A5039902413- Cardiovascular Function and Risk Factors
- Pulmonary Hypertension Research and Treatments
- Cardiac Valve Diseases and Treatments
- Cardiovascular and exercise physiology
- Congenital Heart Disease Studies
- Coronary Artery Anomalies
- Cardiac Imaging and Diagnostics
- Coronary Interventions and Diagnostics
- Cardiac Health and Mental Health
- Heart Rate Variability and Autonomic Control
- Vascular anomalies and interventions
- Acute Myocardial Infarction Research
- Cardiac Arrhythmias and Treatments
- Atrial Fibrillation Management and Outcomes
- Venous Thromboembolism Diagnosis and Management
- Cardiac Structural Anomalies and Repair
- Antiplatelet Therapy and Cardiovascular Diseases
- Central Venous Catheters and Hemodialysis
- Pericarditis and Cardiac Tamponade
- Chronic Obstructive Pulmonary Disease (COPD) Research
- Cerebrovascular and Carotid Artery Diseases
- Cardiovascular Health and Disease Prevention
- Infective Endocarditis Diagnosis and Management
- Pharmaceutical Practices and Patient Outcomes
- Cardiac electrophysiology and arrhythmias
Manipal Academy of Higher Education
2016-2025
Kasturba Medical College, Manipal
2016-2025
Babu Banarasi Das University
2023
St. John's National Academy of Health Sciences
2023
Arena Pharmaceuticals (United States)
2021
Springhouse
2021
Janssen (United States)
2018-2021
Sify Technologies (India)
2021
Mahatma Gandhi Mission Medical College and Hospital
2021
Princess Alexandra Hospital
2020
Drug-drug interactions (DDIs) are defined astwo ormoredrugs interacting in such a mannerthatthe effectiveness ortoxicity of one or more drugs is altered. DDI patients receiving multidrug therapy major concern. The aim the present study was to assess incidence and riskfactors DDIs admitted cardiology unit teaching hospital. A prospective, observational carried outfora period 3 months (April-July 2009). During period, total 600 prescriptions were analyzed it found that 88 had at least DDI....
The geometry of carotid bifurcation is a crucial contributing factor to the localization atherosclerotic lesions. Currently, studies on are limited region near bifurcation. This study aimed determine influence blood flow using numerical simulations considering magnitude haemodynamic parameters in extended regions artery. In present study, analysis carried out non-Newtonian viscosity model for patient-specific geometries consisting both Left and Right arteries. A 3D geometric generated...
Effective myocardial reperfusion in ST-Elevation Myocardial Infarction (STEMI) remains challenging despite advancements primary percutaneous coronary intervention (PCI). This study evaluates the impact of thrombus aspiration (TA) and saline autotransfusion (SAT) compared to standard PCI (NOTA) on flow dynamics perfusion. prospective cohort enrolled 157 STEMI patients who underwent PCI. Participants were divided into two groups: TA+SAT (n = 80) NOTA 77). Clinical parameters such as blood...
Abstract Acute pulmonary thromboembolism (PTE) can range from asymptomatic cases to severe presentations with cardiogenic shock. We report a 67-year-old male diabetes and hypertension, presenting progressive dyspnea hemodynamic instability. Clinical examination revealed sinus tachycardia, right ventricular dysfunction on echocardiography, elevated biomarkers indicative of PTE. Chest X-ray showed classic signs including Westermark's, Palla's, Fleischner's Chang's signs, raising suspicion for...
Abstract Aims Women are under-represented in cardiac rehabilitation (CR), especially lower-income settings. This study tested Technology-bAsed Cardiac Therapy (TaCT) on functional capacity, risk factors, quality of life (QoL; MacNew), heart-health behaviours (e.g. Global Physical Activity Questionnaire), symptoms angina), and morbidity hospitalization procedure) women. Methods results Single-centre, single-blind, two parallel arms (1:1 SNOSE) randomized superiority trial, undertaken an...
Aims: To determine the effects of combined in-patient rehabilitation with a home-based program on function and quality life. Setting Design: Tertiary care, university teaching hospital, randomized controlled trial. Patients Methods: Thirty admitted patients congestive heart failure New York Heart Association class II -IV. A five step individualised phase-1 cardiac followed by structured home based for eight weeks was given to experimental group while control only received physician directed...
The objective of this study was to assess the effects home-based exercise training (HBET) on function and quality life (QoL) in patients with pulmonary hypertension (PH). A prospective, nonblinded, randomized clinical trial carried out 84 medically stable PH belonging any functional class or etiology either sex. Patients were standard care HBET. Both groups also received education using Pulmonary Hypertension Manual (PulHMan). Outcomes included capacity from 6-min walk distance (6MWD), QoL...
Objectives To evaluate, in the FLEX Registry, clinical outcomes of an ultrathin (60 µm) biodegradable polymer-coated Supraflex sirolimus-eluting stent (SES) for treatment coronary artery disease. Additionally, to determine vascular response SES through optical coherence tomography (OCT) analysis. Setting Multicentre, single-arm, all-comers, observational registry patients who were treated with SES, between July 2013 and May 2014, at nine different centres India. Participants 995 (1242...
Background: Exercise training as a part of cardiac rehabilitation aims to restore patient with heart disease health. However, left ventricular ejection fraction (LVEF) is clinically used predictor long-term prognosis in coronary artery (CAD) patients, there scarcity data on the effectiveness exercise-based LVEF. Objective: To investigate LVEF early post-event CAD patients. Patients and Methods: In single blinded, randomized controlled trial, post-coronary event patients from age group 35-75...
Venous aneurysms arising from the mediastinal systemic veins are rare. There only 27 reported cases of such aneurysms. Majority arise superior vena cava. We reporting a saccular aneurysm cava in 58-year-old male. The chest radiogram suggested mass and computed tomogram was suggestive aortic arch aneurysm. Aortography venography confirmed diagnosis as A 7 cm distal half resected through median sternotomy. surgery done to prevent pulmonary thrombo-embolism.
Lithium is a commonly used drug in psychiatric practice. It the treatment of depression and bipolar disorder. has narrow therapeutic index with documented adverse effects even near levels. myriad manifestations at toxic The cardiovascular range from relatively benign ST-T wave changes to fatal arrhythmias. We describe case lithium toxicity which presented as junctional rhythm later showed variety such complete heart block, atrial fibrillation, sinus bradycardia, finally reverted par serum
Central venous stenosis is an important hindrance to long-term maintenance of arteriovenous access in the upper extremities dialysis patients.The present study was done determine feasibility and clinical success endovascular approach for treatment symptomatic central associated with significant ipsilateral limb edema patients vascular limb.A database hemodialysis who underwent from January 2014 2017 at our institute retrospectively reviewed. Follow-up variable.The included ten (6 men 4...
Background. Sleep-disordered breathing (SDB) is a common yet largely underdiagnosed entity in developing countries. It one treatable condition that known to adversely affect the mortality and morbidity heart failure (HF). This study of first attempts aimed at studying SDB chronic HF patients from an Indian subcontinent. Objectives. The aim this was prevalence, type, characteristics their association with severity left ventricular (LV) systolic function also determine relevance symptoms...
There is sparse Indian data on whether fetal echocardiography among pregnant diabetics would be useful to predict adverse perinatal/neonatal outcome.To study cardiac changes in diabetic mothers and non-diabetic controls from 24 weeks gestation until the neonatal period; correlate them with maternal glycemic control; their implications outcome.Prospective observational cohort study. Pregnant (17 overt, 66 gestational) recruited beyond weeks, divided as well (39) poorly (44) controlled, based...
Exercise training in pulmonary arterial hypertension (PAH) has been gaining popularity with guidelines now recommending it as an important adjunct to medical therapy. Despite improvements function and quality of life, understanding metabolic changes their mechanisms remain unexplored. The objective this study was therefore understand the basis exercise a monocrotaline model PAH. 24 male Wistar rats (age: 8–12 weeks mean body weight: [262.16 ± 24.49] gms) were assigned one four groups (i.e.,...
Coronary sinus (CS) anomalies, although infrequent, are increasingly diagnosed with advances in interventional procedures and imaging techniques. Most cases asymptomatic incidentally diagnosed. We present a case of an elderly male without comorbidities who presented acute angina. catheterisation revealed double-vessel disease, but incidentally, sequential angiograms captured contrast filling the levophase CS, revealing giant CS. Primary percutaneous angioplasty right coronary artery was...