A5101798766- Insect Resistance and Genetics
- Peptidase Inhibition and Analysis
- Insect-Plant Interactions and Control
- Insect and Pesticide Research
- Insect Pest Control Strategies
- Invertebrate Immune Response Mechanisms
- Fungal Infections and Studies
- Studies on Chitinases and Chitosanases
- Antimicrobial Peptides and Activities
- Glycosylation and Glycoproteins Research
- Plant and animal studies
- Protein Hydrolysis and Bioactive Peptides
- Clostridium difficile and Clostridium perfringens research
- Insect Utilization and Effects
- Medical Research and Treatments
- Cryospheric studies and observations
- interferon and immune responses
- Hemiptera Insect Studies
- Advanced SAR Imaging Techniques
- Geophysics and Gravity Measurements
- Viral Infectious Diseases and Gene Expression in Insects
- Insect symbiosis and bacterial influences
- Insect behavior and control techniques
- Gut microbiota and health
- Cholinesterase and Neurodegenerative Diseases
Hunan Agricultural University
2016-2025
Guangzhou Medical University
2025
China Tobacco
2025
Third Affiliated Hospital of Guangzhou Medical University
2025
Yueyang Changling Equipment Research Institute (China)
2024
Central South University
2023
Peking University
2019
Peking University Third Hospital
2019
The Ohio State University
2016
Chinese Academy of Agricultural Sciences
2012
The larval midgut of diamondback moth, Plutella xylostella, is a dynamic tissue that interfaces with diverse array physiological and toxicological processes, including nutrient digestion allocation, xenobiotic detoxification, innate adaptive immune response, pathogen defense.Despite its enormous agricultural importance, the genomic resources for P. xylostella are surprisingly scarce.In this study, Bt resistant strain was subjected to in-depth transcriptome analysis identify genes gene...
The effects of feeding on insect larvae treated with pesticide the biological and biochemical characteristics Arma chinensis were investigated. In F0 generation, developmental duration preoviposition period shortened, average number eggs laid was reduced, net reproductive rate mean generation time significantly lower in treatment group compared to those control group. by F1 A. intrinsic rates increase, finite increase than activities CarE GST induced, while activity AChE inhibited trypsin...
To identify potential therapeutic targets and evaluate the safety profiles for Idiopathic Pulmonary Fibrosis (IPF) using a comprehensive multi-omics approach. We integrated genomic transcriptomic data to IPF. First, we conducted transcriptome-wide association study (TWAS) Omnibus Transcriptome Test Expression Reference Summary (OTTERS) framework, combining plasma expression quantitative trait loci (eQTL) with IPF Genome-Wide Association Studies (GWAS) summary statistics from Global Biobank...
Bacillus thuringiensis (Bt) produce diverse insecticidal proteins to kill insect pests. Nevertheless, evolution of resistance Bt toxins hampers the sustainable use this technology. Previously, we identified down-regulation a trypsin-like serine protease gene PxTryp_SPc1 in midgut transcriptome and RNA-Seq data laboratory-selected Cry1Ac-resistant Plutella xylostella strain, SZ-R. We show here that reduced expression significantly caseinolytic trypsin activities affecting Cry1Ac protoxin...
Abstract Bacillus thuringiensis (Bt) is widely used as a biopesticide worldwide. To date, at least eight pest species have been found to be resistant Bt in the field. As first that was reported having resistance field, considerable research has done on mechanisms of Plutella xylostella . However, whether acquisition by P. comes fitness cost also valuable question. In this study, Aminopeptidase‐N 2 ( APN2 ), Cry toxin receptor gene , knocked down RNA interference, resulting improved Cry1Ac....
Flonicamid is a selective insecticide effective against piercing-sucking insects. Although its molecular target has been identified in other species, the specific effects and detailed mechanism of action
Abstract This study determined the resistance to five different insecticides, and assessed change in enzymes three Myzus persicae populations Liuyang, Guiyang, Longshan tobacco ( Nicotiana tabacum L.)‐growing areas Hunan province, China. The activities of detoxification, protective, digestive were using biochemical analysis. Results indicated that Liuyang population had high Imidacloprid, moderate Aacetamiprid Cyhalothrin. showed low Phoxim, while Guiyang both exhibited reduced...
Abstract The cloning, expression in vitro, and characterization of two aminopeptidase Ns (APN5s APN2s) isolated from the midgut Cry1Ac‐resistant (R) susceptible (S) strains Plutella xylostella larvae are presented this paper. deduced amino acid sequences APN5s included C‐terminal GPI‐modification sites, gluzincin motif GATEN, three N‐glycosylated sites; those APN2s had no GAMEN, four sites. O‐glycosylated sites were not predicted for either APN. Because APN2R APN2S cDNAs contained same...
At present, chemical pesticides remain the main approach for controlling Pieris rapae (L.) (Lepidoptera: Pieridae). This research proposes a novel laser irradiation method managing P. larvae as an alternative to control. The effectiveness of and influencing factors lasers were studied estimate optimal parameter combinations. Tests using antifeedant effect mortality dependent variables showed that power, area, opening time position positively correlated with effect. parameters each factor...
The population dynamics of main tobacco pests were evaluated between 2010 and 2012 in China using systematic field monitoring pheromone lures. Winged Myzus persicae peaked at 156 late April/early May gradually decreased, eventually disappearing by early June. Agrotis ipsilon, which 23 2011, was the pest during seedling stage, first appearing February/early March but rarely causing harm before mid-May. Overwintered Helicoverpa armigera appeared end March, 22 from April to June disappeared...
Abstract Gut microbiota may have therapeutic effects on inflammatory bowel disease (IBD). Regulating intestinal through Lactiplantibacillus plantarum ( L. ) and faecal transplantation (FMT) is a novel approach to treating IBD. This study aimed explore the effect of FMT pretreatment in alleviating colitis mice. Five groups mice (n = 6 per group) were included: CON group, DSS group (dextran sodium sulphate-induced mice), LP-DSS (colitis given strain 5% DSS), DSS-FMT (mice pretreated with...
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The endoparasitoid body size hypothesis suggests that the of larvae develop in a single host should be subject to trade-off: larger could lead increase overall fitness but simultaneously risk resource depletion and starvation, resulting just below holding capacity. However, this has not been rigorously tested using mathematical models thus far. camellia weevil, C.styracis (Coleoptera: Curculionidae), is notorious pest attacking fruits Camellia oleifera Abel. C. meiocarpa Hu., which within...
Abstract Previous studies on Bacillus thuringiensis (Bt) resistance in the diamondback moth (DBM) Plutella xylostella have often focused receptor proteins gut. In recent years, many indicated that insect to Bt is related immune system. Moreover, our group demonstrated expression of peptidoglycan recognition protein (PGRP) genes, which are located upstream humoral system signalling pathway, significantly different between Cry1Ac‐resistant and Cry1Ac‐susceptible strains DBM. Thus, whether...