- Mass Spectrometry Techniques and Applications
- Advanced Proteomics Techniques and Applications
- Chemical synthesis and alkaloids
- Electrolyte and hormonal disorders
- Microbial Natural Products and Biosynthesis
- Inorganic Chemistry and Materials
- Antibiotics Pharmacokinetics and Efficacy
- Pesticide Residue Analysis and Safety
- Hydrogen Storage and Materials
- Analytical Chemistry and Chromatography
- Fungal Biology and Applications
- Redox biology and oxidative stress
- Pharmacological Effects and Assays
- Fungal and yeast genetics research
- Metabolomics and Mass Spectrometry Studies
- Genomics, phytochemicals, and oxidative stress
- RNA Research and Splicing
- Analytical Methods in Pharmaceuticals
Indiana University – Purdue University Indianapolis
2010-2013
Indiana University School of Medicine
2010-2013
Sungkyunkwan University
2006
Samsung Medical Center
2006
Multiple reaction monitoring (MRM) mass spectrometry coupled with stable isotope dilution (SID) and liquid chromatography (LC) is increasingly used in biological clinical studies for precise reproducible quantification of peptides proteins complex sample matrices. Robust LC-SID-MRM-MS-based assays that can be replicated across laboratories ultimately laboratory settings require standardized protocols to demonstrate the analysis platforms are performing adequately. We developed a system...
The utility of mass spectrometry-(MS-) based proteomic platforms and their clinical applications have become an emerging field in proteomics recent years. Owing to its selectivity sensitivity, MS has a key technological platform research. Using this platform, large number potential biomarker candidates for specific diseases been reported. However, due lack validation, none approved use settings by the Food Drug Administration (FDA). Successful candidate verification validation will...