Maria Asuncion A. Silvestre

ORCID: 0000-0001-8158-0198
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About
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Research Areas
  • Global Maternal and Child Health
  • Health Systems, Economic Evaluations, Quality of Life
  • Clinical practice guidelines implementation
  • Child Nutrition and Water Access
  • Health Promotion and Cardiovascular Prevention
  • Breastfeeding Practices and Influences
  • Child Nutrition and Feeding Issues
  • Infant Development and Preterm Care
  • Clinical Nutrition and Gastroenterology
  • Neonatal Respiratory Health Research
  • Maternal and Perinatal Health Interventions
  • Viral gastroenteritis research and epidemiology
  • Meta-analysis and systematic reviews
  • Nutritional Studies and Diet
  • Birth, Development, and Health
  • Child and Adolescent Health
  • Prenatal Substance Exposure Effects
  • Pregnancy and Medication Impact
  • Viral Infections and Outbreaks Research
  • Prenatal Screening and Diagnostics
  • Healthcare Quality and Management
  • Maternal and Neonatal Healthcare
  • Infant Nutrition and Health
  • Mosquito-borne diseases and control
  • Colorectal Cancer Screening and Detection

University of the Philippines Manila
2010-2022

Ospedale Pediatrico Giovanni XXIII
2022

Universidade Evangelica de Goiás
2020

University of Asia and the Pacific
2016-2020

Philippine General Hospital
2004-2016

University of the Philippines System
2004-2012

Hutzel Women's Hospital
1996-1997

Wayne State University
1996-1997

Children's Hospital of Michigan
1997

Abstract Clinical question What is the role of remdesivir in treatment severe covid-19? This guideline was triggered by ACTT-1 trial published New England Journal Medicine on 22 May 2020. Current practice Remdesivir has received worldwide attention as a potentially effective for covid-19. After rapid market approval US, already being used clinical practice. Recommendations The panel makes weak recommendation use covid-19 while recommending continuation active enrolment patients into ongoing...

10.1136/bmj.m2924 article EN BMJ 2020-07-30

A deadly nosocomial outbreak in a Philippine hospital drew nationwide attention to neonatal sepsis. Together with specific infection control measures, interventions that protect newborns against infection-related mortality include drying, skin-to-skin contact, delayed cord clamping, breastfeeding initiation and bathing. This evaluation characterized care the first hours of life intent drive policy change, strategic planning reform.Trained physicians observed 481 consecutive deliveries 51...

10.1111/j.1651-2227.2011.02215.x article EN other-oa Acta Paediatrica 2011-03-07

Maternal mortality has declined by nearly half since 1990, but over a quarter million women still die every year of causes related to pregnancy and childbirth. Maternal-health targets are falling short the 2015 Millennium Development Goals post-2015 Agenda is emerging. In connection with this, setting global research priorities for next decade now required. We adapted methods Child Health Nutrition Research Initiative (CHNRI) identify set maternal perinatal health period 2025. Priority...

10.1186/1742-4755-11-61 article EN cc-by Reproductive Health 2014-08-07

To explore the association between early essential newborn care (EENC) policy, practice and environmental interventions breastfeeding outcomes.Cross-sectional observational study.150 national, provincial district hospitals implementing EENC in eight countries East Asia Pacific.1383 maternal interviews, chart reviews assessments during 2016 2017.Exclusive (EBF), that is, feeding only breastmilk without other food or fluids since birth before discharge, and, initiation, skin-to-skin contact...

10.1136/bmjgh-2020-002581 article EN cc-by-nc BMJ Global Health 2020-08-01

Although age is a strong risk factor for atherosclerosis, it unclear whether may directly influence the process of atherogenesis. We, therefore, performed several studies in young (2-4 months old), mature (10-14 and old (20-22 old) mice to determine if rate aortic lesion formation increases with age, this related oxidative stress or vascular cell adhesion molecule (VCAM-1) expression wall. In chow-fed low-density lipoprotein receptor-deficient (LDLR-/-) mice, plasma total cholesterol levels...

10.1093/gerona/55.2.b85 article EN The Journals of Gerontology Series A 2000-02-01

To determine whether intrapartum and newborn care practices improved in 11 large hospitals between 2008 2015.Secondary data analysis of observational assessments conducted 2015.Eleven government from five regions the Philippines.One hundred seven randomly sampled postpartum mother-baby pairs 106 mothers prior to discharge after delivery.A national initiative improve quality starting 2009 through development a standard package services, practice-based training, formation multidisciplinary...

10.1093/intqhc/mzy049 article EN International Journal for Quality in Health Care 2018-03-22

Background. On 8 November 2013, supertyphoon Haiyan made landfall in the Philippines, severely disrupting health service delivery. Reestablishment of essential services for birthing mothers and their newborns became high priority. Methodology. Following a baseline assessment, an Essential Intrapartum Newborn Care (EINC) training package was implemented posttraining assessments (1 3 months after training) were undertaken. Results. Baseline (<mml:math...

10.1155/2016/6264249 article EN cc-by BioMed Research International 2016-01-01

Meconium drug analysis is a new and sensitive test for detecting the intrauterine exposure of infants to drugs abuse. To explore other potential, diagnostic use test, we studied, in timed pregnant rats, relationship between timing, dosage, duration morphine administration dam concentration morphine, analyzed by radioimmunoassay, their pups’ meconium. The term ‘meconium’ refers both intestine its contents. Due minute size intestines, intestinal contents were not separated from intestines....

10.1159/000244473 article EN Neonatology 1997-01-01

Summary Purpose The Republic of the Philippines has recently enacted Universal Health Care Law, which mandates Department (DOH) to operationalize evidence‐based clinical practice guideline (CPG) development. As a baseline foregoing task, aim this study was appraise methodological quality CPGs previously developed and currently being disseminated in Philippines. A multimethod search for implemented. were independently evaluated using modified version Knowledge Management Plus CPG appraisal...

10.1002/hpm.2886 article EN The International Journal of Health Planning and Management 2019-08-21

Fetal sexing from maternal plasma is aimed at early determination of fetal sex, and it possible to detect in the specific alleles fetus, which are inherited paternally.In this case, Y chromosome sequences amplified by PCR.This PCR technique a useful tool for determining with no risk fetus.We determined sex molecular different gestational stages compared results obstetric ultrasound information, pregnant women between 8th 13th weeks gestation, who were over 18 years age.Among 32 samples...

10.4238/gmr18559 article EN Genetics and Molecular Research 2020-01-01
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