About
Contact & Profiles
A5064032865
Research Areas
- Microtubule and mitosis dynamics
- Endoplasmic Reticulum Stress and Disease
- Genetic and Kidney Cyst Diseases
- Mitochondrial Function and Pathology
- DNA Repair Mechanisms
McGill University
2019-2021
10.1016/j.str.2021.01.001
article
EN
publisher-specific-oa
Structure
2021-02-01
Abstract In human, the Parkin Co-Regulated Gene (PACRG) shares a bidirectional promoter with Parkin, gene involved in Parkinson’s disease, mitochondrial quality control and inflammation. The PACRG protein is essential to formation of inner junction between doublet microtubules axoneme, structure found flagella cilia. interacts tubulin as well meiosis expressed 1 (MEIG1) protein, which for spermiogenesis mice. However, 3D human unknown. Here, we report crystal C-terminal domain complex MEIG1...
10.1101/783373
preprint
EN
cc-by-nc-nd
bioRxiv (Cold Spring Harbor Laboratory)
2019-09-27
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