A5047114970- Salivary Gland Tumors Diagnosis and Treatment
- Oral and Maxillofacial Pathology
- Head and Neck Cancer Studies
- Ear and Head Tumors
- Laser Applications in Dentistry and Medicine
- Oral health in cancer treatment
- Oral Health Pathology and Treatment
- Nonmelanoma Skin Cancer Studies
- Bone Tumor Diagnosis and Treatments
- Reconstructive Facial Surgery Techniques
- Neuroblastoma Research and Treatments
- Tumors and Oncological Cases
- Histone Deacetylase Inhibitors Research
- Cancer Diagnosis and Treatment
- Head and Neck Surgical Oncology
- Dental Research and COVID-19
- Dermatologic Treatments and Research
- Photodynamic Therapy Research Studies
- Oral and gingival health research
- Cancer Cells and Metastasis
- Cancer Genomics and Diagnostics
- Facial Rejuvenation and Surgery Techniques
- Epigenetics and DNA Methylation
- Soft tissue tumor case studies
- RNA modifications and cancer
Universidade de São Paulo
2023-2025
University of Sheffield
2020-2024
Johannes Gutenberg University Mainz
2024
Universidade Estadual de Campinas (UNICAMP)
2018-2024
Universidade Federal do Rio Grande do Sul
2014-2023
University of Michigan
2016-2020
Hospital de Clínicas da Unicamp
2019
Hospital de Clínicas de Porto Alegre
2016-2017
University of Rio Grande and Rio Grande Community College
2017
Aurora Periodontics and Implant Dentistry
2017
Epigenetics refers to changes in cell characteristics that occur independently of modifications the DNA sequence. Oral carcinogenesis is influenced by epigenetic mechanisms, including histones, which are proteins support chromatin remodelling for dynamic regulation gene expression and silencing. The dysregulation histone acetylation can lead uncontrolled activity different genes, thereby triggering events associated with malignant transformation. aim this study was analyse acetyl-histone H3...
The aim of the present prospective study was to evaluate impact laser phototherapy (LPT) on healing oral ulcers. Different power densities were used wounds in Wistar rats (n=72) randomly divided into three groups: control (0 J/cm2), 4 J/cm2 laser, and 20 laser. Ulcers (3 mm diameter) made dorsum tongue with a punch. Irradiation an indium-gallium-aluminum-phosphide (660 nm; output power: 40 mW; spot size: 0.04 cm2) performed once day close contact ulcer for 14 consecutive days. A...
To evaluate the effect of titanium (Ti) particles on oral epithelial cell homeostasis and potential dental implants to release Ti debris upon insertion.Dental with varying surface treatments were employed determine feasibility particle during implant placement as well impact free cells. derived from surfaces isolated cultured in direct contact normal cells for 48 hours. Further, fixed processed immunofluorescence assay detect activation DNA damage response (DDR) using CHK2 BRCA1 molecular...
Purpose: Locoregional recurrence is a frequent treatment outcome for patients with advanced head and neck squamous cell carcinoma (HNSCC). Emerging evidence suggests that tumor mediated by small subpopulation of uniquely tumorigenic cells, is, cancer stem cells (CSC), are resistant to conventional chemotherapy, endowed self-renewal multipotency.Experimental Design: Here, we evaluated the efficacy MEDI0641, novel antibody-drug conjugate targeted 5T4 carrying DNA-damaging "payload"...
The aim of this study was to evaluate the demographic, clinical, and therapeutic characteristics predictive factors poor prognosis in patients with primary oral squamous cell carcinoma (OSCC) Uruguay. Medical records diagnosis OSCC treated between 2000 2010 Uruguayan public hospitals were selected. Data on demographic characteristics, risk factors, clinical features, treatment, outcome collected. Associations independent variables outcomes assessed using Pearson chi-squared Fisher's tests....
Abstract The aim of this study was to evaluate the main oral adverse effects and their relationship with dental care before radiotherapy (RT) combined RT chemotherapy (RT+CT). Additionally, we assessed association other risk factors development these effects. This paper is a retrospective cross-sectional analytical data from medical records patients head neck cancer (HNC) who underwent or RT+CT attended at stomatology unit in southern Brazil hospital. 78 HNC were accessed. Demographic data,...