A5101964042- Inflammatory Bowel Disease
- Retinal Diseases and Treatments
- Anesthesia and Sedative Agents
- Cytokine Signaling Pathways and Interactions
- CAR-T cell therapy research
- Polyomavirus and related diseases
- IgG4-Related and Inflammatory Diseases
- Psoriasis: Treatment and Pathogenesis
- Gut microbiota and health
- Galectins and Cancer Biology
- Immune Response and Inflammation
- Cancer Research and Treatments
- NF-κB Signaling Pathways
- Pediatric health and respiratory diseases
- Glaucoma and retinal disorders
- Barrier Structure and Function Studies
- Neonatal Health and Biochemistry
- Natural product bioactivities and synthesis
- Neuroendocrine Tumor Research Advances
- Chronic Obstructive Pulmonary Disease (COPD) Research
- Helicobacter pylori-related gastroenterology studies
- Biliary and Gastrointestinal Fistulas
- Uterine Myomas and Treatments
- Optical Coherence Tomography Applications
- Ferroptosis and cancer prognosis
Capital Medical University
2021-2025
North Sichuan Medical University
2025
Nanchong Central Hospital
2025
Nanjing Drum Tower Hospital
2019-2024
Dongguan People’s Hospital
2024
Guiyang Medical University
2024
Shaanxi Provincial People's Hospital
2013-2023
Shanxi Medical University
2013-2023
China Medical University
2013-2022
Beijing Hospital of Traditional Chinese Medicine
2021
The current study aims to investigate the protective effects of Bifidobacterium infantis on abnormal immune response inflammatory bowel disease (IBD) in dextran sodium sulfate (DSS)-induced colitis.Eight-week-old BALB/c mice were separated into five groups at random (control, DSS, DSS+B9 [B. 1×109 CFU], DSS+B8 1×108 and DSS+B7 1×107 CFU]). Colitis was induced by 5% DSS ad libitum for 7 days, which time we assessed weight, activity index (DAI) score, histological damage score. nuclear...
Objective: To investigate the protective effects of Clostridium butyricum on epithelial barrier in dextran sodium sulfate (DSS)-induced colitis.Methods: Eight-week-old BALB/c mice were divided into a healthy control group and DSS-induced groups, including negative (normal saline), 5-aminosalicylic acid (5-ASA), C. group, 5-ASA + groups. Colitis was induced by 5% DSS ad libitum for 7 d. We assessed disease activity index (DAI), histological grading, ultrastructural changes transmission...
Relationship between visceral fat and development of uterine fibroids in adult women was investigated. A total 89 patients with treated the First Hospital Hebei Medical University from April 2016 to 2018 were enrolled. Another 81 healthy without receiving physical examination same period selected as control group. Self-designed questionnaires used investigate general conditions subjects, bioelectrical impedance analysis employed analyze obesity-related indicators, their correlation risk...
Artesunate (ART) is a semi‑synthetic derivative of artemisinin used in the treatment patients with malaria, which has also been reported to have immunoregulatory, anticancer and anti‑inflammatory properties. The aim present study was investigate possible beneficial effects ART on ulcerative colitis (UC) rats detect mechanisms underlying these effects. A UC rat model established using dextran sulfate sodium (DSS). Rats were randomly divided into following groups: Normal control, group,...
This study explored the link between clinical features, immune markers, and asthma-chronic obstructive pulmonary disease overlap (ACO), aiming to enhance diagnostic precision tailor treatment. The included 60 patients per group: COPD patients, ACO healthy controls. Biological indicators such as fractional exhaled nitric oxide (FeNO), eosinophils, immunoglobulin E (IgE), T helper (Th) 17 cell counts, regulatory T-cell (Treg) cytokine levels of interleukin-17 (IL-17) interleukin-10 (IL-10)...
The Abernethy malformation is a rare congenital defined by the presence of an extrahepatic portosystemic shunt. Although most patients are asymptomatic, clinical encephalopathy present in 15% cases. We patient with type 2 Aber-nethy malformation, hyperammonemia, and encephalopathy. Shunt closure was performed successfully using interventional angiography; however, hyperammonemia recurred 3 months later. diagnosis can be made easily, but ideal management strategy has not yet been established....
Abstract In vitro differentiated CD8+ T cells have been the primary focus of immunotherapy cancer with little on CD4+ cells. Immunotherapy involving in given after lymphodepleting regimens significantly augments antitumor immunity animals and human patients cancer. However, mechanisms by which lymphopenia adoptive cell therapy means properly differentiating are still emerging. We demonstrate that naïve tumor/self-specific naturally into helper type 1 (Th1) cytotoxic vivo caused regression...
To the Editors, Vedolizumab is a gut-selected humanized α4β7 integrin antibody, which reduces intestinal inflammation by inhibiting lymphocyte migration to gut. Recently, vedolizumab has been increasingly used in treatment of moderately severely active ulcerative colitis (UC). safety assessment showed high profile with low incidence rates serious infections, malignancy events, and <5% infusion-related reactions.1 The results from GEMINI long-term (LTS) study have further established its...
Inflammatory bowel disease (IBD) is an inflammatory that occurs to the intestinal tract. Many patients with IBD often develop anemia and receive oral iron supplementation. of them non-compliance therapy, but mechanisms are not well understood. We interrogated whether colonic epithelial overload impacts cell viability severity. observed increased expression importers accumulation in mature colonocytes dextran sulfate sodium (DSS)-induced acute colitis humans active colitis. Administration...
Objective To investigate the effect of γ-Vitamin E(γ-VitE) on levels IL-4, IL-13 in serum and bronchoalveolar lavage fluid mouse with asthma. Methods Thirty healthy Balb/c mice were randomly divided into 3 groups(10 each group): asthma group, γ-VitE group control group.In 20 sensitized by exposured to aerosolized ovalbumin challenged same antigen establish model.Rats not treated γ-VitE, rats γ-VitE.Rats normal saline instead ovalbumin.The total cell, acidophilic leukocytes,...