- MicroRNA in disease regulation
- Cancer-related molecular mechanisms research
- Circular RNAs in diseases
- Inflammasome and immune disorders
- Cancer, Lipids, and Metabolism
- Extracellular vesicles in disease
- Pregnancy and preeclampsia studies
- Protease and Inhibitor Mechanisms
- Peptidase Inhibition and Analysis
- Reproductive System and Pregnancy
- Studies on Chitinases and Chitosanases
- Nutrition, Genetics, and Disease
Yangpu Hospital of Tongji University
2016
Gastric cancer (GC) continues to be the most common gastrointestinal malignancy in China, and tumor metastases are a major reason for poor prognosis. Circular RNAs (circRNAs) an intriguing type of noncoding with important regulatory roles. However, roles circRNAs GC metastasis have not been fully elucidated. Here, we reported that circ-transportin 3 (TNPO3) was significantly downregulated 103 pairs tissues compared matched noncancerous tissues. The level circ-TNPO3 expression correlated...
BACKGROUND: Gastric cancer is one of the leading causes death worldwide. MicroRNA-30a (miR-30a) has been demonstrated to be involved in several types development. OBJECTIVE:We aimed identify molecular mechanism miR-30a gastric cancer. METHODS:We investigated expression tissues by qRT-PCR. The role on metastasis and proliferation was evaluated cell migration assay, CCK-8 assay tumor peritoneal dissemination model. target identified. RESULTS:We discovered that significantly downregulated...
Golgi phosphoprotein 3 (GOLPH3) has been demonstrated to promote tumor progression in various gastrointestinal malignancies. However, its effects gallbladder carcinoma (GBC) remain unknown. In the present study, expression levels of GOLPH3 and nucleotide‑binding domain leucine‑rich repeat pyrin containing receptor (NLRP3) human GBC tissues were detected by immunohistochemistry, clinical data survival these patients analyzed. Next, whether could affect proliferation via regulation NLRP3...
Effects of a Protein Optimized Diet Combined with Moderate Resistance Training on the Postoperative Course in Older Patients Hip Fracture