- Renal Transplantation Outcomes and Treatments
- Organ Transplantation Techniques and Outcomes
- Organ Donation and Transplantation
- Blood transfusion and management
- Power Line Communications and Noise
- Topic Modeling
- Robotics and Sensor-Based Localization
- IoT Networks and Protocols
- Digital Innovation in Industries
- Trauma, Hemostasis, Coagulopathy, Resuscitation
- Endoplasmic Reticulum Stress and Disease
- Venous Thromboembolism Diagnosis and Management
- E-commerce and Technology Innovations
- Blood properties and coagulation
- Bacteriophages and microbial interactions
- Bacillus and Francisella bacterial research
- Methane Hydrates and Related Phenomena
- Industrial Technology and Control Systems
- Telecommunications and Broadcasting Technologies
- Polymer-Based Agricultural Enhancements
- Control and Dynamics of Mobile Robots
- Extracellular vesicles in disease
- Video Surveillance and Tracking Methods
- Advanced MIMO Systems Optimization
- Advanced Measurement and Detection Methods
Zhejiang A & F University
2025
West China Hospital of Sichuan University
2020-2024
Sichuan University
2020-2024
Ruian People's Hospital
2024
Cornell University
2016-2024
Wenzhou Medical University
2023-2024
Heilongjiang Bayi Agricultural University
2024
Weill Cornell Medicine
2022-2024
Chongqing University of Science and Technology
2022-2024
Tongji Hospital
2016-2023
Abstract Age-related macular degeneration (AMD) is the leading cause of blindness among elderly. Dry AMD has unclear etiology and no treatment. Lipid-rich drusen are hallmark dry AMD. An mouse model insights into drusenogenesis keys to better understanding this disease. Chloride intracellular channel 4 (CLIC4) a pleomorphic protein regulating diverse biological functions. Here we show that retinal pigment epithelium (RPE)-specific Clic4 knockout mice exhibit full spectrum functional...
Abstract Organic electrode materials have attracted tremendous attention for potassium‐ion batteries (PIBs). Whereas, high‐performance anodes are scarcely reported. Herein, a novel hexaazatriphenylene potassium carboxylate (HAT‐COOK) is proposed as anode PIBs. The rich CN/CO bonds guarantee the high theoretical capacity. It also demonstrated HAT‐COOK more compatible with water‐soluble binders than hydrophobic fluoride binders, forming homogenous film, maintaining structural integrity, and...
Abstract Hepatocyte-specific HMGB1 deletion has been found to worsen the injury and inflammation in liver ischemia-reperfusion (IRI), highlighting a role for intracellular cellular protection. Down-regulation of nuclear by small interfering RNA (siRNA) might not only decrease its injurious extracellular reducing release but also serve maintain beneficial role, thus protecting against IRI. We established non-lethal IRI model mice via segmental hepatic warm ischemia 1 h reperfusion 6 h....
Resource-limited settings present unique engineering challenges for medical diagnostics. Diagnosis is often needed those unable to reach central healthcare systems, making portability and independence from traditional energy infrastructure essential device parameters. In 2014, our group presented a microfluidic that performed solar-powered variant of the polymerase chain reaction, which we called solar thermal PCR. this work, expand on previous effort by presenting an integrated, portable,...
Abstract Vacuolar protein sorting 35 (VPS35), the core component of retromer complex which regulates endosomal trafficking, is genetically linked with Parkinson’s disease (PD). Impaired vision a common non-motor manifestation PD. Here, we show mouse retinas VPS35-deficient rods exhibit synapse loss and visual deficit, followed by progressive degeneration concomitant emergence Lewy body-like inclusions phospho-α-synuclein (P-αSyn) aggregation. Ultrastructural analyses reveal accumulate...
The source apportionment of pollutants is the key to preventing and controlling pollution caused by heavy metals in soils. aim this study was investigate main sources soils black shale areas western Zhejiang, China. Based on geostatistical spatial analysis, research employed positive matrix factorization (PMF) for paddy soil. results showed that contaminated arable were concentrated southern areas. At least five major screened study: natural (39.66%), traffic emissions (32.85%), industrial...
It has been reported that kidney retransplant patients had high rates of early acute rejection due to previous sensitization. In addition the antibody-mediated (ABMR) received widespread attention, T-cell-mediated (TCMR) may be another important issue in renal retransplantation. current single-center retrospective study, we included 33 and 90 first transplant with similar protocols induction maintenance therapy. Analysis focused particularly on incidence patterns episodes, as well one-year...
Dynamic obstacle avoidance is crucial in autonomous driving, ensuring vehicle safety by preventing collisions and enhancing driving efficiency. algorithms have made significant progress due to deep learning. However, video-based target detection methods can suffer from missed or false detections when processing consecutive frames, especially for high-speed moving targets complex dynamic scenes. Multi-target tracking require intricate algorithm designs initialization occluded object recovery,...
Using pediatric donors for single-kidney transplantation (SKT) can increase the number of possible recipients. However, it is unclear when SKT involving small and adult recipients safely be performed without compromising graft outcome.From 2013 to 2017, a total 102 SKTs in were our center using aged <12 years. We compared outcomes from 8 36 months (the small-kidney group [SKG], n = 46) 3 12 years big-kidney [BKG], 56). The median follow-up time was 30 SKG 28 BKG.All patients achieved...
Concanavalin A (Con A) is known to be a T-cell mitogen and has been shown induce hepatitis in mice through the triggering of conventional T cells NKT cells. However, it remains unknown whether Con itself can directly rapid hepatocyte death absence functional immune system. Here, by using an immunodeficient mouse model, we found rapidly induced liver injury vivo despite lack immunocyte involvement. We further observed vitro that hepatocytes underwent dose-dependent but caspase-independent...
Cysteiniphilum is a newly discovered genus in 2017 and phylogenetically closely related to highly pathogenic Francisella tularensis. Recently, it has become an emerging pathogen humans. However, the complete genome sequence of lacking, genomic characteristics genetic diversity, evolutionary dynamics, pathogenicity have not been characterized. In this study, first reported clinical isolate QT6929 was sequenced, comparative genomics analyses were conducted unveil landscape diversity...
Aims: Carbon monoxide (CO) confers antiproliferative effects on T cells; however, how these are produced remains unclear. Reactive oxygen species (ROS) have recently emerged as important modulators of cell proliferation. In this study, we aimed to determine whether the inhibitory CO proliferation dependent inhibition ROS signaling. Results: Pretreatment with CO-releasing molecule-2 (CORM-2) had potent mouse stimulated by anti-CD3/CD28 antibodies. Interestingly, CORM-2 pretreatment markedly...
Entity matching (EM) is the most critical step for entity resolution (ER). While current deep learningbased methods achieve very impressive performance on standard EM benchmarks, their realworld application much frustrating. In this paper, we highlight that such gap between reality and ideality stems from unreasonable benchmark construction process, which inconsistent with nature of therefore leads to biased evaluations approaches. To end, build a new corpus re-construct benchmarks challenge...
Background. Angina is a hallmark symptom of cardiovascular disease, which has become an important public health issue in Taiwan. The purpose this study was to examine the prevalence angina and its risk factors elderly Taiwanese.
Abstract Background Both the complement and coagulation systems play important roles in development of hyperacute or acute antibody‐mediated xenograft rejection. Atrase B is a novel metalloproteinase isolated from venom Naja atra . In this study, we investigated inhibitory effects atrase on activation coagulation, as well effect survival discordant xenotransplantation model. Methods The vitro anti‐complement activity was evaluated using normal human serum (NHS)‐mediated complement‐dependent...
Micro and sub-micro-spherical copper powder slurries were elaborately prepared to fabricate different types of porous coating surfaces. These surfaces further treated with low surface energy modification obtain the superhydrophobic slippery capacity. The wettability chemical component measured. results showed that both micro sub-micro layer greatly increased water-repellence capability substrate compared bare plate. Notably, PFDTES-fluorinated yielded ability against water under 0 °C a...