About
Contact & Profiles
A5037022281
Research Areas
- Glioma Diagnosis and Treatment
- Nanoplatforms for cancer theranostics
- Cancer Research and Treatments
Barrow Neurological Institute
2022
New approaches for the management of glioblastoma (GBM) are an urgent and unmet clinical need. Here, we illustrate that efficacy radiotherapy GBM is strikingly potentiated by concomitant therapy with arginine-depleting agent ADI-PEG20 in a non-arginine-auxotrophic cellular background (argininosuccinate synthetase 1 positive). Moreover, this combination led to durable complete radiological pathological response, extended disease-free survival orthotopic immune-competent model GBM, no...
10.1172/jci142137
article
EN
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Journal of Clinical Investigation
2022-02-03
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