- COVID-19 Clinical Research Studies
- Long-Term Effects of COVID-19
- Respiratory Support and Mechanisms
- SARS-CoV-2 and COVID-19 Research
- Sepsis Diagnosis and Treatment
- Intensive Care Unit Cognitive Disorders
- Family and Patient Care in Intensive Care Units
- COVID-19 and Mental Health
- COVID-19 Impact on Reproduction
- COVID-19 epidemiological studies
- Pulmonary Hypertension Research and Treatments
- Lung Cancer Diagnosis and Treatment
- Global Maternal and Child Health
- Global Cancer Incidence and Screening
- Pneumocystis jirovecii pneumonia detection and treatment
- Diagnosis and treatment of tuberculosis
- Lung Cancer Treatments and Mutations
- Acute Kidney Injury Research
- Medical Imaging and Pathology Studies
- Tuberculosis Research and Epidemiology
- Hereditary Neurological Disorders
- Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
- Peripheral Neuropathies and Disorders
- Viral Infections and Outbreaks Research
- Ultrasound in Clinical Applications
Addis Ababa University
2017-2025
Emory University
2024
Tikur Anbessa Hospital
2023
Debre Berhan University
2023
It is now recognized that many patients have persistent symptoms after recovery from acute COVID-19 infection, an infection caused by the coronavirus SARS-CoV-2. This constellation of known as 'Long COVID' may manifest with a wide range physical and cognitive/psychological symptoms. Few data are available on prevalence, attributes, factors associated Long COVID in Africa. was retrospective review patients' electronic medical records Hallelujah General Hospital (one first private hospitals to...
Uncontrolled asthma negatively impacts patients, families, and the community. The level of symptom control among asthmatics in Ethiopia has not been well studied. We investigated risk factors for poor clinic patients seen largest public hospital Ethiopia. In this cross-sectional study, we studied all 182 consecutive subjects with a physician diagnosis who were chest at Tikur Anbessa Specialized Hospital between July December 2015. Of subjects, 68.1% female. mean age was 52 ± 12 years median...
Abstract Guillain–Barré syndrome (GBS) is an acute autoimmune polyneuropathy with substantial geographic variations in demography, antecedent events, clinical manifestations, electrophysiological sub-types, diagnostic findings, treatment modalities, and prognostic indicators. However, there limited contemporary data on GBS patient profiles factors from low-resource settings like Ethiopia. The objective of this study to investigate the profile, associated mortality, hospital outcomes among...
Data from much of Africa are still scarce on the clinical characteristics, outcomes treatment, and factors associated with disease severity mortality COVID-19. A cross-sectional study was conducted at Eka Kotebe General Hospital, Ethiopia's first COVID-19 treatment center. All consecutive symptomatic SARS CoV-2 RT-PCR positive individuals, aged 18 older, admitted to hospital between March 13 September 16, 2020, were included. Of total 463 cases, 319 (68.9%) male. The median age 45 years...
Abstract Background Studies have indicated that hospitalized COVID-19 patients benefit from anticoagulation therapy in terms of survival; however, there is an ongoing controversy over the optimum anticoagulant dosage. This study aimed to compare clinical outcomes between who received prophylactic and those therapeutic anticoagulation. Methods A multi-center retrospective cohort was conducted determine impact dosage Ethiopia. The primary outcome measure in-hospital mortality, it assessed...
The COVID-19 pandemic has been linked to chronic pulmonary complications all over the world. Respiratory such as cough, dyspnea, increased respiratory rate, and oxygen support demand are prevalent in recovered patients. These problems long-term have a negative impact on one's quality of life. Patients must be evaluated for potential complications, risk factors found. Some reports around world explain that contribute development these complications. However, best our understanding, no...
Globally, non‐communicable diseases are increasing in people living with HIV. Pulmonary hypertension is a rare disease HIV reported prevalence of <1%. However, data on pulmonary from Africa scarce and non‐existent Ethiopia. This study aimed to examine the severity echocardiographic risk factors associated A total 315 consecutive adult followed at Tikur Anbessa Specialized Hospital Referral Clinic were enrolled June 2018 February 2019. Those established known causes excluded. structured...
COVID-19, the novel coronavirus, has posed a major threat to low- and middle-income countries (LMICs) due inadequate health infrastructure human resources. Ethiopia, low-income country with second largest population in Africa, coordinated strategic response, leveraging existing systems mobilizing public professionals specialist expert physicians for multifaceted, unified government approach adaptive response. Resource limitations, particularly critical care, have still challenges, but...
Lung cancer is the most common cause of deaths worldwide, accounting for 1.8 million each year. Only 20% lung cases are reported to occur in low- and middle-income countries. An estimated 1.5% all Ethiopian cancers involved lung; however, no nationwide registry exists Ethiopia. Thus, accurate data on clinical history, histopathology, molecular characteristics, risk factors not available. The aim this study was describe clinical, radiologic, pathologic including available profiles, at Tikur...
There has been a rise in secondary invasive fungal infections reported COVID-19 patients globally. We report the first published case of associated rhino-orbital-cerebral mucormycosis Africa newly diagnosed diabetic female who presented with ketoacidosis (DKA) and discuss prevalence risk factors co-infection clinical presentation, diagnosis, management COVID-19.A 39 years old patient was admitted to ICU diagnosis severe diabetes mellitus (DM) DKA based on HgbA1c 13.8% positive RT-PCR. The...
Tuberculosis (TB) is an infectious disease that caused by Mycobacterium tuberculosis. Despite TB being a preventable and curable disease, it still remains to be one of the leading causes mortality worldwide continues prevalent. can manifest in multiple systems, but its primary target lungs. Pulmonary present differently depending on patient's immune status comorbidities. One atypical presentation lung mass, which mimic malignancy cause diagnostic delays.In this case series, we report four...
Introduction In low- and middle-income countries (LMICs), the availability of formal point-of-care ultrasound (POCUS) training remains limited, there is limited data on how to train providers in these use POCUS. This study aimed describe a virtual workshop for physicians Ethiopia, with intention serving as model that could guide similar initiatives. Methods The authors developed implemented three-day 2022 Department Medicine at Addis Ababa University Ethiopia. Participants completed...
Acute ischemic stroke has been reported to occur in a significantly higher number of COVID-19 patients as compared healthy controls with variable proposed pathophysiologic mechanisms. To our knowledge, sufficient data regarding this subject is lacking Ethiopia and the African continent at large. In case series, we report clinical characteristics management 5 cases infection acute shed light on diagnostic therapeutic challenges resource-limited setups.This series including collected from...
Abstract Background Coronavirus disease-19 (COVID-19) has dominated global health conversations within a short period of time. It can seem as if the hugely significant burden infectious diseases, including visceral leishmaniasis, are no longer public issue. We discuss in this case clinical and implications COVID-19 Leishmania donovani co-infection. Case presentation An 18 years old male patient from Northwest Ethiopia diagnosed with concomitant leishmaniasis that ended fatal outcome. The...
Objectives: The objectives of the study were to evaluate benefit awake prone positioning in COVID-19 patients hospitalized at Eka Kotebe General Hospital, Addis Ababa, Ethiopia. Materials and Methods: Consecutive with who require supplemental oxygen maintain saturation ≥90% during month October 2020 enrolled. Structured questionnaires employed collect data. Admission was recorded for each patient before after their first proning session. Analysis descriptive comparison statistics done using...
One of the biggest pandemics human race, Coronavirus disease, has reported mortality rates as high 80% for critically ill patients. It killed more than 3.9 million people worldwide with no strongly proven management options to decrease its mortality. gaining interest is fiberoptic bronchoscopy and bronchoalveolar lavage. Our study was conducted assess clinical outcome intubated disease patients that had a lavage done.A consecutive prospective case series critical pneumonia were at Bethzatha...
Evidence on the interplay between HIV and COVID-19 is not entirely consistent. A retrospective cohort study was conducted medical records of patients who had a positive RT-PCR for were admitted to Eka Kotebe General Hospital March 2020 October 2021. total 427 patients, including 108 people living with HIV/AIDS (PLWH) 319 without HIV/AIDS, included in study. The median age PLWH 49.5 years (interquartile range 40–59 years) 48 32–65 years), respectively. Of these 258 (60.4%) male 169 (39.6%)...
Abstract Background: The COVID-19 pandemic has been linked to chronic pulmonary complications all over the world. Respiratory such as cough, dyspnea, increased respiratory rate, and oxygen support demand are prevalent in recovered patients. These problems long-term have a negative impact on one's quality of life. Patients must be evaluated for potential complications, risk factors found. Some reports around world explain that contribute development these complications. However, best our...