- Essential Oils and Antimicrobial Activity
- Phytochemistry and Biological Activities
- Natural Antidiabetic Agents Studies
- Natural product bioactivities and synthesis
- Moringa oleifera research and applications
- Advanced Drug Delivery Systems
- Ovarian cancer diagnosis and treatment
- Phytochemical compounds biological activities
- Seaweed-derived Bioactive Compounds
- Hepatocellular Carcinoma Treatment and Prognosis
- Pharmacological Effects of Medicinal Plants
- HIV Research and Treatment
- Drug-Induced Hepatotoxicity and Protection
- Phytochemistry and biological activity of medicinal plants
- Genomics, phytochemicals, and oxidative stress
- Multiple and Secondary Primary Cancers
- Phytochemicals and Antioxidant Activities
- Traditional Chinese Medicine Analysis
- Phytochemistry and Bioactive Compounds
Tanta University
2024-2025
National Research Centre
2016-2023
Hyperglycaemia plays an important role in the development of non-alcoholic fatty liver disease, which is a common complication diabetics.The present study aimed to investigate chemical composition and efficacy Commiphora opobalsamum stem bark butanol fraction ameliorating injury associated with diabetes induced by streptozotocin (STZ) rats.The was applied high-performance liquid chromatography-mass spectrometry (HPLC/MSn) identify most bioactive metabolites. Diabetes single intraperitoneal...
Astragalus L. species were reported for their important biological activities and they used in the treatment of several diseases. sieberi DC. is a wild plant belonging to family Fabaceae growing Egyptian deserts. The was subjected extraction by 70% methanol give total aqueous extract which fractionated organic solvent three fractions; petroleum ether (Pet.Ether), ethyl acetate (EtOAc) (MeOH). These fractions screened vitro cytotoxic activity using colon (HCT-116) breast (MCF-7) carcinoma...
T WENTY ONE compounds (twelve flavonoids, four benzoylglucarate isomers, two phenolic acids, glucosinolates, and one saccharide) were identified from the B. senegalensis aqueous methanolic extract using LC-ESI-MS technique.Among compounds, quercetin-O-sinapoylglucoside-O-glucoside (13) quercetin-di-O-benzoyl glucoside ( 16) are newly natural products.B. showed strong inhibitory effect against H5N1 viruses moderate antitumor activity three carcinoma cell lines.
Cisplatin (cis) is a chemotherapeutic drug used for cancer treatment. The current study intended to investigate the anticancer effect of cis against Ehrlich Ascites Carcinoma (EAC) via suppressing expression Akt gene with assessment its oxidative stress on kidney tissue. involved forty female mice which were divided into 4 groups: Group I (Negative control), injected isotonic saline solution intraperitoneally (i.p). II (Cis), (i.p) (10 mg/kg) 3times/week. III (EAC), 0.5x106 EAC...
Asphodelus species are among many plants used in traditional medicine, they by native peoples for various pathologies.Asphodelus aestivus Brot. is one of which considered an important wild medicinal plant growing mainly at Mediterranean region.The present study aims to investigate the chemical constituents and cytotoxic evaluation A. flowers.Petroleum ether extract was analyzed GC/MS assay revealed characterization twenty nine compounds, representing 93.13% total extract.Also,...