A5078113997- Genomics and Rare Diseases
- Neurobiology and Insect Physiology Research
- IL-33, ST2, and ILC Pathways
- PI3K/AKT/mTOR signaling in cancer
- Epigenetics and DNA Methylation
- Ginger and Zingiberaceae research
- Renal and related cancers
- Genetic Syndromes and Imprinting
- Glycosylation and Glycoproteins Research
- Genetic and Kidney Cyst Diseases
- Genetics and Neurodevelopmental Disorders
- Aquaculture Nutrition and Growth
- Asthma and respiratory diseases
- Genetic factors in colorectal cancer
- Exercise and Physiological Responses
- Aquaculture disease management and microbiota
- Helicobacter pylori-related gastroenterology studies
- Lysosomal Storage Disorders Research
- Mast cells and histamine
- Genetic Associations and Epidemiology
- Congenital heart defects research
- Adipose Tissue and Metabolism
Gansu University of Traditional Chinese Medicine
2025
Hunan Children's Hospital
2023-2025
Central South University
2025
Henan Normal University
2022
Asthma is one of the most common chronic respiratory diseases affecting children, and there currently no clear remedy. Immune cells play a key role in childhood asthma. Therefore, deeper investigation correlation between immune asthma could lead to better understanding asthma's origin, identification potential treatment targets, development personalized strategies. We used two-sample Mendelian randomization (MR) analysis investigate possible causal relationship total 731 cells, including B...
Abstract Introduction Nuclear receptor subfamily 2, group F, member 1 ( NR2F1 ) gene variations are associated with Bosch–Boonstra–Schaaf optic atrophy syndrome. The genotype correlates its phenotype; variants within the DNA-binding domain may cause severe psychomotor developmental disorders. However, mechanisms underlying these phenotypes remain unclear. Methods Whole-exome sequencing was performed on proband and her parents DNA. Candidate were verified by Sanger bioinformatics analyses....
Tea polysaccharides plays a role in lipid metabolism, antioxidant capacity and immunity of mammals. To investigate the functions tea on fish, common carp ( Cyprinus carpio L.) was selected as animal model this study. In our study, (45±0.71g) were randomly divided into four groups fed fodder with 50% carbohydrate. The orally administrated 0 mg/kg BW (control group), 200 (low-dose 400 (medium-dose group) 800 (high-dose polysaccharide for two week. At end experiment, serum glucose, TG, MDA...
As an endocrine organ, skeletal muscle secretes multiple myokines. Myonectin, a myokine, participates in lipid and glucose metabolism. To explore the functions of myonectin teleosts, gene was cloned from brain tissue grass carp. The open reading frame (ORF) isolated 813 bp, encoding 270 amino acids. Grass carp has four predicted domains: signal peptide, N-terminal domain (NTD), collagen protein domain, C1q/TNF-like domain. In addition, glycosylation sites conserved cysteine residues were...
Abstract Background Defects in the Golgi enzyme beta‐galactoside‐alpha‐2,3‐sialyltransferase‐III (ST3Gal‐III) caused by biallelic ST3GAL3 gene variants are associated with human neurodevelopmental disorders. Although have been linked to developmental and/or epileptic encephalopathy 15 (DEE15), their presence has only reported nine patients; however, real frequency may be masked insufficient screening. Methods Phenotypic information was collected from a male patient severe psychomotor delay...