A5009619456- Drug Solubulity and Delivery Systems
- Advancements in Transdermal Drug Delivery
- Advanced Drug Delivery Systems
- Protein purification and stability
- Skin Protection and Aging
- Crystallization and Solubility Studies
- Surfactants and Colloidal Systems
- Bee Products Chemical Analysis
- Microencapsulation and Drying Processes
- Analytical Methods in Pharmaceuticals
- Contact Dermatitis and Allergies
- Analytical Chemistry and Chromatography
- Dermatology and Skin Diseases
- Nanoparticle-Based Drug Delivery
- Electrospun Nanofibers in Biomedical Applications
- Protein Interaction Studies and Fluorescence Analysis
- Monoclonal and Polyclonal Antibodies Research
- Acne and Rosacea Treatments and Effects
- Polysaccharides Composition and Applications
- Toxin Mechanisms and Immunotoxins
- Electrohydrodynamics and Fluid Dynamics
- Spectroscopy and Chemometric Analyses
- Rheology and Fluid Dynamics Studies
- Pancreatic function and diabetes
- Antioxidant Activity and Oxidative Stress
University of Ljubljana
2016-2025
University of Szeged
2022
University of Novi Sad
2022
Weatherford College
2011-2014
Comparative evaluation of liquid and solid self-microemulsifying drug delivery systems (SMEDDS) as promising approaches for solubility enhancement.The aim this work was to develop, characterize, evaluate a SMEDDS prepared via spray-drying based on Gelucire® 44/14 improve the dissolution rate naproxen.Various oils co-surfactants in combination with were evaluated during excipient selection study, testing, construction (pseudo)ternary diagrams. The selected system further naproxen solubility,...
Context: Despite its promising therapeutic activities, clinical use of resveratrol (RSV) is compromised with unfavorable biopharmaceutical properties, namely low water solubility.Objective: This work deals improving RSV solubility and release rate through incorporation in innovative mixed lipid phase self-microemulsifying drug delivery systems (SMEDDS).Methods: (Pseudo)ternary diagrams were constructed for different oils surfactant mixtures. Selected further evaluated solubility,...
Biofilm-associated diseases such as periodontitis are widespread and challenging to treat which calls for new strategies their effective management. Probiotics represent a promising approach targeted treatment of dysbiosis in biofilm modulation host immune response. In this interdisciplinary study, nanofibers with two autochthonous Bacillus strains 27.3.Z 25.2.M were developed. The isolated from the oral microbiota healthy individuals, genomes sequenced screened genes associated...
Dry eye disease is a multifactorial condition characterized by loss of homeostasis the tear film. Among various treatment approaches, application ophthalmic oil-in-water nanoemulsions with incorporated anti-inflammatory drugs represents one most advanced approaches. However, liquid nature limits their retention time at ocular surface. Transforming into dry form that would disperse rapidly in fluid improve drug The aim this study was to investigate electrospinning as method for preparation...
The objective of this work was to investigate the use nanocrystalline cellulose (NCC) as a drug-delivery excipient for buccal films. Gel-like dispersions were created by blending either gel or powder NCC (gNCC pNCC) with natural polymers (alginate, pectin, chitosan) in water, glycerol serving plasticiser. Ibuprofen (IBU) an active pharmaceutical ingredient (API) dissolved self-microemulsifying drug delivery system (SMEDDS) improve its solubility prior addition gel-like dispersions....