A5029432402- Adipokines, Inflammation, and Metabolic Diseases
- Adipose Tissue and Metabolism
- Tissue Engineering and Regenerative Medicine
- Cardiovascular Disease and Adiposity
- Electrospun Nanofibers in Biomedical Applications
- Bone Tissue Engineering Materials
- Infectious Aortic and Vascular Conditions
- Diet and metabolism studies
- Meat and Animal Product Quality
- Muscle metabolism and nutrition
- Sirtuins and Resveratrol in Medicine
- Protein Hydrolysis and Bioactive Peptides
- Endoplasmic Reticulum Stress and Disease
- Biochemical effects in animals
Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán
2017-2024
Abstract Subcutaneous (SAT) and visceral (VAT) adipose tissues stores excess energy as triglycerides synthesize adiponectin to prevent ectopic lipid accumulation lipotoxicity. During obesity, an impairment in the capacity of SAT store is associated with increased free fatty acids (FFA) release, leading VAT hypertrophy hepatic skeletal muscle Endoplasmic reticulum (ER) stress unfolded protein response (UPR) may be involved dysfunction during obesity. The objectives this study were assess UPR...
Pecans (Carya illinoinensis) are considered a functional food due to the high content of polyunsaturated fatty acids, dietary fiber and polyphenols. To determine effect whole pecans (WP) or pecan polyphenol (PP) extract on development metabolic abnormalities in mice fed high-fat (HF) diet, we C57BL/6 with Control diet (7% fat), HF (23% containing 30% WP an supplemented 3.6 6 mg/g PP for 18 weeks. Supplementation reduced fat mass, serum cholesterol, insulin HOMA-IR by 44, 40, 74 91%,...
Goat’s milk is a rich source of bioactive compounds (peptides, conjugated linoleic acid, short chain fatty acids, monounsaturated and polyunsaturated polyphenols such as phytoestrogens minerals among others) that exert important health benefits. However, goat’s composition depends on the type food provided to animal thus, abundance in dietary sources goat feed. The metabolic impact during challenges high-fat (HF) diet has not been explored. Thus, we evaluated effect from goats fed...
Reconstruction of bile ducts damaged remains a vexing medical problem. Surgeons have few options when it comes to long segment reconstruction the duct. Biological scaffolds decellularized biliary origin may offer an approach support replace ducts. Our objective was obtain extracellular matrix scaffold derived from porcine extrahepatic (dECM-BD) and analyze its biological biochemical properties. The efficiency tailored perfusion decellularization process assessed through histology stainings....
This work presents strong evidence supporting the use of decellularized human iliac arteries combined with adipose tissue-derived stem cells (hASCs) as a promising alternative for vascular tissue engineering, opening path to future treatments peripheral artery disease (PAD). PAD is progressive condition high rates amputation and mortality due ischemic damage limited graft options. Traditional synthetic grafts often fail poor integration, while autologous may be unsuitable patients...