A5090158123- Substance Abuse Treatment and Outcomes
- Global Public Health Policies and Epidemiology
- Liver Disease Diagnosis and Treatment
- Alcohol Consumption and Health Effects
- Birth, Development, and Health
- Genetic Associations and Epidemiology
- Obesity, Physical Activity, Diet
- Folate and B Vitamins Research
- Neonatal Respiratory Health Research
- Pancreatic function and diabetes
- Health disparities and outcomes
- Pediatric health and respiratory diseases
- Child Nutrition and Water Access
- Healthcare Systems and Reforms
- Insect behavior and control techniques
- Child and Adolescent Health
- Congenital Diaphragmatic Hernia Studies
- Breastfeeding Practices and Influences
- Forensic Entomology and Diptera Studies
- Homelessness and Social Issues
- Cardiovascular Health and Risk Factors
- Radiology practices and education
- Endoplasmic Reticulum Stress and Disease
- Pharmacological Effects and Assays
- Antimicrobial Resistance in Staphylococcus
Massey University
2021-2024
Centre College
2023
University of Hong Kong
2015-2021
Hospital Authority
2014
Hong Kong Jockey Club
2008
Chinese University of Hong Kong
2008
Cardiovascular disease (CVD) is a major contributor to the global burden of disease. Berberine, long-standing, widely used, traditional Chinese medicine, thought have beneficial effects on CVD risk factors and in women with polycystic ovary syndrome. The mechanisms effects, specifically men, possibly via testosterone, not been examined previously. To assess effect berberine any potential pathway testosterone we conducted randomized, double-blind, placebo-controlled, parallel trial Hong Kong....
Observationally, delivery by Caesarean section is associated with higher risk of childhood asthma and wheeze in developed Western settings, but associations are less consistent other settings.To examine the association mode hospitalizations for wheezing disorders a non-Western setting high rates section.Using Cox regression, we examined adjusted public hospital admissions asthma, bronchitis, bronchiolitis (International Classification Diseases, Ninth Version Clinical Modification 466, 490...
Abstract Background Preterm birth, early term and low birthweight are associated with childhood wheezing disorders in developed Western settings, but observed associations could be confounded by socio‐economic position. This study aims to clarify such a non‐ W estern setting different confounding structure. Methods Using Cox regression, we examined the adjusted of gestational age for time first public hospital admission asthma, bronchitis, bronchiolitis ( I nternational C lassification D...
This study developed a measurement tool to assess stringency and 'on-the-ground' impact of four key alcohol policy domains create an index suitable for benchmarking assessing change over time in middle- high-income countries. It involved collaboration between researchers 12 diverse countries: New Zealand; Australia; England; Scotland; Netherlands; Vietnam; Thailand; South Africa; Turkey; Chile; Saint Kitts Nevis Mongolia. Data on the most effective (availability, pricing policy, marketing,...
Background The alcohol industry uses many of the tobacco industry’s strategies to influence policy-making, yet unlike Framework Convention on Tobacco Control, there is no intergovernmental guidance protecting policies from influence. Systematic assessment penetration and government safeguards also lacking. Here, we aimed identify nature extent in a cross-section jurisdictions. Using these data, suggested ways protect policy-makers undue Methods As part International Alcohol Control Study,...
As China moves to expand primary healthcare services as part of its efforts achieve universal health coverage, <b>June Leung and colleagues</b> discuss the challenges in recruiting, training, keeping general practitioners
Background: The objectives were to evaluate the effectiveness of an infection control bundle in controlling meticillin resistant Staphylococcus aureus (MRSA) transmission residential care homes for elderly (RCHEs) Hong Kong. Methods: This was a two-arm cluster randomised controlled trial. Infection bundles focused on hand hygiene (HH), environmental hygiene, and modified contact precautions applied intervention arm. Nasal swabs from residents; staff HH compliance effectiveness; assessed by...
Background Preterm birth (PTB), low weight and small-for-gestational age (SGA) are associated with lower socioeconomic position (SEP) in developed Western settings, but it is unclear if such disparities persist to the same extent elsewhere, whether associations differ by measure of SEP used. Here, we assessed association PTB, SGA recently non-Western setting Hong Kong where few women smoke or use alcohol. Methods We used multivariable logistic linear regression assess parental neighbourhood...
Abstract We aimed to determine if prematurity and lower birth weight are associated with poorer lung function in a non-western developed setting less marked confounding by socioeconomic position. Using multivariable linear regression Hong Kong’s “Children of 1997” cohort, adjusted associations forced expiratory volume 1 second (FEV ), vital capacity (FVC), flow at 25–75% the pulmonary (FEF ) ~17.5 years were assessed. Associations for stronger boys FEV (boys: 0.31 L, 95% confidence interval...
Abstract Background Alcohol policies stand out among other noncommunicable disease‐relevant for the lack of uptake. Composite indicators have been developed to measure effects alcohol control policy. We investigated whether drinking patterns demographic groups from general population samples drinkers diverse countries are associated with policy as measured by International Control (IAC) Policy Index. Methods Representative adult 10 (five high‐income and five middle‐income) were surveyed...
Abstract Introduction Alcohol abstinence remains common among adults globally, although low and middle‐income countries are experiencing declines in abstention. The effect of alcohol policies on lifetime is poorly understood. International Control (IAC) policy index was developed to benchmark monitor the uptake effective has shown strong associations with per capita consumption drinking patterns. Uniquely, incorporates both ‘stringency’ ‘impact’, reflecting implementation enforcement, across...
Summary Background In developed Western settings, asthma is more prevalent among second‐generation compared to first‐generation migrants. However, these studies are difficult interpret as they include migrants of various ethnicities and countries origin. Objective We assessed the association parental migrant status with wheezing disorders children born in Hong Kong, a non‐Western setting, where many have parents from mainland China same ethnicity. Methods used Cox regression examine adjusted...
The World Health Organization (WHO) has engaged in consultations with the alcohol industry global policy development, including currently a draft action plan to strengthen implementation of Global strategy reduce harmful use alcohol. WHO's Framework for Engagement Non-State Actors (FENSA) is an organization-wide that aims manage potential conflicts interest interactions private sector entities, non-governmental institutions, philanthropic foundations and academic institutions.We analysed...
Abstract Poorer liver function is positively associated with diabetes in Mendelian randomization (MR) studies. Observationally, adiposity poorer function. To clarify the etiology, we assessed association of enzymes observationally and using two-sample MR for validation. In “Children 1997” birth cohort, used multivariable linear regression to assess associations alanine transaminase (ALT) alkaline phosphatase (ALP) at ~17.5 years body mass index (BMI) (n = 3,458). Using MR, genetic predictors...
Background Higher alanine transaminase (ALT), indicating poor liver function, is positively associated with diabetes but inversely body mass index (BMI) in Mendelian randomization (MR) studies, suggesting function affects muscle mass. To clarify, we assessed the associations of enzymes and fat observationally two-sample MR as a validation. Methods In population-representative “Children 1997” birth cohort (n = 3,455), used multivariable linear regression to assess adjusted ALT alkaline...