction
- Computational Drug Discovery Methods
- Plasmonic and Surface Plasmon Research
- Iron Metabolism and Disorders
- Metamaterials and Metasurfaces Applications
- Luminescence Properties of Advanced Materials
- Environmental Impact and Sustainability
- Data Management and Algorithms
- Orbital Angular Momentum in Optics
- Identification and Quantification in Food
- Energy, Environment, Economic Growth
- Antibiotic Resistance in Bacteria
- Sustainable Industrial Ecology
- Machine Learning in Bioinformatics
- Cancer-related molecular mechanisms research
- CRISPR and Genetic Engineering
- Digital Transformation in Industry
- Chaos control and synchronization
- Microwave Dielectric Ceramics Synthesis
- Pharmaceutical and Antibiotic Environmental Impacts
- Phytase and its Applications
- MicroRNA in disease regulation
Guangxi University
2023-2025
Shanghai Jiao Tong University
2023-2024
Qiqihar University
2024
Yan'an University
2024
Soochow University
2024
Second Affiliated Hospital of Soochow University
2024
Neijiang Normal University
2021-2024
Ruijin Hospital
2023-2024
Huazhong Agricultural University
2024
Shanghai Institute of Hematology
2023
We report the results of GUIDANCE-01 (NCT04025593), a randomized, phase II trial R-CHOP alone or combined with targeted agents (R-CHOP-X) guided by genetic subtyping newly diagnosed, intermediate-risk, high-risk diffuse large B cell lymphoma (DLBCL). A total 128 patients were randomized 1:1 to receive R-CHOP-X R-CHOP. The study achieved primary endpoint, showing significantly higher complete response rate than (88% vs. 66%, p = 0.003), overall 92% 73% (p 0.005). Two-year progression-free...
Abstract The protective effects of autogenous and commercial ERM immersion vaccines (bacterins based on Yersinia ruckeri, serotype O1, biotypes 1 2) for rainbow trout ( Oncorhynchus mykiss ) were compared in order to evaluate whether the use local pathogen strains immunization can improve protection. In addition, effect bacterin concentration was established product. Following sublethal challenge vaccinated non‐vaccinated control fish with live bacteria, we followed bacterial count (gills,...
HLA‐B*48:01:13 differs from HLA‐B*48:01:01:01 by one nucleotide in exon 5.
Metasurfaces have shown unprecedented capabilities in manipulating the phase, intensity, and polarization of electromagnetic waves. The coupling efficiency surface plasmon polaritons is overcome by sensitivity metasurfaces, but they face challenges application high-intensity-based SPPs confined to a metal. Based on spiral arrays combined with concentric groove, we experimentally demonstrate application-oriented polarization-controlled terahertz superfocusing emitting high-efficiency radially...
The Pseudomonas H6 lipopeptide is a surfactant which able to eliminate various parasitic pathogens including the ciliate Ichthyophthirius multifiliis in vitro. This suggests an application for aquaculture purposes. However, further information on efficacy of compound and possible immune modulation exposed fish should be gathered before usage at farm level considered. We performed vivo infection experiment using rainbow trout fry (mean weight 4.6 g, mean length 7.6 cm) as hosts I. theronts...
Antibiotic-resistant bacteria are emerging all the time, but continued emergence of novel resistance genes and genetic structures is even more alarming. Tigecycline currently important last barrier in treatment multidrug-resistant (MDR) infections. tet(X), a gene to tigecycline, most prevalent constantly variants. In this research, we characterized two MDR Acinetobacter indicus strains tigecycline that were identified analyzed by antimicrobial susceptibility testing, conjugation transfer,...
Copper homeostasis is associated with malignant biological behavior in various tumors. The excessive accumulation of copper can induce tumor death, which named cuproptosis, and it also closely related to progression the formation immune microenvironment. However, associations cuproptosis glioblastoma (GBM) prognosis microenvironment construction are poorly understood.First, TCGA GEO (GSE83300, GSE74187) merged datasets were used analyze association cuproptosis-related genes (CRGs) GBM. Then,...
Aquaculture, as a rapidly growing industry, plays significant role in global food production and economic development. However, various infectious diseases, particularly those caused by the gram-negative bacterium Aeromonas hydrophila, pose critical threat to sustainability productivity of world-wide aquaculture operations. Investigating molecular mechanisms A. hydrophila infection can help identify key targets for therapeutic interventions vaccines, thereby reducing losses associated with...
HLA‐A*30:01:24 differs from HLA‐A*30:01:01:01 by one nucleotide in exon 3.
As an integrated supply system combining multiple forms of energy, the regional multi-energy can realize functions mutual aid and efficient consumption renewable energy. It is expected to become important energy solution help achieve strategic goals carbon peaking neutrality. Existing distribution network analysis methods tools are difficult apply directly systems. This paper systematically combines digital twin technology with planning operation Based on core twins technologies such as...
Perennial ryegrass (Lolium perenne L.) is an agronomically important cool-season grass species that widely used as forage for ruminant animal production and cultivated in temperate regions the establishment of lawns. However, underlying genetic mechanism response L. to low temperature still unclear. In present study, we performed a comprehensive study identified 3,770 tandem duplication genes (TDGs) perenne, evolutionary analysis revealed might have undergone event approximately 7.69 Mya. GO...
The development of an innovative drug is complex and time-consuming, the target identification one critical steps in discovery process. Effective accurate targets can accelerate According to previous research, evolutionary genetic information genes has been found facilitate approved targets. In addition, allosteric proteins have great potential as due their structural diversity. However, this that could not collated existing databases. Here, we construct a comprehensive database named...
To overcome the lengthy timelines, high costs, and inefficiencies associated with traditional experimental approaches in predicting potential microbe-drug associations, we introduce a novel deep learning methodology, CapsTransNet-MDA, leveraging Capsule Networks (CapsuleNet) embedded multi-head attention Transformer mechanisms for relationships. Our approach begins by processing existing association matrix, followed combining computing feature matrices microbes drugs. These are then inputted...
This study utilizes data from listed companies on the Shanghai and Shenzhen stock exchanges 2010 to 2023 employs text analysis methods investigate impact of government environmental concerns corporate green technology innovation its underlying mechanisms. The empirical findings demonstrate that heightened significantly foster innovation. relationship remains robust across a series sensitivity analyses. mechanism reveals increased concern leads intensity regulation, drives intelligent...
Document databases are increasingly popular in various applications, but their queries challenging to write due the flexible and complex data model underlying document databases. This paper presents a synthesis technique that aims generate database from input-output examples automatically. A new domain-specific language is designed express representative set of an algebraic style. Furthermore, leverages novel abstraction collections for deduction efficiently prune search space quickly target...
Intracellular delivery of proteins has attracted significant interest in biological research and cancer treatment, yet it continues to face challenges due the lack effective approaches. Herein, we developed an efficient strategy via cationic α-helical polypeptide-mediated anionic proprotein delivery. The protein was reversibly modified with adenosine triphosphate dynamic covalent chemistry prepare (A-protein) abundant phosphate groups. A guanidyl-decorated polypeptide (LPP) employed not only...
A bandwidth-enhanced chaos synchronization communication system is proposed and its performance investigated numerically. The results show that, using a chaotic signal from driving vertical cavity surface-emitting laser (D-VCSEL) to drive two mutually coupled VCSELs (MC-VCSELs), the high-quality isochronal with over 30GHz bandwidth between corresponding LP modes in MCVCSELs can be obtained. Taking as different channels adopting masking (CMS) encryption scheme, this realize bidirectional...