A5071026869- Pancreatic function and diabetes
- Diabetes and associated disorders
- Diabetes Management and Research
- Renal Transplantation Outcomes and Treatments
- Diabetes Treatment and Management
- Nutrition and Health in Aging
- Hearing, Cochlea, Tinnitus, Genetics
- Ion Channels and Receptors
- SARS-CoV-2 and COVID-19 Research
- Botulinum Toxin and Related Neurological Disorders
- Vestibular and auditory disorders
- Pain Mechanisms and Treatments
- COVID-19 diagnosis using AI
- Diagnosis and treatment of tuberculosis
- Antioxidant Activity and Oxidative Stress
- Pain Management and Treatment
- SARS-CoV-2 detection and testing
- Legionella and Acanthamoeba research
- Ion Transport and Channel Regulation
- Genetics, Bioinformatics, and Biomedical Research
- Organ Transplantation Techniques and Outcomes
- Body Composition Measurement Techniques
- HIV-related health complications and treatments
- Retinal and Macular Surgery
- Animal testing and alternatives
University of Miami
2021-2025
Instituto Superior de Saúde do Alto Ave
2024
Centro Hospitalar Tondela-Viseu
2013-2022
Miami Transplant Institute
2021
Univates
2014-2015
Universidade Federal do Rio Grande do Sul
2012-2014
Universidade do Vale do Rio dos Sinos
2014
Hospital São Teotónio
2008-2011
Type 1 diabetes (T1D) is a complex metabolic autoimmune disorder that affects millions of individuals worldwide and often leads to significant comorbidities. However, the precise trigger autoimmunity disease onset remain incompletely elucidated. This integrative perspective article synthesizes cumulative role gene-environment interaction in pathophysiology T1D. Genetics plays T1D susceptibility, particularly at major histocompatibility (MHC) locus cathepsin H (CTSH) locus. In addition...
Malnutrition and chronic inflammation in dialysis patients negatively impact their survival prognosis, nutrients, such as omega-3 oils, are postulated to reduce proinflammatory response. In this randomized, double-blind, multicenter, placebo-controlled trial, we investigated the effects of flaxseed oil (FO) on inflammatory state with renal failure undergoing replacement therapy hemodialysis (HD). We hypothesized that FO supplementation lowers C-reactive protein (CRP) levels. One hundred...
SARS-CoV-2 pandemic has forced frequent testing of populations. It is necessary to identify the most cost-effective strategies for detection COVID-19 outbreaks. Nasopharyngeal samples have been used but require a healthcare professional collect sample and cause discomfort pain individual. Saliva suggested as an appropriate fluid diagnosis COVID-19. We investigated possibility using pools saliva detect in symptomatic asymptomatic patients. Two hundred seventy-nine were analyzed through RT-PCR...
Dysglycemia, affecting over 800 million people globally, poses a significant challenge to health systems and economies, contributing healthcare costs exceeding $966 billion annually. This practice paper presents strategic, multi-level framework addressing dysglycemia through evidence-based interventions. Effective measures include promoting low-glycemic diets, structured physical activity, continuous glucose monitoring technologies enhance self-management. Policy initiatives such as sugar...
The COVID-19 pandemic has underscored the need for efficient and non-invasive diagnostic tools early detection management. This study evaluated TERA breath analyzer (TERA.Bio®), a Real-Time High-Throughput Breathalyzer, SARS-CoV-2 detection. It aimed to validate implement TERA.Bio® of within university population compared RT-qPCR testing. Conducted at University Miami, this observational consisted two phases: validation phase longitudinal monitoring phase, using cross-sectional prospective...
Blood glucose monitoring constitutes a pivotal element in the clinical management of Type 1 diabetes (T1D), globally escalating metabolic disorder. Continuous (CGM) devices have demonstrated efficacy optimizing glycemic control, mitigating adverse health outcomes, and augmenting overall quality life for individuals afflicted with T1D. Recent progress field encompasses refinement electrochemical sensors, which enhances effectiveness blood monitoring. This empowers patients to assume greater...
Islet cell transplantation (ITx) is an effective therapeutic approach for selected patients with type 1 diabetes hypoglycemia unawareness and severe events. In organ transplantation, human leukocyte antigen (HLA) mismatching between donor recipient negatively impacts transplant outcomes. We aimed to determine whether HLA matching has impact on islet allograft survival. Forty-eight were followed up after at our institution from 2000 2020 in a retrospective cohort. Patients underwent...
Abstract Background Islet transplantation (ITx) has proved to be effective in preventing severe hypoglycemia and improving metabolic control selected subjects with type 1 diabetes. Long-term graft function remains a challenge. Estrogens have been shown protect β cells from stresses improve revascularization of transplanted human islets the mouse. We aimed evaluate influence sex allograft survival ITx recipients. Methods analyzed retrospective cohort recipients (n = 56) followed-up for up 20...
To evaluate the combined administration of propylthiouracil (PTU) and levothyroxine (LT4) in managing monocarboxylate transporter 8 (MCT8) deficiency identify optimal therapeutic dosages.
INTRODUCTION: Cardiovascular disease (CVD) is a major determinant of mortality in renal transplant recipients (RTR). Metabolic syndrome (MS) and chronic inflammation are currently considered non traditional risk factors for cardiovascular disease. This study evaluates the frequency these conditions their associations with graft function. OBJECTIVE: To evaluate prevalence metabolic function recipients. METHODS: A cross-sectional was carried out 200 RTR. MS defined by NCEP-ATP III criteria....
AIMS: To assess the prevalence of nutritional risk in hospitalized subjects and agreement diagnosis between five screening protocols. METHODS: A cross-sectional study included patients both genders, aged 18, admitted to hospital from January March 2013 Within first 48 hours admission, following protocols were applied: Mini Nutrition Assessment (MNA); Short Form (MNA-S); Subjective Global (ASG); Nutritional Risk Screening (NRS 2002); Malnutrition Universal Tool (MUST). The consist questions...
O estudo objetiva avaliar o estado nutricional e associá-lo à prevalência de doenças crônicas não transmissíveis (DCNT) em idosos. Trata-se um transversal constituído por 112 indivíduos, com idade superior a 60 anos, ambos os gêneros, participantes grupos da terceira do município Roca Sales-RS. Para avaliação nutricional, foram aferidas circunferência cintura (CC), peso estatura. Após, foi calculado índice massa corporal (IMC). Aplicou-se questionário para obtenção informações sobre estilo...