A5033344367- Crystallization and Solubility Studies
- X-ray Diffraction in Crystallography
- Crystallography and molecular interactions
- Crystal structures of chemical compounds
- Metal complexes synthesis and properties
- Carbohydrate Chemistry and Synthesis
- Vanadium and Halogenation Chemistry
- Cancer therapeutics and mechanisms
- Synthesis and Biological Evaluation
- Synthesis and biological activity
- Phenothiazines and Benzothiazines Synthesis and Activities
- Bioactive Compounds and Antitumor Agents
- Molecular Sensors and Ion Detection
- Organometallic Complex Synthesis and Catalysis
- Fluorine in Organic Chemistry
- Synthesis of Organic Compounds
- Metal-Organic Frameworks: Synthesis and Applications
- Analytical Chemistry and Chromatography
- Chemical Synthesis and Analysis
- Synthesis and Characterization of Heterocyclic Compounds
- Enzyme Structure and Function
- Magnetism in coordination complexes
- Metal-Catalyzed Oxygenation Mechanisms
- Nonlinear Optical Materials Research
- Organic and Molecular Conductors Research
University of Gdańsk
2016-2025
Faculty (United Kingdom)
2016
The University of Sydney
1989-2004
Gdańsk University of Technology
2003
The approaches to design and control intermolecular interactions for a selective enhancement of specific process(es) are high interest in technologies using molecular materials. Here, we describe how π–π stacking enables over the heavy-atom effect spin–orbit coupling (SOC) through dimerization an organic emitter solid media. red thermally activated delayed fluorescence (TADF) Ac-CNBPz afford types dimers. In its brominated derivative Ac-CNBPzBr, vicinity Br atom electronic density dimer...
The crystal structures of three novel oxidovanadium(IV) salts containing the [VO(acac)(oda)]‐ anion (acac = acetylacetonate, oda oxydiacetate) and quinolinium ([QH]+), isoquinolinium ([(isoQ)H+) acridinium ([(acr)H+)] counterions, molecular formulas [QH][VO(acac)(oda)] (1), [(isoQ)H][VO(acac)(oda)](H2O) (2) [(acr)H][VO(acac)(oda)](H2O)2 (3) are reported. Notably, these complexes represent first structurally characterized comprising heteroligand complex anion. A comprehensive physicochemical...
In silico studies indicate that the Schiff base derived from 4-hydroxybenzaldehyde and 4-aminobenzoic acid may be a promising agent capable of crossing blood-brain barrier predict its binding to active sites AChE CA II.
A cocrystal of acridine with 2,4-dihydroxybenzaldehyde (2:1 stoichiometric ratio) was synthesized, spectrally and structurally characterized using TG, DSC, ATR-FTIR Single-Crystal XRD methods Hirshfeld surface analysis, its nonlinear optical properties were investigated by DFT at the B3LYP/6-311++Glevel. The obtained compound crystallizes in noncentrosymmetric P21 monoclinic space group, two molecules one molecule asymmetric unit. strong O(aldehyde)–H⋯N(acridine) weak...
Currently, researchers are actively seeking chemical compounds capable of absorbing CO₂, as it is a major greenhouse gas. Our study focused on structural modifications in the synthesis poly(2-chloro-2-propen-1-ol) to...
The low water solubility of benzodiazepines seriously affects their bioavailability and, in consequence, biological activity. Since co-crystallization has been found to be a promising way modify undesirable properties active pharmaceutical ingredients, the objective this study was prepare co-crystals two benzodiazepines, chlordiazepoxide and lorazepam. Using different procedures, slurry evaporation liquid-assisted grinding, with p-aminobenzoic acid lorazepam nicotinamide were prepared for...
The nature of keV ion damage buildup and amorphization in AlxGa1−xAs at liquid-nitrogen temperature is investigated for various Al compositions using Rutherford backscattering channeling, transmission electron microscopy, situ time-resolved-reflectivity techniques. Two distinct processes are observed depending on content. At low content, the behavior similar to GaAs whereby collisional disorder ‘‘frozen in’’ proceeds with increasing dose via overlap cascades small amorphous zones created by...
Three groups of furanoses with restricted freedom rotation on the C3-C4, C2-C3, and C1-C2 bonds, respectively, are presented. Conformational analysis these is conducted based proton nuclear magnetic resonance (1H NMR) spectroscopy, density functional theory (DFT) calculations, X-ray analysis. It shown that particular group presented locked in specific conformation. These 1T2-like, 0E-like, 3T4-like conformation, respectively. Characteristic 1H NMR spectra three conformations factors...
Salicylic and acetylsalicylic acids ethacridine have complementary bioactive properties. They can be combined to obtain double-drug multicomponent crystals. Their reactivity in different environments was explored the possible compounds, stable at hydration degrees. Solution, liquid-assisted grinding, dry preparation approaches were applied couples of reactants stoichiometric ratios. Four compounds obtained, three out them reproducible enough determine their structures using SCXRD or PXRD...
A series of nine co-crystals formed from acridine and benzoic acids have been synthesized structurally characterized the influence halogen substituent on formation hydrogen bonding in title compounds has investigated.
The new type of catalysts designed for the olefin derivatives polymerization has been synthetized. novel are chromium(III) salt complexes composed both organic cation and anion, i.e. [Cr(dipic)
Crystal structures of eight salts 9-aminoacridine – chloride monohydrate (1), bromide (2), iodide (3), methanolate (4), (5), (6), fluoride dihydrate (7) and (8) have been studied. The ions solvent molecules in the crystal 1–8 interact via N–H⋯X, O–H⋯X C–H⋯X hydrogen bonds (where X = O, F, Cl, Br or I), producing different types supramolecular synthons consisting amine groups 9-aminoacridinium cations, halide anions molecules. hybrid dihalide–dihydrate clusters [X2(H2O)2]2− are observed...
The physicochemical characterizations of<bold>PAOX</bold>were obtained both in solid-state and solution, its two anti-conformers were observed the X-ray. Its antimicrobial properties tested against reference strains of bacteria yeast.
Oxidative stress plays an important role in the pathogenesis of many serious diseases, including cancer, atherosclerosis, coronary artery disease, Parkinson's Alzheimer's stroke and myocardial infarction. In body's natural biochemical processes, harmful free radicals are formed, which can be removed with help appropriate enzymes, a balanced diet or supply synthetic antioxidant substances such as flavonoids, vitamins anthocyanins to body. Due growing demand for substances, new complex...
Efficient radiotherapy requires the concomitant use of ionizing radiation (IR) and a radiosensitizer. In present work uracil-5-yl O-sulfamate (SU) is tested against its radiosensitizing potential. The compound possesses appropriate dissociative electron attachment (DEA) characteristics calculated at M06-2X/6-31++G(d,p) level. Crossed electron–molecular beam experiments in gas phase demonstrate that SU undergoes efficient DEA processes, single C–O or S–O bond dissociations account for...