A5041900833- Innovations in Medical Education
- Maternal Mental Health During Pregnancy and Postpartum
- Clinical Reasoning and Diagnostic Skills
- Medication Adherence and Compliance
- Orthopedic Infections and Treatments
- Voice and Speech Disorders
- Dysphagia Assessment and Management
- Digital Mental Health Interventions
- Total Knee Arthroplasty Outcomes
- Orthopaedic implants and arthroplasty
- Heart Failure Treatment and Management
- Sleep and related disorders
- Prenatal Substance Exposure Effects
- Pharmaceutical Practices and Patient Outcomes
- Health Literacy and Information Accessibility
- Diabetes Treatment and Management
- Interprofessional Education and Collaboration
- Mental Health Research Topics
- Air Quality and Health Impacts
- Patient-Provider Communication in Healthcare
- Cardiac Health and Mental Health
- Sleep and Wakefulness Research
- Opioid Use Disorder Treatment
- Platelet Disorders and Treatments
- Clinical Nutrition and Gastroenterology
University of Pittsburgh
2016-2025
University of Pittsburgh Medical Center
2016-2025
General Department of Preventive Medicine
2022
Pittsburg State University
2022
UPMC Montefiore
2019-2021
Carnegie Mellon University
2017-2019
Southern California Clinical and Translational Science Institute
2019
University of Toledo
2018
Magee-Womens Research Institute
2016
Abstract Background We studied humoral responses after coronavirus disease 2019 (COVID-19) vaccination across varying causes of immunodeficiency. Methods Prospective study fully vaccinated immunocompromised adults (solid organ transplant [SOT], hematologic malignancy, solid cancers, autoimmune conditions, human immunodeficiency virus [HIV]) versus nonimmunocompromised healthcare workers (HCWs). The primary outcome was the proportion with a reactive test (seropositive) for immunoglobulin G to...
<h3>Importance</h3> Collaborative care for depression and anxiety is superior to usual from primary physicians these conditions; however, challenges limit its provision in routine practice at scale. Advances technology may overcome barriers but have yet be tested. <h3>Objective</h3> To examine the effectiveness of combining an internet support group (ISG) with online computerized cognitive behavioral therapy (CCBT) provided via a collaborative program treating vs CCBT alone whether providing...
is the major organism responsible for surgical implant infections. Antimicrobial treatment of these infections often fails, leading to expensive intervention and increased risk mortality patient. The challenge in treating associated with high tolerance
This cross-sectional study assesses drug coverage, formulary restrictions, median retail prices, and annual out-of-pocket costs associated with commonly used insulin products across Medicare Part D plans.
To test the effect of duration medication for opioid use disorder (MOUD) during pregnancy on maternal, perinatal and neonatal outcomes.Retrospective cohort analysis claims, encounter pharmacy data.Pennsylvania, USA.We analyzed 13 320 pregnancies among 10 741 women with aged 15-44 years enrolled in Pennsylvania Medicaid between 2009 2017.We examined five outcomes 12 weeks postpartum: (1) overdose, (2) postpartum MOUD continuation, (3) preterm birth (< 37 gestation), (4) term low weight 2500 g...
Importance The latest guidelines continue to recommend sodium-glucose cotransporter 2 (SGLT2) inhibitors and glucagon-like peptide-1 receptor agonists (GLP-1 RAs) for patients with type diabetes (T2D) established cardiovascular disease (CVD). Despite this, overall use of these drug classes has been suboptimal. Objective To assess the association high out-of-pocket (OOP) costs initiation an SGLT2 inhibitor or GLP-1 RA among adults T2D CVD who are treated metformin-treated. Design, Setting,...
Importance Drug shortages are a chronic and worsening issue that compromises patient safety. Despite the destabilizing impact of COVID-19 pandemic on pharmaceutical production, it remains unclear whether issues affecting drug supply chain were more likely to result in meaningful during pandemic. Objective To estimate proportion reports associated with overall Design, Setting, Participants This longitudinal cross-sectional study used data from IQVIA Multinational Integrated Data Analysis...
ABSTRACT Background Despite the existence of institutional protocols, liver transplant centers often have variability in early immunosuppression practices. We aimed to measure within‐center after pediatric (LT) and examine its association with one‐year outcomes. Methods analyzed LTs from 2013 2018 United Network for Organ Sharing registry, data aggregated by center. categorized induction regimen as corticosteroids only vs. T‐cell depleting antibody non‐T‐cell antibody. Primary exposures were...
Importance Neonatal short bowel syndrome with intestinal failure is rare, and observational studies are limited to small cohorts. Health disparities exist in long-term management little known about the initial hospitalization. Objective To identify children neonatal determine whether race, ethnicity, neighborhood opportunity associated length of stay during their hospitalizations. Design, Setting, Participants This cross-sectional study was conducted between 2004 2020, validation analysis...
Total knee arthroplasty (TKA) periprosthetic joint infection (PJI) can be managed with debridement, antibiotic therapy, and implant retention (DAIR). Oral antibiotics used after DAIR for an extended time period to improve outcomes. The objective of this study was compare failure rates adverse events between initial course intravenous therapy the addition treatment oral antibiotics.A multicenter observational patients diagnosed a TKA PJI who underwent performed. primary outcome interest rate...
Objectives/Hypothesis The Voice Handicap Index‐10 (VHI‐10) is commonly used to measure patients' perception of vocal handicap. Clinical consensus has previously defined clinically meaningful improvement as a decrease ≥5. This study determines the minimal important difference (MCID) for VHI‐10 in patients with unilateral fold paralysis (UVFP) using anchor‐based methodology. Study Design Prospective cohort questionnaire analysis. Methods Two hundred eighty‐one UVFP completed on two consecutive...
Depression is often comorbid in patients with heart failure (HF) and associated worse clinical outcomes. However, depression generally goes unrecognized untreated this population.To determine whether a blended collaborative care program for treating both HF can improve outcomes more than only physicians' usual (UC).This 3-arm, single-blind, randomized effectiveness trial recruited 756 participants reduced left ventricular ejection fraction (<45%) from 8 university-based community hospitals...
Summary While insomnia is a well‐established risk factor for the initial onset, recurrence or relapse of affective disorders, specific characteristics that confer remain unclear. Patients with an evening chronotype may be one particularly high‐risk group, perhaps due to alterations in positive affect and its related circuitry. We explored this possibility by comparing diurnal patterns activity affect‐related brain regions morning‐ evening‐types insomnia. assessed variation via relative...
Evening chronotype, a correlate of delayed circadian rhythms, is associated with depression. Altered positive affect (PA) rhythms may mediate the association between evening chronotype and depression severity. Consequently, better understanding relationship PA aid in etiology Recent studies have found that individuals show blunted although these are relatively limited sample size, representativeness number daily measures. Further, published not included how sleep timing changes on workday...
Pregnant women report disturbed sleep beginning in early pregnancy. Among nonpregnant populations, exercise has been associated with improved sleep; however, research pregnant samples equivocal. We examined whether varying degrees of were better nocturnal among during gestation.172 women.Self-reported and objective collected gestation: T1 (10-12 weeks), T2 (14-16 T3 (18-20 weeks) from 172 women. Exercise was categorized into three time-varying groups: 0 metabolic equivalent minutes per week...
Abstract Purpose Teams play a central role in the implementation of new practices settings providing team-based care. However, science literature has paid little attention to potentially important team-level constructs. Aspects teamwork, including team interdependence, functioning, and performance, may affect processes outcomes. This cross-sectional study tests associations between teamwork antecedents outcomes statewide initiative implement standardized mental health screening/referral...
Importance Youths with type 2 diabetes are at higher risk for complications compared peers 1 diabetes, though few studies have evaluated differences in access to specialty care. Objective To compare claims specialists youths vs and the association between specialist multidisciplinary acute care utilization. Design, Setting, Participants This cross-sectional study used Optum Clinformatics Data Mart commercial claims. Individuals included were younger than 19 years or as determined by a...
Purpose Shared decision making (SDM) is a core competency in health policy and guidelines. Most U.S. internal medicine residencies lack an SDM education curriculum. A standardized patient (SP)-based curriculum teaching key concepts skills of was developed. Method This consisted innovative seven-step model skills-focused SP case, integrated into the ambulatory rotation for senior residents at University Pittsburgh Medical Center 2015. Evaluation pre/postcurriculum surveys assessing residents’...