Jingang Gu

ORCID: 0000-0001-8321-9400
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About
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Research Areas
  • Enzyme Production and Characterization
  • Genomics and Phylogenetic Studies
  • Microbial Community Ecology and Physiology
  • Biofuel production and bioconversion
  • Studies on Chitinases and Chitosanases
  • Pharmacological Effects of Natural Compounds
  • Berberine and alkaloids research
  • Fungal Biology and Applications
  • Analytical chemistry methods development
  • Ruminant Nutrition and Digestive Physiology
  • Traditional Chinese Medicine Analysis
  • Pharmaceutical and Antibiotic Environmental Impacts
  • Antioxidants, Aging, Portulaca oleracea
  • Bacteriophages and microbial interactions
  • Plant-based Medicinal Research
  • Innovative Microfluidic and Catalytic Techniques Innovation
  • Hydrocarbon exploration and reservoir analysis
  • Pesticide and Herbicide Environmental Studies
  • Microbial Metabolites in Food Biotechnology
  • Carbohydrate Chemistry and Synthesis
  • Paraquat toxicity studies and treatments
  • Plant-Microbe Interactions and Immunity
  • Gut microbiota and health
  • Chromatography in Natural Products
  • Animal Nutrition and Physiology

Institute of Agricultural Resources and Regional Planning
2013-2025

Chinese Academy of Agricultural Sciences
2013-2025

Ministry of Agriculture and Rural Affairs
2025

Nanjing Agricultural University
2014

Wuhan University
2011

Ruminants excrete both undigested and excess consumed nitrogen (N) through feces urine, which results in the waste of feed protein environmental pollution. This study aims to screen bacteria identify strains with potential improve utilization rumen. In a tube screening test, when 30 mmol/L ammonium sulfate was added as only source liquid medium, among 115 bacterial belonging Bacillus lactic-acid bacteria, 10 highest growth (OD600nm level) comparison other evaluated were identified, these,...

10.3389/fmicb.2024.1498109 article EN cc-by Frontiers in Microbiology 2025-01-17

The volatile organic compounds (VOCs) in Trichoderma afroharzianum ACCC 33109 have the biological activities of both hydrolytic enzymes and antimicrobial peptides to mitigate attack by phytopathogens spread over long distances soil. However, biosynthesis pathway anti-fungal VOCs has not been elucidated yet. In this study, we identified 15 genes (TaTS1–15) coding for putative terpene synthase with low identities (<79.54%) functionally characterized homologs through genome mining. Upon...

10.3390/catal15040341 article EN Catalysts 2025-04-01

Alkaline lipases with adaptability to low temperatures and strong surfactant tolerance are favorable for application in the detergent industry. In present study, a lipase-encoding gene, TllipA, was cloned from Trichoderma lentiforme ACCC30425 expressed Pichia pastoris GS115. The purified recombinant TlLipA found have optimal activities at 50 °C pH 9.5 retain stable over range of 6.0-10.0 40 below. When using esters different lengths as substrates, showed preference medium length...

10.1186/s13568-018-0618-z article EN cc-by AMB Express 2018-06-05

Berberine (BBR) is an isoquinoline alkaloid, reported to have multiple pharmacological functions. However, its effects against CCl4‑induced oxidative damage remain poorly studied. Therefore, the present study investigated protective action of BBR, and antioxidant mechanisms, liver injury in rats. A total 48 rats were randomly arranged into six groups: Control; model; positive control (PC); BBR low‑dose (BL); middle‑dose (BM); high‑dose (BH). The BL, BM BH animals received (5, 10 15 mg/kg by...

10.3892/mmr.2019.10551 article EN cc-by-nc-nd Molecular Medicine Reports 2019-08-06

We isolated a Gram-stain-negative, pink-pigmented, motile, pleomorphic, extremely halophilic archaeon from the brine-seawater interface of Discovery Deep in Saudi Arabian Red Sea. This strain, designated SB9T, was capable growth within wide range temperatures and salinity, but required MgCl2. Cells lysed distilled water, at 7.0 % (w/v) NaCl cell lysis prevented. The major polar lipids strain SB9T were phosphatidylglycerol, phosphatidylglycerolphosphate methyl ester, sulfated mannosyl...

10.1099/ijsem.0.001559 article EN INTERNATIONAL JOURNAL OF SYSTEMATIC AND EVOLUTIONARY MICROBIOLOGY 2016-10-10

A novel aerobic, non-spore-forming, non-motile, catalase- and oxidase-positive, Gram-stain-negative, coccoid to short-rod-shaped bacterial strain, designated YW11 T , was isolated from soil under long-term application of triazophos. The strain able hydrolyse Strain grew at 15–40 °C (optimum 28 °C), pH 5.0–8.0 7.5) with 0–5.0 % (w/v) NaCl 0.5 %). major respiratory quinone ubiquinone 10 (Q-10) the cellular fatty acids were C 18 : 1 ω7 c 16 0 2-OH . genomic DNA G+C content 69.6±0.5 mol%. polar...

10.1099/ijs.0.057000-0 article EN INTERNATIONAL JOURNAL OF SYSTEMATIC AND EVOLUTIONARY MICROBIOLOGY 2014-01-10

Weaning is a challenging period for piglets, characterized by stress-related growth checks, compromised immunity, and gut dysbiosis. Purslane (Portulaca oleracea L.), known its rich content of antioxidants, has potential as functional feed ingredient. This study investigates the effects feeding fermented purslane (FP) on performance, immune function, intestinal microbiota, metabolic profiles weaned piglets. Forty-eight piglets were randomly divided into two groups, with eight pens in each...

10.3390/microorganisms12071403 article EN cc-by Microorganisms 2024-07-11

Abstract Background Chronic liver diseases can interfere with hepatic metabolism of lipoproteins, apolipoproteins. Hepatitis B virus (HBV) is a major etiological agent causing acute and chronic diseases. Apolipoprotein M (ApoM) high-density lipoprotein (HDL) apolipoprotein exclusively expressed in the parenchyma cells tubular kidney. This study was to determine correlation between HBV infection ApoM expression. Materials methods Serum levels patients healthy individuals were measured by...

10.1186/1476-511x-10-154 article EN cc-by Lipids in Health and Disease 2011-08-29

Carbonized herbal medicine has been used clinically for centuries in China; however, its influence on the bioavailability of compatible medicinal herbs is still unknown.To explore effect a carbonized vivo adsorption and release absorption other active pharmaceutical ingredients compound prescription.The Herba schizonepetae (CHS) to eight components (epiberberine, coptisine, palmatine, berberine, phellodendrine, aesculin, aesculetin, anemoside B4) aqueous extract Pulsatillae Decoction (PDAE)...

10.2174/1389200222666211029145512 article EN Current Drug Metabolism 2021-10-01

Endo-β-N-acetylglucosaminidase is used widely in the glycobiology studies and industries. In this study, a new endo-β-N-acetylglucosaminidase, designated as Endo SA, was cloned from Streptomyces alfalfae ACCC 40021 expressed Escherichia coli BL21 (DE3). The purified recombinant SA exhibited maximum activity at 35 ºC pH 6.0, good thermo/pH stability high specific (1.0×10⁶ U/mg). It displayed deglycosylation towards different protein substrates. These properties make EndoSA potential tool...

10.13345/j.cjb.190474 article EN PubMed 2020-05-25

Abstract Background: For the last few years huge quantity of herb residues are discharged in China, and so far there is not a good solution. The current methods disposal utilization (stacking, incineration, landfill) were only great harmful to ecological environment, but also cause waste medicinal resources. fermentation can further decompose transform active ingredients nutrients residue, technology has application prospect treatment residues. In this study, we investigated applicability...

10.21203/rs.3.rs-80025/v1 preprint EN cc-by Research Square (Research Square) 2020-09-28
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