A5100619636- Plant Stress Responses and Tolerance
- Turfgrass Adaptation and Management
- Plant biochemistry and biosynthesis
- Aeolian processes and effects
- Plant Molecular Biology Research
- Photosynthetic Processes and Mechanisms
- Plant and fungal interactions
- Plant Gene Expression Analysis
- Plant Growth Enhancement Techniques
- Molecular Biology Techniques and Applications
- Plant Physiology and Cultivation Studies
- Essential Oils and Antimicrobial Activity
- Seedling growth and survival studies
- Antibiotic Resistance in Bacteria
- Cancer therapeutics and mechanisms
- Bacterial biofilms and quorum sensing
- Endoplasmic Reticulum Stress and Disease
- Animal Genetics and Reproduction
- Microbial Metabolites in Food Biotechnology
- Wnt/β-catenin signaling in development and cancer
- Ubiquitin and proteasome pathways
- Monoclonal and Polyclonal Antibodies Research
- Animal Virus Infections Studies
- Phenothiazines and Benzothiazines Synthesis and Activities
- Traditional Chinese Medicine Studies
First Affiliated Hospital of Wannan Medical College
2006-2024
Heilongjiang University of Chinese Medicine
2024
BaiCheng Normal University
2024
First Hospital of Jilin University
2024
Jilin University
2013-2024
Guangxi Center for Disease Prevention and Control
2024
Guangxi University
2012-2024
State Key Laboratory For Conservation and Utilization of Subtropical Agro-Bioresources
2018-2024
Guangxi Veterinary Research Institute
2022-2024
Yunnan Agricultural University
2018-2023
Bacterial biofilms are widely associated with persistent infections. High resistance to conventional antibiotics and prevalent virulence makes eliminating these bacterial communities challenging therapeutic targets. We describe here the fabrication of a nanoparticle-stabilized capsule multicomponent core for treatment biofilms. The peppermint oil cinnamaldehyde combination that comprises capsules act as potent antimicrobial agents. An in situ reaction at oil/water interface between...
Identification of infectious bacteria responsible for biofilm-associated infections is challenging due to the complex and heterogeneous biofilm matrix. To address this issue minimize impact heterogeneity on identification, we developed a gold nanoparticle (AuNP)-based multichannel sensor detect identify biofilms based their physicochemical properties. Our results showed that can discriminate six bacterial including two composed uropathogenic bacteria. The capability was further demonstrated...
Perennial ryegrass (Lolium perenne) is an important forage grass with high yield and superior quality in temperate regions which widely used parks, sport field other places. However, perennial moderately tolerant to salinity stress compared commercial cultivars salt reduces their growth productivity. Aspergillus aculeatus has been documented participate alleviating damage induced by salinity. Therefore, the objective of this study was investigate mechanisms underlying A. aculeatus-mediated...
Erigeron breviscapus, a traditional Chinese medicinal plant, is enriched in flavonoids that are beneficial to human health. While we know R2R3-MYB transcription factors (TFs) crucial flavonoid pathway, the transcriptional regulation of biosynthesis E. breviscapus has not been fully elucidated. Here, EbMYBP1, factor, was uncovered as regulator involved accumulation. Transcriptome and metabolome analysis revealed large group genes related were significantly changed, accompanied by increased...
Erigeron breviscapus is a Compositae plant, and its rich flavonoids have shown strong preventative curative effects in the treatment of cardio- cerebrovascular diseases. bHLH genes play crucial role plant growth development. There are 116 EbbHLH E. breviscapus, each gene has been named based on chromosome location. Our phylogenetic analysis divided these into 18 subfamilies. To further investigate function, EbbHLH80 was isolated from leaves. Next, transcriptomic metabolomic analyses tobacco...
Cynanchum komarovii Al Iljinski is a xerophytic plant species widely distributing in the severely adverse environment of deserts northwest China. At present, detailed transcriptomic and genomic data for C. are still insufficient public databases. To investigate changes drought-responsive genes explore mechanisms drought tolerance komarovii, approximately 27.5 GB sequencing were obtained using Illumina technology. After de novo assembly 148,715 unigenes generated with an average length 604...
A series of novel 8-OMe ciprofloxacin (CPFX)-hydrazone/azole hybrids were designed, synthesized, and evaluated for their in vitro biological activities. Our results reveal that all the hydrozone-containing (except 7) show potency against Mycobacterium tuberculosis (MTB) H37Rv (minimum inhibitory concentration (MIC): <0.5 μM), which is better than parent drug CPFX, comparable to moxifloxacin isoniazid, some tested Gram-positive strains (MIC: 0.06-4 μg/mL), most Gram-negative ≤0.03-4 μg/mL).
Abstract Background Despite its good salt-tolerance level, key genes and pathways involved with temporal salt response of common bermudagrass ( Cynodon dactylon (L.) Pers.) have not been explored. Therefore, in this study, to understand the underlying regulatory mechanism following different period exposure, a comprehensive transcriptome analysis roots was conducted. Results The transcripts regulated after 1 h, 6 or 24 h hydroponic exposure 200 mM NaCl were investigated. Dataset series...
BackgroundBiofilm formation is a major factor in the resistance mechanism of Klebsiella pneumoniae. This study aimed to evaluate effects sodium hypochlorite on biofilm K. pneumoniae with different drug resistance.MethodsWe collected 3 types respectively. The growth trend biofilms drug-resistant was quantified by measuring OD590 for 7 consecutive days using crystal violet staining. Scanning confocal fluorescence microscopy used observe morphology.ResultsAfter adding hypochlorite, there were...
bHLH transcription factors are involved in multiple aspects of plant biology, such as the response to abiotic stress. Erigeron breviscapus is a composite plant, and its rich flavonoids have strong preventive therapeutic effects on cardio cerebral vascular disease. EbbHLH80, gene from E. that positively regulates flavonoid synthesis, was previously characterized. However, it unclear whether EbbHLH80 increases accumulation, which affects salt tolerance. The function transgenic tobacco seeds...
Wnt signaling has emerged as a major regulator of tissue development by governing the self-renewal and maintenance stem cells in most types. As key upstream pathway, transmembrane E3 ligase ZNRF3 recently been established to play role negative regulation targeting Frizzled (FZD) receptor for ubiquitination degradation. However, ZNRF3, particular turnover is still unclear. Here we report that accumulated presence proteasome inhibitor treatment independent its E3-ubiquitin activity....
Well diffusion method was used to evaluate the antibacterial activity of Eucalyptus camaldulensis, while antifungal effect assessed by calculating reduction percent in radial growth mycelia. The inhibition zones exerted E. camaldulensis crude extracts varied significantly (p ≤ 0.01). capsule extract (acetone 30%) highly inhibited Acinetobacter baumannii (35 mm clear zone). highest against Rhizopus stolonifer with a its reached 96%. bacterial MICs ranged from 20 0.5 mg/mL Escherichia coli and...
Background: Protein kinase R (PKR)-like endoplasmic reticulum (PERK) is a type I transmembrane protein that functions as an (ER) stress sensor to regulate global synthesis. Recent research studies suggest PERK, important receptor of unfolded response, involved in the pathogenesis many cancers. This study aimed investigate PERK expression and its relationship with prognosis pan-cancer attempted explore relevant mechanism regulation cancer pathogenesis. Methods: The Oncomine TIMER databases...
Nucleosome assembly protein 1-like 1 (NAP1L1) is significantly involved in the development of various cancers. However, its role molecular mechanism nasopharyngeal carcinoma (NPC) remains undetermined. In this study, we detected upregulated expression NAP1L1 mRNA and levels by quantitative polymerase chain reaction Western blot analysis NPC cell lines. Results immunohistochemistry tissue biopsies showed that promoted progression negatively correlated with poor prognosis patients. Suppression...