A5073118490- Pharmacogenetics and Drug Metabolism
- Multiple Myeloma Research and Treatments
- Influenza Virus Research Studies
- Liver Disease Diagnosis and Treatment
- Multilevel Inverters and Converters
- Magnetic Properties and Applications
- Receptor Mechanisms and Signaling
- Synthesis and Biological Evaluation
- Chronic Lymphocytic Leukemia Research
- Electric Motor Design and Analysis
- Machine Fault Diagnosis Techniques
- Monoclonal and Polyclonal Antibodies Research
- Advanced Sensor and Control Systems
- Reproductive System and Pregnancy
- Cancer, Hypoxia, and Metabolism
- Microgrid Control and Optimization
- Fault Detection and Control Systems
- Drug-Induced Hepatotoxicity and Protection
- TGF-β signaling in diseases
- Biosimilars and Bioanalytical Methods
- Advanced Algorithms and Applications
- Hybrid Renewable Energy Systems
- Diabetes Management and Education
- Induction Heating and Inverter Technology
- Gynecological conditions and treatments
China West Normal University
2025
Janssen (United States)
2016-2024
Huaiyin Institute of Technology
2005-2022
Lanzhou Jiaotong University
2021
Army Medical University
2019-2020
Southwest Hospital
2020
Chongqing Medical University
2019
The Affiliated Yongchuan Hospital of Chongqing Medical University
2019
South China University of Technology
2017
Chinese Academy of Fishery Sciences
2015
Cytokine release syndrome (CRS) was associated with teclistamab treatment in the phase I/II MajesTEC-1 study. Cytokines, especially interleukin (IL)-6, are known suppressors of cytochrome P450 (CYP) enzymes' activity. A physiologically based pharmacokinetic model evaluated impact IL-6 serum levels on exposure substrates various CYP enzymes (1A2, 2C9, 2C19, 3A4, 3A5). Two kinetics profiles were assessed, mean profile a maximum concentration (C
Abstract Background Daratumumab is a human CD38‐directed monoclonal antibody indicated for the treatment of relapsed and refractory multiple myeloma (MM). Methods A multicenter, open‐label protocol provided early access to daratumumab patients who had progressive MM after they received ≥3 prior lines therapy that included proteasome inhibitor an immunomodulatory agent or if were both agent. Patients 16 mg/kg weekly 8 weeks, every other week monthly until developed disease progression,...
To reduce the allocation of energy storage capacity in wind farms and improve economic benefits, this study is focused on virtual synchronous generator (synchronverter) technology. A system accompanied by power, storage, a load presented detail. brief description control strategy given. The based different optimization goals optimal configuration coordinated frequency modulation (FM) strategy. detail dual-loop carried out establishing grid-connected transfer function model synchronverter...
For achieving higher energy transferring efficiency from the resources to load, Combined Cooling, Heating, and Power (CCHP) systems have been widely researched applied as an efficient approach. The key idea of this study is designing a novel structure hybrid CCHP system evaluating its performance. In research, there storage unit enhancing whole system’s operation flexibility while supplying cooling, heating, power. An ORC integrated into which takes responsibility absorbing low-temperature...
When renal epithelial cells are exposed to epidermal growth factor-transforming factor-β1 (EGF-TGF-β1) the typical EGF-mediated hyperplastic response is converted a hypertrophic response. Hypertrophy in this setting involves cell entrance into G 1 , but arrest of cycle progression at /S interface. Late mediated by retaining retinoblastoma protein (pRB) its active, hypophosphorylated state. The present studies examine mechanism which pRB retained active results demonstrate that...
ABSTRACT Twelve volunteers completed a two-sequence, three-way crossover study of single 900-mg aspirin dose and multiple doses 75 mg oseltamivir in the absence presence 900 aspirin. The plasma urine results demonstrated no pharmacokinetic interaction between
The flux-concentrating permanent-magnet (FCPM) machine with two V-shape magnet pieces in one stator pole has attracted considerable attention due to its excellent torque density and permanent (PM) usage efficiency, whereas the ripple of FCPM is usually high. This article aims make a multiobjective optimization design for machine. process divided into three steps different objectives on sets geometric variables at operation conditions. simulated results show that output optimized increased...
The DC bus voltage stability control is one key technology to ensure that Active Power Filter (APF) operates stably. external disturbances such as power grid and load fluctuation the system parameters changing may affect of APF normal operation APF. mathematical model established according balance principle a piecewise reaching law variable structure algorithm proposed solve above problem, design method given. simulation experiment results proved can eliminate chattering problem existing in...
Data remains limited about the optimal nucleos(t)ide analogue therapy for patients infected with hepatitis B virus (HBV) while treated glucocorticoids because of kidney diseases. We aim to evaluate safety and efficacy long-term antiviral telbivudine (LdT) entecavir (ETV) in this specific population. In prospective randomized controlled study, a total 60 both diseases chronic were randomly divided into LdT group ETV group. analyzed changes estimated glomerular filtration rate (eGFR),...