- Epilepsy research and treatment
- Spinal Dysraphism and Malformations
- Fetal and Pediatric Neurological Disorders
- Neonatal and fetal brain pathology
- Functional Brain Connectivity Studies
- Cerebrospinal fluid and hydrocephalus
- Traumatic Brain Injury and Neurovascular Disturbances
- EEG and Brain-Computer Interfaces
- Vascular Malformations Diagnosis and Treatment
- Intracranial Aneurysms: Treatment and Complications
- Hemoglobinopathies and Related Disorders
- Head and Neck Surgical Oncology
- Neuroscience and Neural Engineering
- Blood groups and transfusion
- Neural dynamics and brain function
- Glioma Diagnosis and Treatment
- Intracerebral and Subarachnoid Hemorrhage Research
- Radiology practices and education
- Advanced Neuroimaging Techniques and Applications
- Teratomas and Epidermoid Cysts
- Atomic and Subatomic Physics Research
- Neurological disorders and treatments
- Vagus Nerve Stimulation Research
- Acute Ischemic Stroke Management
- Chromatin Remodeling and Cancer
Children's Hospital of Philadelphia
2015-2025
Boston Children's Hospital
2025
Harvard University
2025
University of Pennsylvania
2014-2023
Office of Diversity and Inclusion
2023
Hospital of the University of Pennsylvania
2022
Children's Hospital
2020
University of Kansas Medical Center
2020
Imaging Center
2009-2017
Heliophysics
2011
<h3>ABSTRACT</h3> <h3>BACKGROUND AND PURPOSE:</h3> Frontal paraventricular cystic changes have a varied etiology that includes connatal cysts, subependymal pseudocysts, necrosis, and enlarged perivascular spaces. These may be difficult to distinguish by neuroimaging variety of associated prognoses. We aim refine the definition frontal horn cysts correlate it with adverse clinical conditions. <h3>MATERIALS METHODS:</h3> In this cross-sectional study, pre-and postnatal database at quaternary...
Object Myelomeningocele (MMC) is characterized by a defect in caudal neurulation and appears at birth with constellation of neuroanatomical abnormalities, including Chiari malformation Type II. The authors investigated the effects antenatal versus postnatal repair MMC through quantitative analysis morphometric changes posterior fossa (PF). Methods retrospectively reviewed records 29 patients who underwent utero repair, 24 114 fetal pediatric controls. Tonsillar displacement, cerebellum...
Abstract In this repeated measures case study, we show that sensory deafferentation after limb amputation leads to changes in cortical somatotopic maps which are reversible restoration of input. Using magnetoencephalography ( MEG ), observed a child with bilateral hand transplants large‐scale shifts somatosensory lip representation from anatomic area face region. After recovery tactile sensation the digits, responses finger stimulation were localized orthotopic cortex, but atypical...
Advancements in magnetoencephalography (MEG) present new opportunities for clinical pediatric centers faced with the challenge of offering a sensitive diagnostic evaluation epilepsy infants and young children. A noninvasive brain imaging method, which measures magnetic fields generated by electrical activity human brain, MEG provides significant advantages that make it particularly suitable use. First, patient preparation is quick easy and, unlike functional resonance imaging/magnetic...
Ventricular shunt complications in children can be severe and life-threatening if not identified treated a timely manner. Evaluation for obstruction is without risk, including lifetime cumulative radiation as patients routinely receive computed tomography (CT) scans of the brain series (multiple radiographs skull, neck, chest, abdomen).A multidisciplinary team collaborated to develop clinical pathway with goal standardizing evaluation management suspected complication. The implemented...
The purpose of this study was to compare somatosensory responses from a group children with epilepsy and autism spectrum disorder (ASD), age matched TD controls. We hypothesized that the magnitude tactile "P50m" response would be reduced in both patient groups, possibly due GABAergic signaling as has been implicated variety previous animal models vivo human MRS studies. observed significant (~ 25%) decreases P50m dipole moment values source localized response, for ASD. In addition, latency...
Abstract Purpose There is limited data concerning neuroimaging findings and longitudinal evaluation of familial cerebral cavernous malformations (FCCM) in children. Our aim was to study the natural history pediatric FCCM, with an emphasis on symptomatic hemorrhagic events associated clinical imaging risk factors. Methods We retrospectively reviewed all children diagnosed FCCM four tertiary hospitals between January 2010 March 2022. Subjects first available brain MRI $$\ge$$ <mml:math...