- Laser Applications in Dentistry and Medicine
- Oral Health Pathology and Treatment
- Oral health in cancer treatment
- Photodynamic Therapy Research Studies
- Medical and Biological Ozone Research
- Dermatologic Treatments and Research
- Curcumin's Biomedical Applications
- Head and Neck Cancer Studies
- Wound Healing and Treatments
- Health and Medical Studies
- Medical and Health Sciences Research
- Skin Protection and Aging
- Salivary Gland Tumors Diagnosis and Treatment
- Synthesis of Organic Compounds
- Neuroblastoma Research and Treatments
- Fungal Infections and Studies
- Pineapple and bromelain studies
- Patient-Provider Communication in Healthcare
- Bee Products Chemical Analysis
- Biochemical Analysis and Sensing Techniques
- Dental Erosion and Treatment
- HIV/AIDS oral health manifestations
- Neuroendocrine Tumor Research Advances
- PI3K/AKT/mTOR signaling in cancer
- IgG4-Related and Inflammatory Diseases
Universidade Federal do Rio Grande do Sul
2019-2025
Universidade Federal do Rio Grande
2023
University of Cologne
2006
München Klinik Bogenhausen
2005
University of Münster
1998
München Klinik Harlaching
1997
Ethanol is one of the psychoactive substances most used by young individuals, usually in an intermittent and episodic manner, also called binge drinking. In adolescent period, brain structures undergo neuromaturation, which increases vulnerability to psychotropic substances. Our previous studies have revealed that ethanol drinking during adolescence elicits neurobehavioral alterations associated with damage. Thus, we explored persistence motor function impairment cerebellum damage context...
Osteoporosis is a disease that related to higher prevalence and greater volumes of apical periodontitis. The purpose this study was evaluate the effect ovariectomy-induced osteoporosis high- or low-level laser photobiomodulation (PBM) on repair periodontitis (AP) in adult female Wistar rats. Sixty rats (n = 120) were randomly allocated into four control 6 teeth) 8 experimental 12 groups, according procedure time evaluation: healthy (GCS14/GCS28), osteoporotic (GCO14/GCO28), sham...
Abstract Background Oral mucositis (OM) is one of the main adverse effects chemotherapeutic agent methotrexate (MTX). Aim To evaluate relationship OM with MTX metabolism time and other toxicities in childhood, cancer patients receiving high‐dose (HD‐MTX). Design Seventy‐seven childhood HD‐MTX for treatment leukaemia, osteosarcoma or lymphoma were evaluated. serum level, hepatic renal function parameters, presence intensity analysed. Results The submitted to 255 cycles chemotherapy. was...
We explored the effects of a mucoadhesive formulation containing curcuminoid (MFC) from Curcuma longa L. extract on oral mucositis (OM) induced by 5‐fluorouracil (5‐FU) in hamsters. Seventy‐two golden Syrian hamsters were randomly allocated into four groups: control, placebo, chamomilla, and MFC. Animals received an intraperitoneal injection 5‐FU at Days 0 2. On 3 4, buccal mucosa was scratched. Therapy initiated Day 5. two applications substances per day according to experimental group. Six...
Photobiomodulation therapy (PBMT) is an effective method for the prevention of oral mucositis. However, effects PBMT on squamous cell carcinoma (OSCC) have not yet been fully elucidated. This study aimed to evaluate impact in OSCC-patient-derived xenograft (OSCC-PDX) model.BALB/c nude mice with OSCC-PDX models were divided into Control, without (n = 8); Immediate irradiation, since one week after tumor implantation 6); and Late tumors reached 200 mm3 6). daily irradiated (660 nm; 100 mW; 6...
Ethanol consumption has been reported to negatively impact on periodontal disease. In particular, oral cavity disorders occur upon ethanol exposure during adolescence, a life period associated with particular patterns of short and intense ('binge-like') that is most deleterious health. The hazardous central effects have linked the overfunction adenosine receptors, which are antagonized by caffeine, bioactive substance present in numerous natural nutrients, can also modify bone metabolism....
Skin ulcers, wounds, or burns represent a burden for health care worldwide. Our aim was to explore the effects of mucoadhesive formulation with Curcuma longa L. extract containing curcumin (MFC) on skin healing in Wistar rats. Fifty-four rats were randomly allocated into 3 groups: control, vehicle, and MFC. A full-thickness circular wound induced back each animal. Two daily applications products performed according experimental group. On days 3, 10, 21, 6 animals group euthanized. Clinical...
This paper intends to describe the demand for referrals stomatology service requested by medical teams inpatients in a reference hospital south of Brazil. research is retrospective cross-sectional descriptive study focusing on data collection and assessment information about unit carried out from January 2008 December 2018. All was obtained management software database, then transferred analyzed individually statistics. A total 4433 cases were referred team, with an average 403 year....
The clinical advantages of light-emitting diode (LED) therapy in skin healing and its underlying mechanism remain subjects ongoing debate.
The present investigation aimed to assess the safety of photobiomodulation (PBM) on oral carcinogenesis process induced by 4NQO, focusing cell proliferation and apoptosis. Sixty-six Wistar rats received systemic 4NQO for 12 (n = 33) 20 weeks 33), divided into Control group, PBM 0.3 J, 1 J. Applications occurred three times a week. At 20, animals were euthanized. immunoreactivity anti-ROS1 anti-p53 antibodies was also assessed. Statistical analysis assessed multiple t-tests, Kruskal-Wallis,...