Ruth Gottstein

ORCID: 0000-0001-8125-0850
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About
Contact & Profiles
Research Areas
  • Hemoglobinopathies and Related Disorders
  • Neonatal Respiratory Health Research
  • Blood groups and transfusion
  • Blood transfusion and management
  • Neonatal Health and Biochemistry
  • Airway Management and Intubation Techniques
  • Erythrocyte Function and Pathophysiology
  • Respiratory Support and Mechanisms
  • Infant Development and Preterm Care
  • Antibiotics Pharmacokinetics and Efficacy
  • Autopsy Techniques and Outcomes
  • Cerebrospinal fluid and hydrocephalus
  • Interprofessional Education and Collaboration
  • Phonocardiography and Auscultation Techniques
  • Blood disorders and treatments
  • Traumatic Brain Injury and Neurovascular Disturbances
  • Nursing Roles and Practices
  • Obstructive Sleep Apnea Research
  • Ethics and Legal Issues in Pediatric Healthcare
  • Wireless Body Area Networks
  • Neuroscience of respiration and sleep
  • Neonatal and fetal brain pathology
  • Child and Adolescent Health
  • COVID-19 Impact on Reproduction
  • Congenital Heart Disease Studies

Manchester University NHS Foundation Trust
2020-2022

Manchester University
2021

St Mary's Hospital
2006-2019

University of Manchester
2016

St. Mary's Hospital
2014

Royal Manchester Children's Hospital
2011

Liverpool Women's Hospital
2002

University of Liverpool
2002

The guideline is a revision of the 2004 British Committee for Standards in Haematology (BCSH) on transfusion neonates and older children (BCSH, 2004). Although there has been little evidence which to base paediatric clinical decisions past, have number studies national audits published over recent years that contribute decision-making this area. In addition changes other guidance, including management neonatal jaundice National Institute Health Clinical Excellence (NICE, 2010) requirement...

10.1111/bjh.14233 article EN British Journal of Haematology 2016-11-11

Aminoglycosides are commonly prescribed antibiotics used for the treatment of neonatal sepsis. The MT-RNR1 m.1555A>G variant predisposes to profound aminoglycoside-induced ototoxicity (AIO). Current genotyping approaches take several days, which is unfeasible in acute settings. To develop a rapid point-of-care test (POCT) before implementation this technology setting guide antibiotic prescribing and avoid AIO. This pragmatic prospective trial recruited neonates admitted 2 large intensive...

10.1001/jamapediatrics.2022.0187 article EN cc-by JAMA Pediatrics 2022-03-21

<h3>Aims</h3> Conventional teaching in neonatology is that open cranial sutures protect newborns from brain herniation secondary to raised intracranial pressure. This case series aims disseminate observations a tertiary neonatal centre of following hypoxic-ischaemic injury. <h3>Methods</h3> A retrospective review notes patients admitted the intensive care unit who were found have on MRI scan was performed using Badger. Their clinical history and imaging reports recorded. literature search...

10.1136/archdischild-2017-313087.479 article EN 2017-05-01

<h3>Background</h3> We have a regular weekly programme of simulation within the Neonatal Unit. These sessions involve nursing and medical staff are well received valued by team. However, currently take place in an education room, rather than in-situ. felt that our would benefit from moving to in-situ approach as this increase realism for participating staff, allow us detect latent safety threats. <h3>Risk assessment</h3> Use 'real' equipment: there been many articles reviewing aspects...

10.1136/bmjstel-2019-aspihconf.69 article EN 2019-11-01

<h3>Background</h3> Severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) and its pandemic disease have provided unprecedented challenges to medical treatment. To date there has been little definitive evidence of vertical transmission SARS-CoV-2 from mothers foetuses/neonates during pregnancy delivery. There is biological plausibility for in-utero infection the foetus with virus as previously demonstrated in placentae amniotic fluid. Goh et al's meta-analysis reports pooled incidence...

10.1136/archdischild-2021-rcpch.737 article EN other-oa Abstracts 2021-09-30

<h3>Introduction</h3> Asymptomatic cardiac murmurs are commonly detected on newborn examination. These babies frequently referred to paediatric cardiology services. To reduce waiting time for evaluation of these neonates, a neonatologist run echocardiography clinic was set up. <h3>Aim</h3> analyse the disease burden and diagnosis neonates neonatal in Level 3 NICU over 2 year period. <h3>Methods</h3> Retrospective analysis contemporaneously collected data infants who attended from January...

10.1136/archdischild-2014-306576.92 article EN Archives of Disease in Childhood Fetal & Neonatal 2014-06-01

<h3>Aims</h3> to ascertain the incidence, outcome of babies undergoing neonatal exchange blood transfusions (EBT) in UK and Ireland during a 13month period between 1<sup>st</sup> October 2014 31<sup>st</sup> 2015. <h3>Methods</h3> Data capture uses standard British Paediatric Surveillance Unit methodology; details study protocol are available at www.rcpch.ac.uk/bpsu/ebt"&gt;http://www.rcpch.ac.uk/bpsu/ebt"&gt;www.rcpch.ac.uk/bpsu/ebt <h3>Results</h3> In 13months reporting, 157 cases were...

10.1136/archdischild-2016-310863.419 article EN Archives of Disease in Childhood 2016-04-01

<h3>Introduction</h3> There are frequent situations in which our infants requiring face mask ventilation ('Neopuffing'). Traditional 'Neopuffing' of a non-intubated infant involves applying the and Neopuff with their usual position incubator - at 90 degrees to staff member administering breaths (figure 1). <h3>Aims</h3> To evaluate if there is difference between peak inspiratory pressure (PIP) achieved when Neopuffing in-line or member. members consider manouevre themselves so, how long...

10.1136/bmjstel-2019-aspihconf.33 article EN Oral Presentations 2019-11-01

<h3>Background</h3> Serious Hazards of Transfusion (SHOT) is the UK independent, professionally-led haemovigilance scheme which has collected and analysed anonymised reports on adverse events reactions following blood transfusion since 1996. These include transfusion-related deaths major morbidity. <h3>Objectives</h3> Where systematic risks issues are identified, SHOT produces recommendations to improve patient safety. <h3>Methods</h3> publishes an Annual Report; 2008 this included a...

10.1136/archdischild-2021-rcpch.322 article EN Abstracts 2021-09-30
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