A5011427533- Asymmetric Synthesis and Catalysis
- Synthesis and Catalytic Reactions
- Sulfur-Based Synthesis Techniques
- Synthesis of β-Lactam Compounds
- Synthesis of Indole Derivatives
- Fluorine in Organic Chemistry
Jilin University
2017-2019
Jilin Medical University
2019
An efficient enantioselective aza-Henry reaction of aryl α-ketoester-derived ketimines has been realized by using bifunctional thiourea–ammonium salt phase-transfer catalysts, which were derived from quinine. A variety N-Ts investigated, and the corresponding products obtained in high to excellent yields (up 99%) with good enantioselectivities >99% ee).
Abstract An efficient diastereo‐ and enantioselective aza‐Henry reaction of β,γ ‐unsaturated nitroalkenes with N‐ Boc amidosulfones has been realized under the catalysis bifunctional chiral phase‐transfer catalysts bearing multiple H‐bonding donors, which was derived from cinchona alkaloids. This asymmetric catalytic protocol is suitable for a wide range substrates, give corresponding products in high to excellent yields (up 99%) enantioselectivities >99 : 1 dr, up >99% ee). Density...
An efficient enantioselective vinylogous Mannich reaction of <italic>N</italic>-Boc aminosulfones with noncyclic α,α-dicyanoolefins has been realized using an extraordinary bifunctional thiourea–ammonium salt phase transfer catalyst derived from quinine.