Root canal treatment addresses infectious processes that require control. Occasionally, the radicular pulp is vital and inflamed, presenting a superficial infection. To preserve pulpal remnants, conservative procedures have gained favor, employing anti-inflammatory medications. This study investigated effects of propolis (PRO), copaiba oil-resin (COR) associated with hydrocortisone (H) compared their impact to Otosporin® concerning cytotoxic genotoxic activity, cytokine detection, toxicity...

O Brasil, com sua rica biodiversidade, abriga a Amazônia, maior floresta tropical do mundo. A Quassia amara, encontrada na América Central e Sul, é uma planta perene de valor medicinal. fenologia, que estuda os ciclos das plantas, essencial para otimizar o uso recursos naturais prever impactos mudanças climáticas, ajudando conservação no manejo sustentável da biodiversidade. estudo teve como objetivo avaliar frequência dos eventos floração frutificação Q. correlacionando esses as condições...

There have been ethnoveterinary reports from around the world investigating plant usage in therapeutic protocols; however, there is no information regarding practices Brazilian Amazonia. The objective of this work was to register and document knowledge inhabitants Island Marajó, eastern Amazonia, Brazil. In study, interviews were conducted with 50 individuals, application semi-structured questionnaires that quantitatively analyzed using descriptive statistic methods frequency distribution....

The oil-resin of Copaifera reticulata Ducke is used in the Brazilian folk medicine as an anti-inflammatory and healing agent. However, there are no investigations on possible neuroprotective roles copaiba (COR) after neural disorders. We have investigated effects COR following acute damage to motor cortex adult rats. Animals were injected with neurotoxin N-Methyl-D-Aspartate (NMDA) (n = 10) treated a single dose (400 mg/kg, i.p.) soon surgery (Group 1) or two daily doses (200 during 3 days...

The present study investigated the action of copaiba oil (Copaifera reticulata) on systemic inflammation, oxidative status, and liver cell metabolism rats with adjuvant-induced arthritis. later is an experimental autoimmune pathology that shares many features human rheumatoid Holtzman were distributed into following groups: control (healthy) rats; treated at doses 0.58 1.15 g · kg-1 , arthritic rats, (0.58 ). was administrated orally once a day during 18 days after arthritis induction. Both...

http://dx.doi.org/10.5902/1980509819618O trabalho teve o objetivo de avaliar comportamento da espécie Schizolobum parahyba var. amazonicum (Huber ex Ducke) Barneby (paricá) diferentes idades e sistemas cultivo no município Aurora do Pará (PA - Brasil). O experimento foi conduzido campo experimental Tramontina Belém S.A (2°10’00”S; 47°32’00”W), seguindo delineamento estatístico inteiramente ao acaso com parcelas subdivididas. Foram selecionadas seis plantações florestais paricá: 1 Sistema...

The regeneration of integrity and tissue homeostasis after injury is a fundamental property involves complex biological processes fully dynamic interconnected. Although there are medications prescribed to accelerate the process wound healing by reducing exaggerated inflammatory response, comes need search for different compounds Amazonian biodiversity that can contribute acceleration process. Among these products, copaiba oil-resin one most prominent feature in this scenario, as they have...

The phenolic content of the medicinal species Connarus perrottetti var. angustifolius Radlk., Connaraceae, Cecropia obtuse Trécul, palmata Willd., Urticaceae; and Mansoa alliacea (Lam.) A.H.Gentry, Bignoniaceae, collected in three different years was evaluated. Plant infusions hydroalcoholic, butanol ethyl acetate extracts were analyzed by high-performance liquid chromatography with diode array detection. In order to endorse these results, analysis electrospray mass spectrometry also...

The effects of topical copaiba oil extract and corticosteroid were assessed on oral wound healing in an vivo model using 96 male Wistar rats. Traumatic ulcers caused the dorsum tongue a 3-mm punch tool. animals divided into: Control; Corticosteroid; Placebo Copaiba Group. received two daily applications products. control group only handling. Six rats each euthanized at days 3, 5, 10 14. monitored to determine status. weigh was day 0 euthanasia day. percentage repair calculated,...

An analytical method using liquid chromatography-atmospheric pressure photoionization tandem mass spectrometry with toluene as a dopant was developed for the determination of triterpenes in medicinal plant extracts. The 12 compounds determined have been shown to exhibit biological activity, such gastroprotective, hepatoprotective, anti-inflammatory, antiviral and anti-tumor effects. parameters atmospheric interface were optimized obtain highest possible sensitivity all compounds. limits...

O óleo-resina de copaíba obtido do gênero Copaifera L., Fabaceae, é largamente utilizado na medicina popular como antiinflamatório, antimicrobiano e antitumoral. Porém, informações sobre seu potencial tóxico são escassos literatura. objetivo deste estudo foi estabelecer a toxicidade oral aguda os possíveis efeitos neurotóxicos relacionados à ingestão reticulata Ducke, em ratas Wistar. conduzido com quinze nulíparas distribuídas nos grupos doses 300 2000 mg/kg pc administrado por gavagem. Os...

In traditional communities of the Brazilian Amazon, copaiba oleoresin (C. reticulata Ducke) is widely known for its therapeutic activity, especially wound healing and anti-inflammatory actions. Our study aimed to evaluate these effects in oral lesions safety dosage proposed. A punch biopsy was induced on ventral surface tongue forty-five male Wistar rats under anesthesia. Animals were randomly allocated one three groups based treatment: control, corticoid copaiba. daily dose each treatment...

Abstract The oleoresins of three trees Copaifera duckei Dwyer were harvested from September 2003 at one-month intervals up to 2004, and the volatiles examined by GC-FID GC/MS. highest oleoresin Sample A occurred October May 2004 (in later dry season early rainy season); B season), C in June season). percentage major Samples (Sample A: β-caryophyllene, trans-α-bergamotene, β-selinene β-bisabolene; C: β-caryophyllene β-bisabolene) changes a minor extent during seasons. However, appreciable...

O objetivo do presente trabalho foi investigar o potencial antimicrobiano oleorresina de Copaifera reticulata Ducke em isolados Staphylococcus coagulase positiva (SCP) provenientes casos otite externa cães. método microdiluição caldo utilizado para determinação da concentração inibitória mínima (CIM) e bactericida (CBM) copaíba. Em adição, determinado perfil suscetibilidade aos antimicrobianos dos SCP pelo difusão ágar. Oito classes foram usadas cálculo multirresistência antimicrobiana. A...

RESUMO O estudo fenológico tem como finalidade determinar o ritmo sazonal dos eventos do ciclo de vida da planta, floração e frutificação. Estes são determinados por uma série fatores, como: alternância períodos chuvosos ou não chuvosos, intensidade radiação solar, entre outros. A fitoquímica objetivos conhecer os constituintes químicos espécies vegetais avaliar sua presença. presente trabalho teve objetivo realizar a caracterização fenológica prospecção folhas jaborandi. área para avaliação...

Através da micropropagação na área agrícola as plantas medicinais têm sido bastante difundidas com perspectiva para obtenção de novas espécies que servirão como fonte compostos biologicamente ativos e aprimoramento produção fitofármacos. A luz é um dos requisitos mais importantes o desenvolvimento plântulas cultivadas in vitro, pois pode influenciar nos aspectos morfológicos, anatômicos fisiológicos através irradiância ou fótons incidem numa superfície a das folhas isso fenômenos biológicos...

The aim of this work was to study the morphogenetic responses zygotic embryos açai palm (Euterpe oleracea Mart.) submitted several conditions in vitro culture. Several research experiments were conducted, laboratory, using vegetable material collected from plants at Embrapa Amazon Oriental, Belém-PA, Brazil. It possible verify expression a direct, repetitive and no-synchronized model somatic embryogenesis mature cultivated primary MS medium supplemented with 2,4-D (339.36 muM) transferred...

A method for the separation, identification and quantification of 24 phenolic compounds using ultra-high performance liquid chromatography coupled to tandem mass spectrometry (UHPLC-MS/MS) was developed validated.

The aim of this paper is to provide an overview on the chemical composition triterpenes in widespread used folk medicine species, through development and validation eleven compounds using HPLC-UV detection. were separated isocratic elution, a reverse phase column (Kinetex C18, 250 mm × 4.6 mm, 5 μm) with mobile consisted acetonitrile:tetrahydrofuran (90:10, v/v), flow-rate 0.5 ml/min detection 210 nm. Diverse parameters successfully evaluated. samples Bauhinia variegata L., B. var. candida...

Plant roots, leaves, barks, seeds berries, or flowers can be used to promote health and treat diseases also have compounds that provide information about the best quality of raw materials. A medicinal plant native Amazonia region (Brazil) was investigated in this work. For purpose, a new analytical approach developed by capillary zone electrophoresis (CZE) with UV detection for separation 14 phenolic extracted from extracts. The method enabled simultaneous determination 3-acetylcoumarin,...

This work describes the chemical characterization of extracts Jatropha gossypiifolia (from Amazonia region) concerning presence phenolic and triterpenic compounds using Ultra High Perfomance Liquid chromatography coupled to Mass Spectrometry in Tandem (UHPLC-MS/MS) methods. The studied belong most frequently found classes medicinal plants (triterpenes, flavonoids, flavones, hydroxycinnamic acids, coumarins, catechins stilbenes), which have been analyzed as bioactive markers hydroethanolic...