Shahira M. Ezzat

ORCID: 0000-0003-2232-7357
Publications
Citations
Views
---
Saved
---
About
Contact & Profiles
Research Areas
  • Phytochemicals and Antioxidant Activities
  • Phytochemistry and Biological Activities
  • Essential Oils and Antimicrobial Activity
  • Natural product bioactivities and synthesis
  • Natural Antidiabetic Agents Studies
  • Drug-Induced Hepatotoxicity and Protection
  • Pharmacological Effects of Natural Compounds
  • Phytochemical Studies and Bioactivities
  • Plant biochemistry and biosynthesis
  • Ethnobotanical and Medicinal Plants Studies
  • Phytochemistry and biological activity of medicinal plants
  • Metabolomics and Mass Spectrometry Studies
  • Sesquiterpenes and Asteraceae Studies
  • Phytochemistry and Bioactive Compounds
  • Phytochemical compounds biological activities
  • Advances in Cucurbitaceae Research
  • Liver Disease Diagnosis and Treatment
  • Medicinal Plants and Neuroprotection
  • Hibiscus Plant Research Studies
  • Phytochemistry and biological activities of Ficus species
  • Potato Plant Research
  • Phytoestrogen effects and research
  • Phytochemicals and Medicinal Plants
  • Liver physiology and pathology
  • Fungal Biology and Applications

Cairo University
2016-2025

October University of Modern Sciences and Arts
2017-2025

Bridge University
2022

British University in Egypt
2022

IBM (Egypt)
2020

Pharmac
2019

National Organization for Drug Control and Research
2016

Universität Ulm
2016

Desert Research Center
2003

Menoufia University
2003

Quercetin (Que) and its derivatives are naturally occurring phytochemicals with promising bioactive effects. The antidiabetic, anti-inflammatory, antioxidant, antimicrobial, anti-Alzheimer's, antiarthritic, cardiovascular, wound-healing effects of Que have been extensively investigated, as well anticancer activity against different cancer cell lines has recently reported. found predominantly in the Western diet, people might benefit from their protective effect just by taking them via diets...

10.1021/acsomega.0c01818 article EN cc-by ACS Omega 2020-05-14

Abstract Hydrogen has emerged as a promising energy source for cleaner and more sustainable future due to its clean-burning nature, versatility, high content. Moreover, hydrogen is an carrier with the potential replace fossil fuels primary of in various industries. In this review article, we explore part global mix current state development. The majority production currently occurs through steam methane reforming, which produces significant greenhouse gas emissions limits clean source....

10.1007/s10668-024-04892-z article EN cc-by Environment Development and Sustainability 2024-05-02

Abstract Hepatocellular carcinoma (HCC) is progressively increasing tumor with lack of accurate prognosis and inadequate systemic treatment approaches. Solanum sp. (such as melongena ) a folk herb which reported to possess anticancer properties. In continuity for our interest in pursuing the activity compounds isolated from fruit peels , HPLC profiling ESI-MS assessment methanolic extract evidenced presence bioactive glycoalkaloids (solasonine, solasodine solamargine). These were isolated,...

10.1038/s41598-018-36089-6 article EN cc-by Scientific Reports 2019-02-11

The immune system is a potent army that defends our body against various infections and diseases through innate adaptive immunity. Herbal medicine one of the essential sources for enhancing immunity because affordability, availability, minor side effects, consumers' preferences. Hazelnuts, walnuts, almonds, peanuts are among most widespread edible nuts rich in phenolics, fats, fibers, vitamins, proteins, minerals. potential nut shells phytoremediation has attracted increasing attention as...

10.3390/antiox11030462 article EN cc-by Antioxidants 2022-02-25

Moringa peregrina is a wild plant that grown in the eastern desert mountains Egypt. Although, this native to Egypt, no details studies were traced on its chemical composition and biological activity.The different fractions of ethanolic extract dried aerial parts plants subjected fractionation purification various silica sephadex columns for isolation major compounds which tested there anticancer activity. The aqueous as well antihyperglycemic effect Streptozitocin-induced diabetes...

10.4103/0973-1296.80667 article EN Pharmacognosy Magazine 2011-01-01

Genus Aloe, Xanthorrhoeaceae, is well distributed all over Egypt, and many species have been used as medicinal plants; mainly reported to prevent cardiovascular diseases, cancer diabetes. This study attempts analyze the secondary metabolites in methanol extract of leaves eight Aloe species; A. vera (L.) Burm. f., arborescens Mill., eru Berger, grandidentata Salm-Dyck, perfoliata L., brevifolia saponaria Haw. ferox Mill. growing Egypt. For this aim HPLC–DAD–MS/MS negative ion mode was used....

10.1016/j.bjp.2016.01.009 article EN cc-by-nc-nd Revista Brasileira de Farmacognosia 2016-04-02

Solidago virgaurea L. (Asteraceae) is traditionally used as an anti-inflammatory for the treatment of various symptoms including cystitis. However, little known concerning constituents responsible this activity and mechanism their action.To assess phenolic-rich fraction S. aerial parts in rats, isolate major compounds present.An HPLC method was developed analysis (EtFr). The vivo EtFr four isolated (at 25 50 mg/kg) were assessed adult male rats using carrageenan-induced rat paw oedema model....

10.1080/13880209.2016.1190381 article EN Pharmaceutical Biology 2016-06-01

The objective of our study is to highlight the therapeutic effect and mechanism action by which purified Flaxseed hydrolysate (PFH) a lignan rich fraction exerts its anticancer activity on human breast cancer cell line (T47D) in mice bearing tumor. HPLC analysis PFH six flaxseed cultivars had shown that cultivar Giza 9 (PFH-G9) contains highest concentration SDG (81.64 mg/g). vitro cytotoxic potentiality PFH's was screened against panel lines. -G9 showed most significant ER-receptor positive...

10.1038/s41598-017-18944-0 article EN cc-by Scientific Reports 2018-01-05

Phyllanthus niruri L. is a widespread tropical plant which used in Ayurvedic system for liver and kidney ailments. The present study aims at specifying the most active hepatoprotective extract of P. applying bio-guided protocol to identify compounds responsible this effect. aerial parts were extracted separately with water, 50%, 70% 80% ethanol. cytoprotective activity extracts was evaluated against CCl4-induced hepatotoxicity clone-9 Hepg2 cells. Bioassay-guided fractionation aqueous (AE)...

10.1371/journal.pone.0226185 article EN cc-by PLoS ONE 2020-01-15

Estrogen signaling is crucial for breast cancer initiation and progression. Endocrine-based therapies comprising estrogen receptor (ER) modulators aromatase inhibitors remain the mainstay of treatment. This study aimed at investigating antitumor potential most potent compounds in citrus peels on by exploring their anti-estrogenic anti-aromatase activities. The ethanolic extract different varieties along with eight isolated flavonoids were screened against estrogen-dependent cell lines...

10.1038/s41598-021-86599-z article EN cc-by Scientific Reports 2021-03-29

Aging of the skin is a complicated bioprocess that affected by constant exposure to ultraviolet irradiation. The application herbal-based anti-aging creams still best choice for treatment. In present study, Citrus sinensis L. fruit peels ethanolic extract (CSPE) was formulated into lipid nanoparticles (LNPs) cream. Eight different formulations CSEP-LNPs were prepared and optimized using 23 full factorial designs. vivo antiaging effect formula tested in Swiss albino mice where photo-aging...

10.1016/j.biopha.2021.111537 article EN Biomedicine & Pharmacotherapy 2021-04-05
Coming Soon ...