A5035806013- Cardiovascular Effects of Exercise
- Cardiac Imaging and Diagnostics
- Coronary Interventions and Diagnostics
- Cerebrovascular and Carotid Artery Diseases
- Cardiac electrophysiology and arrhythmias
- Cardiovascular Function and Risk Factors
- Cardiac Arrhythmias and Treatments
- Atrial Fibrillation Management and Outcomes
- Viral Infections and Immunology Research
- Cardiovascular Health and Disease Prevention
- Acute Myocardial Infarction Research
- Sports injuries and prevention
- Eosinophilic Disorders and Syndromes
- Cancer and Skin Lesions
- Lipoproteins and Cardiovascular Health
- Cardiomyopathy and Myosin Studies
- Sympathectomy and Hyperhidrosis Treatments
- Cardiovascular Issues in Pregnancy
- Atherosclerosis and Cardiovascular Diseases
- Cardiovascular Disease and Adiposity
- Genetic and rare skin diseases.
- Epilepsy research and treatment
- Advanced MRI Techniques and Applications
- Antiplatelet Therapy and Cardiovascular Diseases
- Cytomegalovirus and herpesvirus research
Aarhus University Hospital
1998-2015
Aalborg University
2014
Odense University Hospital
2014
Taipei Institute of Pathology
2012
Aarhus University
1999-2012
Aalborg University Hospital
2009-2010
Background and Purpose— Information about the expression of atherosclerosis in different arteries is important. The impact cardiovascular risk factors artery-related, assessment arterial structure function peripheral are increasingly used as surrogate markers for coronary developing heart attack. Methods— In an autopsy study, we analyzed coronary, carotid superficial femoral from 100 individuals (70 men; 20 to 82 years age) which 27 died atherosclerosis. Microscopic sections (n=4756) were...
Results: Sudden unexpected death in epilepsy (SUDEP) gains more and acknowledgment across the various interdisciplinary fields. Accordingly, we performed a prospective setting case-control study of all SUDEP cases well-defined part Denmark (Northern Jutland), between January 1998 September 2000. We attempted to look into cardiopathologic mechanism behind this phenomenon by assessing degree myocardial fibrosis patients versus controls. The histologic evaluation was possible 65% (15/23) whose...
Arrhythmogenic cardiomyopathy (AC) is a hereditary cardiac condition associated with ventricular arrhythmias, heart failure, and sudden death. The disease most often caused by mutations in the desmosomal gene for plakophilin-2 (PKP2), which expressed both myocardial epidermal tissue. This study aimed to investigate protein expression tissue of patients AC carrying PKP2 elucidate whether keratinocytes same individuals exhibited similar pattern expression.Direct sequencing 5 genes 71 unrelated...
Mutations in the gene for desmoplakin ( DSP ) may cause arrhythmogenic right ventricular cardiomyopathy ARVC and Carvajal syndrome CS ). Desmoplakin is part of all desmosomes, which are abundantly expressed both myocardial epidermal tissue serve as intercellular mechanical junctions. This study aimed to investigate protein expression patients carrying mutations order elucidate potential molecular disease mechanisms. Genetic investigations identified three different heterozygous addition a...
Arrhythmogenic right ventricular cardiomyopathy (ARVC) is a hereditary cardiac condition associated with arrhythmias, heart failure, and sudden death. The most frequent ARVC genes encode desmosomal proteins of which mutations in desmoglein-2 (DSG2), account for 10%–20% cases. This study aimed to investigate how DSG2 contribute the pathogenesis ARVC. Initial mutation analysis 71 probands identified first family reported recessively inherited due missense mutation. In addition, three...
Using magnetic resonance imaging the effects of temperature, formalin fixation, and decalcification on size morphology atherosclerotic arteries were evaluated. Ten ex vivo carotid scanned fresh at body room temperature formalin-fixed decalcified temperature. Different spin-echo pulse sequences used absolute T2 values calculated. During processing for histopathology, contrast between arterial layers increased. From to there significant increases in (4%–7%), media (60→ 68 msec), fibrous plaque...
Objective: Noninvasive contrast-enhanced coronary computed tomography (CT) angiography enables distinction between calcified and noncalcified atherosclerotic plaques. However, separation of plaques into rupture prone lipid-rich stable fibrous subtypes is challenging because CT density the plaque, characterized by Hounsfield Units (HU), varies with intraluminal contrast acquisition protocol. This study aims at testing influence densities kV-settings on plaque values in vitro. Materials...
Eccrine angiomatous hamartoma is a rare benign cutaneous malformation with diverse clinical appearance, therefore likely to be misdiagnosed and underreported.A 44-year-old man presented congenital erythematous hyperhidrotic plaque on the left upper back measuring 18 x 25 cm. No pain or tenderness nor hypertrichosis were observed. Histopathology was consistent mucinous variant of eccrine hamartoma. Intralesional injection botulinum toxin type A greatly reduced localized sweating, improving...
A case of circulatory collapse due to severe heart failure is reported in a 52-year old male with autoimmune disorders the form type-1 diabetes, Graves' disease and total alopecia.Upon admission, patient had cardiac index 0.9 l/min/m(2), mixed venous saturation 29% left ventricular ejection fraction 5%. The condition was refractory treatment inotropic agents required mechanical cardiopulmonary support. Endomyocardial biopsies revealed extensive giant cell myocarditis (GCM). Immunosuppressant...
Background: Arrhythmogenic cardiomyopathy (AC) is a hereditary cardiac condition associated with ventricular arrhythmias, heart failure and sudden death. The disease most often caused by mutations in the desmosomal gene for plakophilin-2 (PKP2), which expressed both myocardial epidermal tissue. It was aim of this study to investigate protein expression tissue ARVC patients carrying PKP2 elucidate if keratinocytes same individuals exhibited similar pattern expression. Methods Results: Direct...