A5017318928- Crystallization and Solubility Studies
- X-ray Diffraction in Crystallography
- Organoboron and organosilicon chemistry
- Crystallography and molecular interactions
- Chemical Synthesis and Analysis
- Chemical Thermodynamics and Molecular Structure
- Phase Equilibria and Thermodynamics
- Crystal structures of chemical compounds
- Fluorine in Organic Chemistry
- Chemical Synthesis and Reactions
- Synthesis and characterization of novel inorganic/organometallic compounds
- Thermodynamic properties of mixtures
- Molecular Sensors and Ion Detection
- Chemical Synthesis and Characterization
- Analytical Chemistry and Chromatography
- Luminescence and Fluorescent Materials
- Inorganic and Organometallic Chemistry
- Synthesis and Characterization of Heterocyclic Compounds
- Catalytic Cross-Coupling Reactions
- Synthetic Organic Chemistry Methods
- Analytical Chemistry and Sensors
- Nonlinear Optical Materials Research
- Conducting polymers and applications
- Metal-Organic Frameworks: Synthesis and Applications
- Advanced Chemical Sensor Technologies
University of Warmia and Mazury in Olsztyn
2021-2024
Warsaw University of Technology
2013-2023
University of Warsaw
2010-2015
Faculty (United Kingdom)
2015
Wrocław University of Science and Technology
2010
University of Wrocław
2010
University of Twente
2010
Warsaw University of Life Sciences
2007
Universidad de Valladolid
2003
Max-Planck-Institut für Kohlenforschung
1986-1994
Abstract The molecular structure and properties of phenylboronic acid were investigated experimentally using X‐ray structural analysis spectroscopic methods. Infrared (IR) spectroscopy measurements performed to assess the hydrogen bonding strength. experimental part is enhanced by computational results concerning geometrical electronic structure. dimer (basic motif) was on basis density functional theory (DFT) Møller–Plesset second order (MP2) perturbation theory. basis‐set superposition...
A series of substituted phenylboronic acids and benzoxaboroles were evaluated for their antimicrobial activity. Antibacterial antifungal action activity several compounds was tested against Escherichia coli 67, Staphylococcus aureus 209‐p, Mycobacterium luteum VCM B‐868, Aspergillus niger F‐1119 Candida tenuis Y‐70. Substituted have low biological all the investigated species. Benzoxaboroles reveal higher in comparison with corresponding acids. The highest observed small benzoxaborole...
The structures of three ortho-alkoxyphenylboronic acids (2-methoxy-, 2-ethoxy-, 2-isobutoxy-), and diortho-alkoxyphenylboronic (2,6-dimethoxy-, 2,6-diethoxy- 2-isobutoxy-6-methoxy) were determined by single crystal X-ray diffraction. study was undertaken with the intention designing a novel boronic acid having monomeric structure, which to date has been an unavailable building block for engineering. This motif can be enhanced involving two hydroxyl groups at boron atom in intramolecular...
The acidity constants and hydrolytic stability of all isomers fluoro‐substituted phenylboronic acids (F 1 –F 5 ) have been determined by both spectrophotometric potentiometric methods. introduction fluorine into the aromatic ring enhances Lewis boronic acids, depending on position number substituents. Results methods show good agreement in most cases. To explain observed discrepancies for several compounds, studies carried out spectrophotometry. change maximum absorption intensity is...
Benzoxaboroles possessing aryl substituents in the oxaborole ring were synthesized, and their structures determined by single-crystal X-ray diffraction. Structures solid state are centrosymmetric dimers with two intermolecular hydrogen bonds. These compounds investigated using a combination of spectroscopic computational approach, comparing properties unsubstituted compound. Investigated characterized 1H, 13C, 11B NMR spectroscopy solution. Assignment 1H 13C signals was made on basis HSQC...
The analysis of weak interactions in crystals a series fluorosubstituted phenylboronic catechol esters (fphb) supported by Hirshfeld surface is presented. influence the number and positions fluorine atoms on molecular structure discussed compared with results DFT calculations for isolated molecules. symmetry breaking caused intermolecular was detected. substantial differentiation dipole moments generated substitution its consequence packing are analyzed. presence ortho-fluoro substituents...
Coassembly behavior of the double hydrophilic block copolymer poly(4-hydroxystyrene)-block-poly(ethylene oxide) (PHOS-PEO) with three amphiphilic phenylboronic acids (PBA) differing in hydrophobicity, 4-dodecyloxyphenylboronic acid (C12), 4-octyloxyphenylboronic (C8), and 4-isobutoxyphenylboronic (i-Bu) was studied alkaline aqueous solutions mixtures NaOHaq/THF by spin-echo (1)H NMR spectroscopy, dynamic electrophoretic light scattering, SAXS. The study reveals that only coassembly C12...
2-Formylphenylboronic acids display many interesting features, not only from synthetic but also an application as well structural points of view. 5-Trifluoromethyl-2-formyl phenylboronic acid has been synthesized and characterized in terms its structure properties. The presence electron-withdrawing substituent results a considerable rise the acidity comparison with analogues. In some solutions, title compound isomerizes formation corresponding 3hydroxybenzoxaborole. Taking into account...
A series of cyclic esters pentafluorophenylboronic acid have been obtained and their Lewis acidity evaluated experimentally by a modified Gutmann method. The results based on 31P NMR measurements were compared with those determined quantum mechanical calculations at the DFT-VSXC/pcS-2 level theory. differences in are discussed basis electronic geometric parameters. revealed that complexes investigated Et3PO multiple conformers wide range calculated shielding constants. Additionally,...
3‐Piperazine‐bis(benzoxaborole) and its bis(phenylboronic acid) analogue were investigated in terms of their fungicidal activity. The study was carried out against five filamentous fungi: Aspergillus terreus , Fusarium dimerum solani Penicillium ochrochloron niger . revealed higher inhibitory activity towards the examined strains than standard antibiotic (amphotericin B), whereas proved to be inactive. unequivocally showed that presence heterocyclic benzoxaborole system is essential for...
Abstract Review: 151 refs.
Summary Objective The aim of the study was to evaluate antiproliferative potential simple phenylboronic acid and benzoxaborole derivatives as well provide preliminary insight into their mode action in cancer cells vitro. Methods activity assessed five diverse cell lines via SRB method (sulforhodamine B) or MTT (3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide) after 72 h treatment. Further studies mechanism consisted influence compounds on cycle progression apoptosis induction,...
Abstract The thermal decomposition of sodium chloracetate under reduced pressure in the presence copper gave glycollide with a yield exceeding 70%. Other salts chloracetic acid can be used equally good results. Metals other than inferior Glycollide serves as convenient starting material for preparation glycollic and its esters.
4 mol Triorganoboroxin (RBO)3 (1) [R = CH3 (1a), C4H5 (1b), C4H9 (1c), C6H5 (1d)] reagieren mit 6 Aluminiumtrihalogenid AlHal3 (2) [Hal Cl (2a), Br (2b)] unter Abspaltung von Dihalogenorganoboran RBHal2 (3) Cl: 3aa (R CH3), 3ba C2H5), 3ca C4H9), 3da C6H5); Hal Br: 3bb C2H5)] in hohen Ausbeuten zu 2 der neuen Verbindungen Zusammensetzung R4Al3B4Hal5O6 (MS-Analysen) 4aa 4ba 4ca 4da 4bb C2H5)]. Die Struktur 4aa, 4ba, und Lösung ermittelte man Hilfe spektroskopischer Daten (IR; 1H-, 11B-, 17O-...