Nana Liu

ORCID: 0000-0001-9745-8525
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About
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Research Areas
  • Plant-Microbe Interactions and Immunity
  • Metal-Organic Frameworks: Synthesis and Applications
  • Photosynthetic Processes and Mechanisms
  • Plant tissue culture and regeneration
  • Plant Reproductive Biology
  • Plant Gene Expression Analysis
  • Plant Stress Responses and Tolerance
  • Plant Molecular Biology Research
  • Polysaccharides and Plant Cell Walls
  • CRISPR and Genetic Engineering
  • RNA Research and Splicing
  • Chemical Synthesis and Reactions
  • Plant Taxonomy and Phylogenetics
  • Virus-based gene therapy research
  • Plant nutrient uptake and metabolism
  • Advanced Cellulose Research Studies
  • Advanced Nanomaterials in Catalysis
  • Plant pathogens and resistance mechanisms
  • Soil Carbon and Nitrogen Dynamics
  • Plant biochemistry and biosynthesis
  • Polyoxometalates: Synthesis and Applications
  • Cytomegalovirus and herpesvirus research
  • 14-3-3 protein interactions
  • Plant Surface Properties and Treatments
  • Gut microbiota and health

Liaocheng University
2017-2025

Cell Technology (China)
2017-2025

Qingdao Agricultural University
2021-2025

University of Jinan
2023-2025

Tianjin Medical University General Hospital
2025

Ministry of Agriculture and Rural Affairs
2023-2024

Huawei Technologies (China)
2024

National Clinical Research
2023

Yangzhou University
2023

South China Normal University
2023

Pectins are major components of the primary plant cell wall, which functions as barrier against pathogens. Pectin methylesterases (PMEs) catalyze demethylesterification homogalacturonan domains pectin in wall. Their activity is regulated by PME inhibitors (PMEIs). Here, we provide evidence that methylesterase-inhibiting protein GhPMEI3 from cotton (Gossypium hirsutum) responses to infection fungus Verticillium dahliae. interacts with PMEs and regulates expression a specific fungal...

10.1104/pp.17.01399 article EN PLANT PHYSIOLOGY 2018-01-23

Current DNA base editors contain nuclease and deaminase that enables deamination of cytosine (C) or adenine (A), but no method for guanine (G) thymine (T) editing is available at present. Here we developed a deaminase-free glycosylase-based editor (gGBE) with G ability, by fusing Cas9 nickase engineered N-methylpurine glycosylase protein (MPG). By several rounds MPG mutagenesis via unbiased rational screening using an intron-split EGFP reporter, demonstrated gGBE could increase efficiency...

10.1093/nsr/nwad143 article EN cc-by National Science Review 2023-05-16

Salicylic acid (SA) is an important plant hormone and signal required for establishing resistance to diverse pathogens diseases. The abundant polyphenols in tea plants also defend from biotic abiotic stresses. However, whether exogenous SA would increase the of adversity relationship between are still poorly understood. Here, we carried out treatment on seedlings performed transcriptome sequencing. inhibited phenylpropanoid flavonoid metabolic pathways but promoted lignin pathways. increased...

10.1021/acs.jafc.2c07046 article EN Journal of Agricultural and Food Chemistry 2023-01-25

DNA base editors enable direct editing of adenine (A), cytosine (C), or guanine (G), but there is no editor for thymine (T) currently. Here we develop two deaminase-free glycosylase-based T (gTBE) and C (gCBE) by fusing Cas9 nickase (nCas9) with engineered human uracil glycosylase (UNG) variants. By several rounds structure-informed rational mutagenesis on UNG in cultured cells, obtain gTBE gCBE high activity T-to-S (i.e., T-to-C T-to-G) C-to-G conversions, respectively. Furthermore, conduct...

10.1038/s41467-024-49343-5 article EN cc-by Nature Communications 2024-06-08

Abstract Polygalacturonase-inhibiting protein (PGIP), belonging to a group of plant defence proteins, specifically inhibits endopolygalacturonases secreted by pathogens. Herein, we showed that purified GhPGIP1 is functional inhibitor Verticillium dahliae and Fusarium oxysporum f. sp. vasinfectum , the two fungal pathogens causing cotton wilt. Transcription was increased in upon infection, wounding, treatment with hormone H 2 O . Resistance examined its virus-induced gene silencing...

10.1038/srep39840 article EN cc-by Scientific Reports 2017-01-12

Germin-like proteins (GLPs) are water-soluble plant glycoproteins belonging to the cupin superfamily. The important role of GLPs in responses against various abiotic and biotic stresses, especially pathogens, is well validated. However, little known about cotton relation fungal pathogens. Here, a novel GLP gene was isolated from Gossypium hirsutum designated as GhABP19. expression GhABP19 upregulated plants inoculated with Verticillium dahliae Fusarium oxysporum response treatment jasmonic...

10.3389/fpls.2019.00583 article EN cc-by Frontiers in Plant Science 2019-05-08

It is necessary to find more simple methods improve the detection selectivity and sensitivity of antibiotics. Herein, we constructed a novel three-dimensional (3D) Cd-MOF LCU-117 assembled from p-terphenyl-4,2″,5″,4'-tetracarboxylic acid, which showed special 3D helical structure with carboxylic acid ligands nitrogen-containing crossing each other vertically. Luminescence measurements indicated that has high toward Eu3+ through ratiometric effect. Meanwhile, this complex itself could detect...

10.1021/acs.inorgchem.2c04246 article EN Inorganic Chemistry 2023-02-14

Two supramolecular Co-MOF isomers, namely, {[Co(L)0.5(m-bimb)]·3H2O}n (LCU-115) and {[Co(L)0.5(p-bimb)]·3H2O}n (LCU-116), were synthesized from an amide-containing carboxylic acid N,N″-(3,5-dicarboxylphenyl)benzene-1,4-dicarboxamide (H4L) two flexible positional isostructural N-containing ligands m-bimb p-bimb (m-bimb = 1,3-bis((1H-imidazol-1-yl)methyl)benzene; 1,4-bis((1H-imidazol-1-yl)methyl)benzene). The carboxylate connect Co(II) centers to form 2D metal-carboxylate sheets, which are...

10.1021/acs.inorgchem.2c03719 article EN Inorganic Chemistry 2023-01-26

Two Co(II) metal-organic frameworks (Co-MOFs), namely, [Co(DMTDC)(bimb)]

10.1021/acs.inorgchem.4c02497 article EN Inorganic Chemistry 2024-10-02

Peach (Prunus persica cv. Dajiubao) was chosen as a model to clarify the roles of IAA and ABA during fruit ripening process. Seventy days after flowering (DAF), fruits were treated with (0.1 mmol·L−1 1 mmol·L−1, respectively) transporter inhibitor (NPA) biosynthesis (NDGA). decreased concentration, increased ethylene leading (70 DAF) softening coloration. NPA had opposite effect. concentrations, hardness lack color. NDGA similar effects application. A qPCR analysis indicated that in immature...

10.1016/j.hpj.2019.01.005 article EN cc-by-nc-nd Horticultural Plant Journal 2019-02-05

The pathogenesis of inflammatory bowel disease may be related to local damage and disturbances in intestinal microecology. Probiotic therapy is a safe effective therapeutic approach. Considering that fermented milk accepted enjoyed by many people as daily dietary intervention strategy, its potential alleviate dextran sulfate sodium (DSS)-induced chronic colitis mice needs explored. In this study, we evaluated the effects Lactiplantibacillus plantarum ZJ316-fermented establishing mouse model...

10.3168/jds.2023-23251 article EN cc-by Journal of Dairy Science 2023-05-18

Cynanchum komarovii Al Iljinski is a xerophytic plant species widely distributing in the severely adverse environment of deserts northwest China. At present, detailed transcriptomic and genomic data for C. are still insufficient public databases. To investigate changes drought-responsive genes explore mechanisms drought tolerance komarovii, approximately 27.5 GB sequencing were obtained using Illumina technology. After de novo assembly 148,715 unigenes generated with an average length 604...

10.1186/s12864-015-1873-x article EN cc-by BMC Genomics 2015-10-06

Plant cellulose is synthesized by rosette-structured synthase (CESA) complexes (CSCs). Each CSC composed of multiple subunits CESAs representing three different isoforms. Individual CESA proteins contain conserved catalytic domains for catalyzing synthesis, other such as plant-conserved sequences, and class-specific regions that are thought to facilitate complex assembly trafficking. Because the current lack atomic-resolution structures plant CSCs or CESAs, molecular mechanism through which...

10.1105/tpc.20.00202 article EN cc-by The Plant Cell 2020-04-23

A photoredox-catalyzed three-component radical cascade reaction of β,γ-unsaturated oximes/hydrazones, the sulfur dioxide surrogate DABCO·(SO 2 ) and alkenes under mild conditions is developed.

10.1039/d1qo00957e article EN Organic Chemistry Frontiers 2021-01-01

Two new isomorphic metal–organic frameworks (MOFs) have been developed as multifunctional materials for carbon dioxide fixation and fluorescence detection.

10.1039/d3dt03466f article EN Dalton Transactions 2023-12-28

Abstract Benzoates, particularly salicylic acid (SA) and its derivatives, play critical roles in plant immune responses basal defense through hydroxylation glycosylation. Anthracnose is one of the most common devastating diseases tea plants (Camellia sinensis). However, role SA derivatives immunity resistance to anthracnose remains largely unexplored. In present study, we identified characterized a glycosyltransferase, CsUGT74B5, which was significantly downregulated seedlings upon...

10.1093/hr/uhaf009 article EN cc-by Horticulture Research 2025-01-14

Sustainable conversion of epoxides and propargylic amines using CO2 could produce valuable chemical products. Efficient generally requires harsh conditions such as noble-metal catalysts, cocatalysts, toxic solvents, thereby underscoring the crucial need for environmentally friendly non-noble-metal metal–organic framework (MOF) catalysts. In this study, we designed a novel zinc-based with 5-fold interpenetrating diamond framework, specifically {[Zn(DMTDC)(bpy)]·H2O}n (Zn-MOF-2), where H2DMTDC...

10.1021/acs.inorgchem.4c05485 article EN Inorganic Chemistry 2025-02-26

Polymer dispersed liquid crystals (PDLC), as an electrochromic material, can rapidly undergo reversible switching between scattering and transparent states, demonstrating significant potential in electro-optic fields. However, traditional PDLC films are...

10.1039/d5tc00283d article EN Journal of Materials Chemistry C 2025-01-01
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