- Trauma Management and Diagnosis
- Vascular Procedures and Complications
- Pleural and Pulmonary Diseases
- Trauma and Emergency Care Studies
- Central Venous Catheters and Hemodialysis
- Cardiac Arrhythmias and Treatments
- Pneumothorax, Barotrauma, Emphysema
- Cancer-related molecular mechanisms research
- Pelvic and Acetabular Injuries
- Tracheal and airway disorders
- Nitric Oxide and Endothelin Effects
- MicroRNA in disease regulation
- Congenital Diaphragmatic Hernia Studies
- Cardiac Arrest and Resuscitation
- Security and Verification in Computing
- Ultrasound in Clinical Applications
- Electric Power Systems and Control
- Parallel Computing and Optimization Techniques
- Cavitation Phenomena in Pumps
- Control Systems in Engineering
- Mesenchymal stem cell research
- Wnt/β-catenin signaling in development and cancer
- Infrastructure Maintenance and Monitoring
- Sensorless Control of Electric Motors
- Liver physiology and pathology
Yonsei University
2014-2024
Wonju Severance Christian Hospital
2015-2024
Electronics and Telecommunications Research Institute
2016
There is an increasing incidence of mortality among trauma patients; therefore, it important to analyze the epidemiology in order prevent death. The authors reviewed retrospectively at a regional emergency center Korea and evaluated main factors that led trauma-related deaths.A total 17007 patients were registered registry Wonju Severance Christian Hospital from January 2010 December 2012.The mean age was 35.2 years old. most frequent mechanism blunt injury (90.8%), as well slip-and-fall...
Background/Introduction: Odontogenic infection is one of the main etiologies deep neck (DNI). However, relationship between chronic periodontitis (CP) and incidence DNI has not been examined. This study aimed to evaluate peritonsillar abscess (PTA) after CP. Methods: The Korean National Health Insurance Service-National Sample Cohort 2002-2019 was used. In Study I, 4585 PTA patients were matched with 19,340 control I participants. A previous history CP for 1 year collected, odds ratios (ORs)...
Placental transmogrification is a very rare lung disease, where the alveoli resemble chorionic villi of placenta, and this change characteristic finding.A 31-year-old female patient presented with cough dyspnea that had begun 2 weeks prior to admission.Along giant bulla found in left upper field, subsegmental consolidation was also identified lingular segment on plain chest radiograph CT scan.Wedge resection performed remove bulla.Pathologic examination resected revealed destruction normal...
Interferon (IFN)-β and/or tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) secreted by adipose tissue-derived mesenchymal stem cells (ASCs) have been proposed as key mechanistic factors in anti-cancer efficacy lung cancer and breast cells, where they act through paracrine signaling.We hypothesized that IFN-β TRAIL produced ASCs suppress proliferation of hepatocellular carcinoma (HCCs).The present study evaluated the effects on HCCs vitro.We found indirect co-culture with...
Primary thymic mucinous adenocarcinoma is an extremely rare aggressive subtype of carcinoma. With a review literatures, only nine cases have been reported up to present. A 36-year-old woman was admitted for further evaluation and treatment mediastinal mass. The patient had no medical history cancer. clinicoradiological examination disclosed tumor elsewhere. After the surgical excision mass, it grossly round semi-solid mass with mucin-filled cystic areas. Microscopically solid areas showed...
Background Early detection of inner ear cell damage can reduce the chances permanent to hearing ability. However, current methods detect only after patient has lost MicroRNA expression levels in circulating systems are affected diseases or conditions arising from distant lesions. Therefore, microRNA could be one best ways obtain information on inaccessible lesion sites.Aims/objectives This study aims establish a method for monitoring idiopathic sudden sensorineural loss (ISSNHL) by analyzing...
Fibroblast growth factor 21 (FGF21) is a crucial metabolic regulator, with multiple favorable effects on glucose homeostasis and lipid metabolism. Since serum FGF21 level has been implicated as potential marker for the early identification of syndrome (MetS), we investigated association between development MetS in population-based prospective study. We conducted study 221 randomly sampled adults without from general cohort who were examined 2005-2008 (baseline) 2008-2011 (follow-up)....
Elevated plasma concentration of native low-density lipoprotein (nLDL) is associated with vascular smooth muscle cell (VSMC) activation and cardiovascular disease. We investigated the mechanisms superoxide generation its contribution to pathophysiological proliferation in response nLDL stimulation. Lucigenin-induced chemiluminescence was used measure nLDL-induced production human aortic cells (hAoSMCs). Superoxide increased by nicotinamide adenine dinucleotide phosphate (NADPH) decreased...
Primary spontaneous pneumothorax (PSP) is a pleural disease that abruptly affects healthy adolescents and young adults, representing common thoracic disorder in this age group. This study aimed to investigate the necessity of preoperative chest tube insertion patients with PSP re-evaluate current clinical treatment approaches. A retrospective review medical records was conducted for children adults aged 14–30 years, diagnosed who underwent Video-assisted thoracoscopic surgery (VATS) between...
Abstract: Esophageal perforation is a very rare occurrence because accidental swallowing of foreign bodies uncommon in adults. Thus, due to body and subsequent development mediastinitis rarely encountered by physicians. We experienced such case described an adult male patient who had perforated esophagus after accidentally mussel shell. The visited our emergency department complaining painful dysphagia for 4 days. A review history revealed that he consumed spicy seafood noodle soup...
Sternal fractures are relatively rare, and caused mainly by blunt anterior chest wall trauma. In most cases, sternal treated conservatively. However, if the patient exhibits problematic symptoms such as intractable pain or bony crepitus due to instability, surgical correction is indicated. But no consensus exists regarding appropriate method. We analyzed results of fixation in cases fracture order identify which method led best outcomes.We retrospectively reviewed medical records patients...
Currently, safety pharmacological tests for the central nervous system depend on animal behavioral analysis. However, due to subjectivity of analysis and differences between species, there is a limit appropriate toxicity assessment, therefore new neurotoxicity assessment that can simulate human required.In our study, we developed an in vitro focusing neuronal function. To minimize species fast screening, hiPSC-derived neurons microelectrode array (MEA) could simultaneously measure action...
In cases of chest trauma, computed tomography (CT) can be used alongside anteroposterior (AP) radiography and physical examination during initial evaluation. Performing a CT scan may difficult if patient has unstable vital signs. contrast, not always reliably diagnose nonmarked pneumothorax or extensive subcutaneous emphysema.This study aimed to determine the agreement between findings in patients with blunt trauma. The also occurrence occult clarify proportion emphysema detected through CT,...
Pulmonary Langerhans cell histiocytosis is an uncommon diffuse cystic lung disease in adults. In rare cases, it can involve extrapulmonary organs and lead to endocrine abnormalities such as central diabetes insipidus. A 42-year-old man presented with polyphagia polydipsia, well a dry cough dyspnea on exertion. Magnetic resonance imaging of the hypothalamic-pituitary system failed show posterior pituitary, which typical finding patients This condition was confirmed by water deprivation test,...
Although protein kinase C (PKC) regulates various biological activities, including cell proliferation, differentiation, migration, tissue remodeling, gene expression, and death, the antifibrotic effect of PKC in myofibroblasts is not fully understood. We investigated whether 12-O-tetradecanoylphorbol-13-acetate (TPA), a activator, reduced activation hepatic stellate cells (HSCs) explored involvement Hippo pathway transcriptional coactivator YAP. analyzed TPA on proliferation expression...
Blunt abdominal trauma may cause peripheral vascular injuries. However, blunt rarely results in injuries to the external iliac and common femoral arteries, which often stem from regional bone fractures. Here, we present case of a patient who had experienced lower groin area three months before presenting hospital, but these did not involve fractures been managed conservatively. The came hospital because left leg claudication that gradually became severe. Computed tomography angiography...
Unlike hard disk drive (HDD)-based storage systems, NAND flash memory-based systems require an additional layer called the translation (FTL) between file system and devices. The FTL helps use memory in same way as HDD by using address mapping function. However, this function can produce a side effect of delaying physical erasure point data when deleting data. In paper, we analyze time delay phenomenon from device that uses propose anti-forensic deletion scheme, which minimize time....
Pneumothorax refers to the abnormal presence of air in thoracic cavity. Pulmonary emphysema (PE) is often detected during computed tomography (CT), one radiological investigations used diagnose pneumothorax and devise treatment plans former or current smokers who present with pneumothorax. However, there are few reports that describe recurrence rate risk factors associated patients PE pneumothorax.This study retrospectively cross-sectional analyzed medical records 164 diagnosed their first...
<title>Abstract</title> <bold>Background</bold>: Among patients with trauma, those self-harm show different characteristics, such as frequency, damage area, and degree of from who experienced general accidents. In cases severe injuries, it is difficult to conduct accurate imaging tests during initial treatment, making predict the exact area damage make decisions for definitive care. Identifying correlations betweendamage can help aid in treatment. We aimed identify differences...
Objective: Previous studies have reported controversial results on the association between gout and risk of cancer. This study aimed to investigate relationship incidence head neck cancer (HNC). Methods: The data participants who underwent health checkups in 2009 were analyzed using National Health Insurance Database South Korea. A total 14,348 HNC patients 57,392 control for a prior history gout. Overlap weighting was applied, odds ratios (ORs) analyzed. overlap-weighted model adjusted...
Iatrogenic vascular injuries may occur during venipuncture, arterial cannulation, or catheterization procedures. Brachial arteriovenous fistula (AVF) resulting from antecubital access is rare and develops slowly. We report the case of an 18-year-old man who had developed iatrogenic brachial AVF. He a history several venipunctures in left arm at age 10 months. Doppler ultrasonography computed tomographic angiography were used to establish diagnosis AVF, surgical correction AVF was performed....
In patients with multiple trauma, a supine chest radiography [chest X-ray (CXR)] is preferred over erect CXR. However, this method has limitations in detecting post-traumatic pneumothorax. The use of computed tomography (CT) to detect traumatic pneumothorax well known. that not detected before CT scan known as an occult (OP), and it can cause serious complications the patient. This study sought evaluate frequency risk factors for OP trauma patients.Patients who suffered thoracic at Level 1...
Background: Totally implantable access port (TIAP) provides reliable, long term vascular with minimal risk of infection and allows patients normal physical activity. With wide use ports, new complications have been encountered. We analyzed TIAP related evaluated the outcomes two different percutaneous routes to superior vena cava. Methods: All 172 who underwent insertion internal jugular approach (Group 1, n = 92) subclavian 2, 79) between August 2011 May 2013 in a single center were...