A5049753433- Schizophrenia research and treatment
- Eating Disorders and Behaviors
- Mental Health and Psychiatry
- Mental Health Research Topics
- Bipolar Disorder and Treatment
- Obsessive-Compulsive Spectrum Disorders
- Mental Health Treatment and Access
- Obesity, Physical Activity, Diet
- Treatment of Major Depression
- Psychiatric care and mental health services
- Sexuality, Behavior, and Technology
- Obesity and Health Practices
- Attention Deficit Hyperactivity Disorder
- Body Image and Dysmorphia Studies
- MRI in cancer diagnosis
- Gender, Feminism, and Media
- Medical Imaging Techniques and Applications
- Health and Well-being Studies
- Genetics and Physical Performance
- Transcranial Magnetic Stimulation Studies
- Neural and Behavioral Psychology Studies
- Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes
- Child Nutrition and Feeding Issues
- Psychiatry, Mental Health, Neuroscience
- Epilepsy research and treatment
Centro San Giovanni di Dio Fatebenefratelli
2025
Istituti di Ricovero e Cura a Carattere Scientifico
2025
Azienda Usl Toscana Centro
2023-2024
University of Florence
2018-2023
Azienda Ospedaliero-Universitaria Careggi
2019-2022
Agenzia Regionale di Sanità della Toscana
2021
Regione Toscana
2021
Abstract Objective The study aimed to investigate the complex relationship between eating disorder (ED) specific psychopathology, emotion dysregulation, and their longitudinal variations in patients with anorexia nervosa (AN) treated a multidisciplinary approach including enhanced cognitive‐behavior therapy (CBT‐E), provide an integrated model which includes childhood trauma as predictor of worse treatment outcomes. Method In total, 120 female AN were evaluated at admission (T0), 105...
Schizophrenia Spectrum Disorders (SSD) display notable sex differences: males have an earlier onset and more severe negative symptoms, while females exhibit affective better verbal abilities, a favourable prognosis. Despite extensive research, areas such as time perception positivity remain underexplored, machine learning has not yet been adequately utilised. This study aims to address these gaps by examining differences in sample of Italian patients with SSD using data-driven approach. As...
Abstract Background Recovery and human rights promotion for people with Schizophrenia Spectrum Disorders (SSDs) is fundamental to provide good care in Residential Facilities (RFs). However, there a concern about rehabilitation ethos RFs. This study aimed investigate the quality of Italian RFs, life (QoL) experience residents SSD. Methods Fourty-eight RFs were assessed using assessment tool (QuIRC-SA) 161 SSD enrolled. Seventeen provided high intensity (SRP1), 15 medium (SRP2), 16 medium-low...
The present study explored the psychopathological, behavioral, and putative biological underpinnings of dysregulated sexuality in eating disorders (EDs), focusing on role childhood trauma – evaluated with Childhood Trauma Questionnaire (CTQ). comparison between Binge-Purging Restricting patients outlined predominance markers first subgroup. In clinical sample, hypersexuality measured through Hypersexual Behavior Inventory (HBI) was associated severe psychopathology, emotion dysregulation,...
Adolescence represents a critical period for the onset of eating disorders (EDs). The present study aimed to provide prevalence individuals at risk EDs psychopathology in representative population adolescents aged 14-19 and characterize this regarding interpersonal psychological factors.The percentage participants high school was assessed through SCOFF screening questionnaire (cut-off score: 3) total sample (N: 6551) gender-based subgroups different body mass index (BMI) categories. Odds...
Background Cocaine use disorder (CUD) is a global health issue with no effective treatment. Repetitive Transcranial Magnetic Stimulation (rTMS) recently proposed therapy for CUD. Methods We conducted single-center, randomised, sham-controlled, blinded, parallel-group research patients randomly allocated to rTMS (15 Hz) or Sham group (1:1) using computerised block randomisation process. enrolled 62 of 81 CUD in two years. Patients were followed eight weeks after receiving 15 Hz rTMS/sham...
Aberrant salience is the incorrect assignment of salience, significance, or value to different innocuous stimuli that might precede onset psychotic symptoms. The present study aimed perform a preliminary evaluation potentially correlations between Salience Inventory (ASI) score and dimensional categorical diagnostic approaches.168 adult outpatients with current psychiatric diagnosis were consecutively enrolled. Patients evaluated using psychometric scales. ASI was used evaluate aberrant...
Disordered eating and body image concerns are increasingly common among adolescents, possibly representing the underpinning of disorders (EDs). This cross-sectional observational study aimed at investigating relationship between various patterns sports involvement or inactivity, abovementioned psychopathological dimensions.All adolescents attending their 3rd-5th Italian grade in a single high school reported sociodemographic anthropometric data, weekly involvement, filled Eating Disorders...
Abstract Background: To present real-world evidence on the effects of switching from oral to long-acting injectable (LAI) antipsychotic maintenance treatment (AMT) in a sample clinically stable patients with schizophrenia, regard subjective experience treatment, attitude towards drug and quality life. Methods: 50 adult schizophrenic outpatients were recruited. At time enrolment (T0), all under stabilized therapy single second-generation (SGA) switched equivalent regimen formulation same...
This study evaluated the relationship between negative symptoms, daily time use (productive/non-productive activities, PA/NPA), and emotions in schizophrenia-spectrum disorders (SSDs): 618 individuals with SSDs (311 residential care patients [RCPs], 307 outpatients) were surveyed about socio-demographic, clinical (BPRS, BNSS) (paper-and-pencil Time Use Survey completed twice/week) characteristics. Among them 57 RCPs 46 outpatients, matched to 112 healthy controls, also underwent ecological...
Objective Switching to long-acting injectable (LAI) antipsychotic maintenance treatment (AMT) represents a valuable strategy for schizophrenia. In recovery-oriented approach, patient-reported outcomes (PROs) such as perceived disability, subjective well-being, and quality of life cannot be neglected.Methods Forty clinically stable outpatients with schizophrenia treated oral second-generation antipsychotics were enrolled at the time switching equivalent dose LAI. 35 subjects completed this...
Long-acting injectable antipsychotics (LAIs) have been shown to reduce acute episodes of schizophrenia spectrum disorders (SSDs). However, breakthrough relapses are frequent, possibly because underdosing in clinical practice. In this framework, the advantages therapeutic drug monitoring (TDM) may be overlooked. This study explored association low steady-state LAI levels with a higher risk relapse SSDs, despite use licensed posology.Forty-eight clinically stable outpatients SSD underwent...
Given the importance of patients’ subjective experience and attitudes in management severe mental illness, present study evaluated their potential role as predictors future continuation long-acting injectable antipsychotic maintenance treatment (LAI-AMT) clinically stable outpatients with schizophrenia switching from an oral therapy. Retrospective data 59 subjects receiving LAI-AMT for at least 6 months were collected. Patients who continued LAI ( n = 32) compared to those discontinued it...
La riabilitazione in psichiatria assume varie forme a seconda delle esigenze dell'utenza che incontra: costituisce infatti una aree di intervento cui è determinante l'approccio ragionato sul singolo utente. Il presente articolo si propone riportare gli esiti dell'intervento riabilitativo proposto nella Casa famiglia Villa Martelli presso Iolo (Prato), struttura residenziale gestita da personale non sanitario (suore domenicane) opera stretta connessione con educatori e operatori del Servizio...
To provide a prospective 2 year follow-up of previously enrolled adolescent high school sample, regarding body image and eating concerns, patterns sports type physical activity. Sports type, weekly time devoted to it, psychopathological self-reports (Eating Disorders Examination Questionnaire 6.0, Body Uneasiness Test, Muscle Dysmorphia Disorder Inventory) were evaluated longitudinally in general population sample previous study, testing variations an observational setting. At follow-up,...
Abstract Aim The study aimed to determine trends in the prevalence of underweight, overweight, obesity and their putative risk factors different cohorts from a representative population adolescents Central Italy. Subject methods After random sampling, five attending public high schools – aged 14 18 years were evaluated 2005 2018 (n: 25,174). Collected information included self-reported body mass index (BMI), descriptors family environment, eating behaviour, physical activity, screen use,...
Aberrant salience (AS) is an anomalous world experience which plays a major role in psychotic proneness. In the general population, deployment of this construct - encompassing personality traits, psychotic-like symptoms, and cannabis use could prove useful to outline relative importance these factors. For purpose, 106 postgraduate university students filled AS Inventory (ASI), Community Assessment Psychic Experiences (CAPE), Temperament Character (TCI), Symptom Checklist 90-Revised...
Abstract Funding Acknowledgements Type of funding sources: None. Background Anorexia Nervosa (AN) is a psychiatric disorder that can lead to cardiac complications, especially in severely malnourished patients. Cardiovascular involvement includes autonomic dysfunction (increased vagal tone, bradycardia, orthostatic hypotension, syncope), arrhythmias, pericardial effusion, heart failure and sudden death. A few studies have examined the echocardiographic abnormalities secondary AN, reporting...
In urban contexts, Mental Health Services are increasingly involved in the assessment of users with a heterogeneous ethnic and cultural background. These characteristics migrants can exert an influence on access to healthcare, diagnostic evaluation, use therapeutic resources. The present work aimed compare these differences among individuals who received their first clinical evaluation at Outpatient Service Prato 2019-2021, exploring variations across time, entire non-native population,...
Introduction Clinical relapses in schizophrenia remain a frequent event. Long-acting injectable (LAI) antipsychotics enhance adherence, but low blood levels can sometimes be observed despite an adequate posology. Nonetheless, the evaluation of this parameter is uncommon clinical practice. Objectives To explore potential advantages therapeutic drug monitoring (TDM) LAIs as predictor relapse clinically stable outpatients with schizophrenia. Methods 44 individuals who had reached...
Abstract Background Aberrant salience is the incorrect assignment of salience, significance, or value to different innocuous stimuli that might precede onset psychotic symptoms. The present study aimed perform a preliminary evaluation potentially correlations between Salience Inventory (ASI) score and dimensional categorical diagnostic approaches. Methods 168 adult outpatients with current psychiatric diagnosis were consecutively enrolled. Patients evaluated using psychometric scales. ASI...
Introduction Sexual dysfunction is common in eating disorders (EDs), but its relevance often overlooked. Objectives To describe different ED clinical subgroups terms of psychopathology, putative biological correlates, and consequences dysregulated sexuality, focusing on the role childhood trauma. Methods Healthy controls (n=60), binge-purging (n=38), restricting patients (n=24) were compared (age- BMI-adjusted ANOVA; Bonferroni post-hoc tests), using total scores Eating Disorder Examination...