Qian Guan

ORCID: 0000-0001-8298-9470
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Research Areas
  • Gut microbiota and health
  • Pharmacological Effects of Natural Compounds
  • Inflammasome and immune disorders
  • Nerve injury and regeneration
  • Acupuncture Treatment Research Studies
  • Fungal Biology and Applications
  • Cell Adhesion Molecules Research
  • Tea Polyphenols and Effects
  • Synthetic Organic Chemistry Methods
  • Exercise and Physiological Responses
  • Inflammatory mediators and NSAID effects
  • Ubiquitin and proteasome pathways
  • Immune Response and Inflammation
  • Biological and pharmacological studies of plants
  • Gastrointestinal motility and disorders
  • Plant-based Medicinal Research
  • Inflammatory Bowel Disease
  • Ginseng Biological Effects and Applications
  • Plant Pathogens and Fungal Diseases
  • Pain Mechanisms and Treatments
  • Muscle Physiology and Disorders
  • Polydiacetylene-based materials and applications
  • Botulinum Toxin and Related Neurological Disorders
  • Atherosclerosis and Cardiovascular Diseases
  • Thermal Regulation in Medicine

Beijing University of Chinese Medicine
2021-2023

Tuina can effectively alleviate ulcerative colitis-related symptoms, but the mechanism of action is unknown. The purpose this research to explore potential pathways for treatment tuina through gut microbiota and proteomics techniques. Thirty-two male BALB/c mice were divided into four groups, control, model, mesalazine, groups. colitis model was established by freely drinking a 3% dextran sulphate sodium solution 7 days. mesalazine group group, respectively, received days treatment....

10.3389/fmicb.2022.976239 article EN cc-by Frontiers in Microbiology 2022-11-29

ObjectiveTo investigate the mechanism of six-method massage antipyretic process (SMAP) and its influence on body's metabolic state.MethodsThe random number table method was used to divide 24 New Zealand 2-month-old rabbits with qualified basal body temperature into a control group, model group (n = 8 per group). The groups were injected 0.5 μg/ml lipopolysaccharide (1 ml/kg) auricular vein, same amount normal saline at temperature. One hour after modelling, given SMAP (opening Tianmen,...

10.1016/j.heliyon.2023.e23313 article EN cc-by-nc-nd Heliyon 2023-12-04

Previous studies have proved and investigated the mechanism of analgesic effect tuina treatment on neuropathic pain. The purpose this study was to analyze changes in gene expression dorsal root ganglia (DRG) spinal horn (SDH) after 1-time intervention investigate immediate by tuina. An improvement nociceptive behavior minor chronic constriction injury (CCI) rats observed. more effective amelioration thermal hyperalgesia, but no were found ultrastructure DRG SDH. Sixty-five differentially...

10.3389/fnins.2022.1007432 article EN cc-by Frontiers in Neuroscience 2022-10-04

To investigate the changes in hypothalamic metabolites of lipopolysaccharide (LPS) febrile young rabbits after treatment with pediatric tuina. A total 30 were randomly assigned into three groups: normal group, model and tuina group. Both group injected intravenously LPS. "Six antipyretic manipulations" (pushing Tianmen, pushing Kangong, kneading Taiyang, Erhougaogu, clearing Tianheshui, Jizhu) administered 1 h LPS injection The rectal temperatures monitored during experiment to explore...

10.1016/j.jtcms.2022.03.006 article EN cc-by-nc-nd Journal of Traditional Chinese Medical Sciences 2022-04-01

External therapy, which has been used for millennia to treat disease, now become the newest member of complementary and alternative therapies. A growing number clinical studies animal experiments have shown that external therapy exerts a positive effect on intestinal flora. In this paper, we review research related various systemic diseases focus changes in We found are dominated by acupuncture tuina, primarily aimed at treatment digestive neurological diseases. However, deeper mechanism...

10.1016/j.jtcms.2022.11.002 article EN cc-by-nc-nd Journal of Traditional Chinese Medical Sciences 2022-12-01
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