Léo Boussamet

ORCID: 0000-0001-8437-666X
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About
Contact & Profiles
Research Areas
  • Gut microbiota and health
  • Salivary Gland Disorders and Functions
  • Diabetes and associated disorders
  • vaccines and immunoinformatics approaches
  • Transplantation: Methods and Outcomes
  • Clostridium difficile and Clostridium perfringens research
  • Pulmonary Hypertension Research and Treatments
  • Immune Cell Function and Interaction
  • Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
  • Genomics and Rare Diseases
  • Celiac Disease Research and Management
  • Immunodeficiency and Autoimmune Disorders
  • Mycobacterium research and diagnosis
  • Xenotransplantation and immune response

Inserm
2021-2024

Nantes Université
2021-2024

Center for Research in Transplantation and Translational Immunology
2021-2024

Centre Hospitalier Universitaire de Nantes
2021-2024

Institut de Transplantation Urologie en Nephrologie
2021

Abstract In multiple sclerosis (MS), alterations of the gut microbiota lead to inflammation. However, role other microbiomes in body MS has not been fully elucidated. a pilot case-controlled study, we carried out simultaneous characterization faecal and oral conducted an in-depth analysis bacterial associated with MS. Using 16S rRNA sequencing metabolic inference tools, compared oral/faecal metabolism pathways French patients (n = 14) healthy volunteers (HV, n 21). A classification model...

10.1038/s41598-024-57949-4 article EN cc-by Scientific Reports 2024-04-02

The HLA system plays a pivotal role both in transplantation and immunology. While classical genotypes matching is made at the allelic level, recent progresses were developed to explore antibody-antigen recognition by studying epitopes. Donor recipient epitopic level becoming trending topic research field because anti-HLA antibodies are epitope-specific rather than allele-specific. Indeed, different alleles often share common We present HLA-Epi tool (hla.univ-nantes.fr) study an genotype...

10.1111/tan.14505 article EN HLA 2021-12-04
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