A5020188891- Phytochemistry and Biological Activities
- Natural product bioactivities and synthesis
- Phytochemicals and Antioxidant Activities
- Essential Oils and Antimicrobial Activity
- Natural Antidiabetic Agents Studies
- Phytochemistry and Bioactive Compounds
- Traditional and Medicinal Uses of Annonaceae
- Sesquiterpenes and Asteraceae Studies
- Traditional Chinese Medicine Analysis
- Phytochemical Studies and Bioactivities
- Phytochemical compounds biological activities
- Plant biochemistry and biosynthesis
- Phytochemistry and biological activity of medicinal plants
- Plant Ecology and Taxonomy Studies
- Pharmacological Effects of Medicinal Plants
- Drug-Induced Hepatotoxicity and Protection
- Medicinal Plants and Neuroprotection
- Cholinesterase and Neurodegenerative Diseases
- Plant Diversity and Evolution
- Ethnobotanical and Medicinal Plants Studies
- Genomics, phytochemicals, and oxidative stress
- Phytochemistry and Bioactivity Studies
- Piperaceae Chemical and Biological Studies
- Medicinal Plants and Bioactive Compounds
- Bamboo properties and applications
National Research Centre
2016-2025
Cairo University
2016
National Water Research Center
2013
Flavonoids are important secondary plant metabolites that have been studied for a long time their therapeutic potential in inflammatory diseases because of cytokine-modulatory effects. Five flavonoid aglycones were isolated and identified from the hydrolyzed aqueous methanol extracts Anastatica hierochuntica L., Citrus reticulata Blanco, Kickxia aegyptiaca (L.) Nabelek. They as taxifolin (1), pectolinarigenin (2), tangeretin (3), gardenin B (4), hispidulin (5). These structures elucidated...
Determination of antioxidant and antimutagenic activities Phlomis armeniaca Mentha pulegiumOnder YUMRUTAS, Saadet D. SAYGIDEGER
Raphanus raphanistrum L. is an edible flowering plant that belongs to the Brassicaceae family and also known as wild radish. Recently, it was reported a sustainable source of bioactive compounds nutrients. For comprehensive metabolites profiling R. whole plant, three types extracts; aqueous ethanol (AEE), dichloromethane (DCME), defatted (DAEE), were prepared. DCME investigated by GC/MS analysis led characterization twenty-nine from unsaponifiable fraction fourteen saponifiable one....
Two new flavonoid compounds were isolated from Astragalus bombycinus Boiss. and identified as quercetin-3,7-di-O-β-glucopyranoside 4'-O-α-rhamnopyranoside 5,2',4'-trihydroxy-flavone-8-C-α-arabinopyranoside-7-O-β-glucopyranoside. In addition, apigenin, apigenin-7-O-β-glucopyranoside, apigenin 7-O-gentobioside, luteolin, luteolin-7-O-β-glucopyranoside, quercetin-3,7-di-O-β-glucopyranoside, quercetin-3-O-β-glucopyranoside-7-O-α-rhamnopyranoside daidzein also identified. The structure...
One new naturally isoflavone compound, 5,7,2',3',4' penta hydroxyl isoflavone-4'-O-β-glucopyranoside (1) was isolated from the aqueous methanol extract (AME) of Pulicaria undulata subsp. undulata, together with seven known compounds: kaempferol (2), 3-O-β-glucoside (3), quercetin (4), (5), 3-O-β-galactoside (6), 3,7-di OCH3 (7), and caffeic acid (8). Their structures were established through chemical (acid hydrolysis) spectral analysis (UV, NMR, ESIM). The AME some compounds evaluated as...
Although inflammation is a beneficial response to harmful triggers, the associated diseases develop potential for death-threatening conditions. Citrus species are valuable sources of chemical compounds with diverse structural properties that could alleviate damaging and reduce serious side effects synthetic drugs. Kumquats smallest trees among citrus family widely distributed in Asia, Europe, North America, little cultivation Africa. The current study aims conduct comprehensive chemical,...
The Red Sea is one of the most biodiverse aquatic ecosystems. Notably, seagrasses possess a crucial ecological significance. Among them are two taxa Halophila stipulacea (Forsk.) Aschers., and Thalassia hemprichii (Ehrenb. ex Solms) Asch., which were formally ranked together with genus Enhalus in three separate families. Nevertheless, they have been recently classified as subfamilies within Hydrocharitaceae. interest this study to explore their metabolic profiles through...
AbstractTwelve compounds were isolated from Chrozophora tinctoria (L.) Raf. They identified as kaempferol, kaempferol 3-O-β-glucopyranoside, 3-O-(6″-α-rhamnopyranosyl)-β-glucopyranoside, quercetin, quercetin apigenin, apigenin 7-O-β-glucopyranoside, acacetin, gallic acid, methyl gallate and β-sitosterol-3-O-β-glucopyranoside. Their structures elucidated by chemical spectral methods. Furthermore, chemosystematics of the is briefly discussed. It was indicated that C. only species has...
Abstract Trifolium resupinatum L., Fabaceae, aqueous methanol leaf extract was selected to mitigate some obesity-associated risk factors validate the possibility of further developing herbal drugs. Chromatography and spectrophotometric techniques verified 14 phenolics, five which were first isolated from plant identified as 6''- O -acetyl ononin, genistin, daidzin, sissotrin, astragalin. Further phytochemical characterization performed via liquid chromatography-electrospray ionization-mass...
Thirteen flavonoid compounds were isolated for the first time from aerial parts of Erucaria hispanica (L.) Druce growing in Egypt. Their structures established on basis detailed chromatographic and spectroscopic techniques (UV, 1D 2D NMR ESIMS). The cytotoxic activity methanol extract as well some against four human carcinoma cell lines; breast (MCF7), liver (HEPG2), cervix (HELA) colon (HCT116) evaluated.
The genus Sterculia is represented by 200 species which are widespread mainly in tropical and subtropical regions. Some of the classified under different genera based on special morphological features. These Pterygota Schott & Endl., Firmiana Marsili, Brachychiton Hildegardia Pterocymbium R. Br. Scaphium Endl. related contain flavonoids, whereas terpenoids, phenolic acids, phenylpropanoids, alkaloids, other types compounds including sugars, fatty lignans lignins less distribution. biological...
A new flavone glycoside tricin 7-O-β-glucopyranoside-2″-sulphate sodium salt along with 14 known flavonoid compounds were isolated and identified from the aqueous methanol extract of Livistona australis leaves. Their structures established on basis extensive NMR (1H, 13C, HSQC H-H COSY) ESIMS data. Antioxidant cytotoxicity properties leaves as well compound investigated.
Centaurea is a genus compromising over 250 herbaceous flowering species and used traditionally to treat several ailments. Among the Egyptian species, C. lipii was reported be cytotoxic against multidrug-resistant cancer cells. In this context, we aimed explore metabolome of compare it other members in pursuance identifying its bioactive principles. An LC-MS/MS analysis approach synchronized with feature-based molecular networks adopted offer holistic overview diversity species. The studied...
LC-ESI-MS profile, antioxidant activity and cytotoxic screening of Oligomeris linifolia (Vahl) Macbr. (Resedaceae)Ali M. El-Hagrassy, Ahmed Elkhateeb, Sameh R. Hussein, El-Sayed S. Abdel-Hameed, Mona Marzouk
Astragalus L. species were reported for their important biological activities and they used in the treatment of several diseases. sieberi DC. is a wild plant belonging to family Fabaceae growing Egyptian deserts. The was subjected extraction by 70% methanol give total aqueous extract which fractionated organic solvent three fractions; petroleum ether (Pet.Ether), ethyl acetate (EtOAc) (MeOH). These fractions screened vitro cytotoxic activity using colon (HCT-116) breast (MCF-7) carcinoma...